Search results for "FGF-1"

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Acute intermittent nicotine treatment produces a reduction in the total number of FGF-2 immunoreactive astroglial cells in the substantia nigra of th…

2004

To understand the morphological substrate of the nicotine effect on nigral FGF-2 expression, a stereological analysis of FGF-2 immunoreactive neuronal and glial profiles has been performed in the substantia nigra of the rat after acute intermittent nicotine treatment. The major finding of this paper is the demonstration that this type of nicotine treatment produces a significant reduction in the total number of nuclear FGF-2 immunoreactive astroglial profiles in the substantia nigra. A parallel analysis of nigral FGF-1 and FGF-5 immunoreactivities showed no effect of this type of nicotine treatment. The results may be explained by an inhibition of FGF-2 synthesis in a subpopulation of nigra…

Malemedicine.medical_specialtyNicotineCentral nervous systemFGF-2Substantia nigraStereologyFGF-1Cell CountBiologyFibroblast growth factornicotine; FGF-2; stereology; immunoreactivity; substantia nigra; FGF-1; FGF-5FGF-5NicotineRats Sprague-DawleyStereotaxic TechniquesInternal medicinemedicineAnimalsGeneral NeuroscienceAlkaloidImmunohistochemistryRatsSubstantia Nigramedicine.anatomical_structureEndocrinologyNicotinic agonistnervous systemsubstantia nigraAstrocytesStereotaxic techniquestereologyFibroblast Growth Factor 2immunoreactivitymedicine.drugnicotineNeuroscience letters

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