Search results for "FARM"
showing 10 items of 3554 documents
Implicación del sistema serotoninérgico y dopaminérgico en los efectos reforzantes de la MDMA
2012
La adolescencia constituye un periodo de especial vulnerabilidad al consumo de drogas, siendo los adolescentes los principales consumidores de 3,4- metilendioximetanfetamina (MDMA), un derivado anfetamínico con potencial adictivo. El objetivo del presente trabajo es evaluar el papel de los sistemas dopaminérgico y serotoninérgico en las propiedades reforzantes de la MDMA y en la vulnerabilidad a la recaída en su consumo. En concreto, hemos estudiado la implicación de estos sistemas de neurotransmisión en la adquisición, expresión y reinstauración del condicionamiento de preferencia de lugar (CPL) inducido por MDMA en ratones adolescentes. Para ello utilizamos diferentes agonistas y antagoni…
THE KEY ROLE OF THE CLINICAL PHARMACIST IN THE MANAGEMENT OF ANTICANCER THERAPIES: A PILOT STUDY IN THE TREATMENT OF PATIENTS WITH NON-SMALL CELL LUN…
2021
Lung cancer accounts for a quarter of all mortality cases worldwide. To date, numerous efforts have been done to identify the best therapeutic approach, especially in the advanced stage of the disease, and to extend the overall survival of patients. Careful surveillance of patients during therapy is essential in order to identify undesirable effects and to evaluate possible adverse reactions in case of coadministration. This study aims to compare two types of anticancer therapy, immunotherapy and chemotherapy, administered to NSCLC patients in the Medical Oncology Unit of the ARNAS “Di Cristina Benfratelli” Civic Hospital in Palermo (Italy), and to highlight the key role of clinical pharmac…
Garastāvokļa (afektīvu) traucējumu pacientu līdzestība Latvijā
2020
Afektīvi traucējumi ir plaši izplatīta garīgu saslimšanu grupa, kas raksturojas ar patoloģiskām izmaiņām cilvēka garastāvoklī un ietver depresijas epizodes, rekurentus depresīvus traucējumus un bipolāri afektīvus traucējumus. Zāļu līdzestība jeb veselības aprūpes speciālistu norādījumu ievērošana terapijas laikā šajā pacientu grupā ir nozīmīga, lai sasniegtu vēlamos ārstēšanas rezultātus. Bakalaura darba mērķis ir apkopot datus par afektīvu traucējumu pacientu lietotajām zālēm un līdzestību Latvijā. Pētījuma rezultāti liecina, ka lielākajai daļai afektīvu traucējumu pacientu nozīmētā terapija atbilst Latvijā izmantotajām vadlīnijām. Tā kā liela daļa afektīvu traucējumu pacientu ir nelīdzest…
Parte III. Cap. IX. I Fattori della produzione agricola.
2021
The process of modernization and innovation in the agricultural sector requires careful analysis regarding financial resources and the need to strengthen economic structures within it. The specific discipline of agricultural credit is different from that provided for other productive activities. The "naturalness" of the agricultural product is reflected in the incidence of credit risk. These economic evaluations, which are at the basis of what is known as agricultural exceptionalism, have repercussions on the legal system of access to credit, requiring, for example, a differentiated system of evaluation of creditworthiness.
Cooperation in Managing the Environmental Function in Agriculture as a Condition for Integration of the Borderland Areas of the Czech Republic and Po…
2018
The aim of the study is to justify the need for cooperation in the sphere of managing the environmental function in the agriculture of the borderland areas of Poland and the Czech Republic. Until now, thanks to the so-called “green structure of the Common Agricultural Policy” the environment-related requirements in agriculture have come from the top and have been of the universal character. In the agricultural policy following 2020, it is state governments and multilevel management structures which will have been responsible for programming and implementing environmental and climatic strategies in this sector. In borderland areas, solutions that will be accepted may become a source of confl…
Progress towards sustainable agriculture – Drivers of change
2021
Sustainable Development Goal (SDG) 2 calls for global action to “end hunger, achieve food security and improved nutrition, and promote sustainable agriculture”. Meeting this challenge requires global partnerships to support more productive, nutritious and equitable food systems, while helping to conserve environmental resources and reduce the greenhouse gas (GHG) emissions responsible for global climate change. The Food and Agriculture Organization of the United Nations (FAO) offers a global vision for a more sustainable agriculture that encompasses economic, social and environmental dimensions of food and agriculture systems. This technical study examines the key factors driving changes in…
Dabas vielu lipīdu uzkrāšanās un acetilholīnesterāzes inhibīcija cilvēku aknu šūnu līnijā HepG2 in vitro
2022
Taukaino aknu slimība ir viena no izplatītākajām aknu slimībām attīstītajās valstīs, un tiek iedalīta alkohola un ne-alkohola taukaino aknu slimībā. Taukaino aknu slimībai ir potenciāls progresēt līdz steatohepatītam un cirozei, bet joprojām nav atrastas mērķētas terapijas slimības progresijas palēnināšanai. Maģistra darba mērķis ir pētīt Vaccinium ģints ogu izspaidu ekstraktu iedarbību uz acetilholīna koncentrāciju, acetiholīnesterāzes aktivitāti un lipīdu akumulāciju HepG2 šūnu modelī. Pētījuma rezultāti liecina, ka ogu izspiedu ekstrakti samazina lipīdu akumulāciju šūnās un gan ekstrakti, gan zināmais aknu šūnu funkciju uzlabotājs silimarīns inhibē acetilholīnesterāzes (AChE) aktivitāti.…
Farmaci antimicrotubulari
2020
Farmaci antimicrotubulari
Alcohol and Nicotine Use among Adolescents: An Observational Study in a Sicilian Cohort of High School Students
2022
In recent years, the mode of alcoholic intake known as binge drinking (BD) has become a common practice, especially among adolescents who, due to socio-environmental motives, tend to reach a rapid state of drunkenness. This drunkeness leads to alterations in brain areas responsible for executive functions and cognitive processes, as well as to the genesis of factors that predispose to lasting addiction. Likewise, nicotine leads to a comparable degree of addiction. On this basis, the aim of this research was to evaluate, on a cohort of 349 high school students (15–17 years old) in the province of Palermo, the following: (I) the drinking model of alcoholic beverages; (II) the use of nic…
EL alcoholismo en las últimas clasificaciones : clasificación Internacional CIE 10
2000
A punto de partir de una percepción sistémica de las drogodependencias, el autor hace una valoración clínico epidemiológica de la significación social de la más relevante de las drogadicciones y enfatiza el alcoholismo, que valora como la más trascendente adicción de la actualidad y como uno de los mayores problemas de salud en muchos países, desarrollados o no.Comenta algunos criterios operativos para identificar los distintos comportamientos posibles ante el alcohol y posteriormente destacar el significado del alcohol como "droga portera", y hace un intento por transcribir las diferentes categorías diagnósticas del CIE 10 fundamentalmente.Destaca finalmente la categoría "consumo de riesgo…