Search results for "FLE"

Pourquoi la génétique humaine a-t-elle besoin des sciences humaines et sociales ?

2019

L’introduction récente du séquençage haut débit du génome détermine une situation complexe marquée du sceau de l’accélération ; elle pose des problèmes éprouvés par les patients, les médecins ou les chercheurs à partir d’expériences de pratique clinique ou de recherche. Ces pratiques situées suscitent un besoin de réflexivité souvent difficile à assumer dans l’urgence de l’action et la segmentation encore forte des métiers. La Fédération Hospitalo-Universitaire (FHU) TRANSLAD Bourgogne Franche Comté constitue une structure pluridisciplinaire et plurielle pour encadrer l’arrivée du séquençage haut débit dans le soin. Ne préjugeant pas de ses objets, fonctions ou champs, elle se situe d’abord…

Bivariate nonlinear prediction to quantify the strength of complex dynamical interactions in short-term cardiovascular variability.

2005

A nonlinear prediction method for investigating the dynamic interdependence between short length time series is presented. The method is a generalization to bivariate prediction of the univariate approach based on nearest neighbor local linear approximation. Given the input and output series x and y, the relationship between a pattern of samples of x and a synchronous sample of y was approximated with a linear polynomial whose coefficients were estimated from an equation system including the nearest neighbor patterns in x and the corresponding samples in y. To avoid overfitting and waste of data, the training and testing stages of the prediction were designed through a specific out-of-sampl…

INTEGRAL/RXTE Observations of Cygnus X-1

2003

We present first results from contemporaneous observations of Cygnus X-1 with INTEGRAL and RXTE, made during INTEGRAL's performance verification phase in 2002 November and December. Consistent with earlier results, the 3-250 keV data are well described by Comptonization spectra from a Compton corona with a temperature of kT~50-90 keV and an optical depth of tau~1.0-1.3 plus reflection from a cold or mildly ionized slab with a covering factor of Omega/2pi~0.2-0.3. A soft excess below 10 keV, interpreted as emission from the accretion disk, is seen to decrease during the 1.5 months spanned by our observations. Our results indicate a remarkable consistency among the independently calibrated de…

Obesity interferes with the orosensory detection of long-chain fatty acids in humans

2014

Background: The association between the orosensory detection of lipids, preference for fatty foods, and body mass index (BMI; in kg/m 2 ) is controversial in humans. Objective: We explored the oral lipid-sensing system and the orosensory-induced autonomic reflex system in lean and obese subjects. Design: Lean (BMI: 19 to ,25; n = 30) and obese (BMI .30; n = 29) age-matched men were enrolled. Their oral threshold sensitivity to linoleic acid (LA) was determined by using a 3-alternative forced-choice ascending procedure, and their eating habits were established by the analysis of 4 consecutive 24-h food-consumption diaries. The effect of brief oral lipid stimulations on plasma triglyceride [(…

Towards understanding the complexity of cardiovascular oscillations: Insights from information theory.

2018

Abstract Cardiovascular complexity is a feature of healthy physiological regulation, which stems from the simultaneous activity of several cardiovascular reflexes and other non-reflex physiological mechanisms. It is manifested in the rich dynamics characterizing the spontaneous heart rate and blood pressure variability (HRV and BPV). The present study faces the challenge of disclosing the origin of short-term HRV and BPV from the statistical perspective offered by information theory. To dissect the physiological mechanisms giving rise to cardiovascular complexity in different conditions, measures of predictive information, information storage, information transfer and information modificati…

Multilayered cultural identity and the perception of the self

2012

This qualitative study examines the reciprocal relationship between a person’s multilayered cultural identity (MCI) and the concept of self (CoS), that is presented purely on a theoretical level and encompasses various theories. Nowadays, in an increasingly globalising world, it is not enough to merely look at a national, ethnic or other type of identity. It is important to realise that there are different layers in an identity that one can view themselves through. The ways an individual perceives themselves through their multicultural background can also be different. This thesis helps identify the ways a person can see themselves. The thesis also attempts to explain the varied nature of o…

El capitalismo, contra el planeta / 5

2007

Determination of Brain Death/Death by Neurologic Criteria

2020

Importance: There are inconsistencies in concept, criteria, practice, and documentation of brain death/death by neurologic criteria (BD/DNC) both internationally and within countries. Objective: To formulate a consensus statement of recommendations on determination of BD/DNC based on review of the literature and expert opinion of a large multidisciplinary, international panel. Process: Relevant international professional societies were recruited to develop recommendations regarding determination of BD/DNC. Literature searches of the Cochrane, Embase, and MEDLINE databases included January 1, 1992, through April 2020 identified pertinent articles for review. Because of the lack of high-quali…

A Simple Apparatus for the Determination of the Optical Constants and the Thickness of Absorbing Thin Films

2001

We report on a simple and inexpensive apparatus useful for measuring the optical constants n, k and the thickness of weakly absorbing thin films. The measurement is based on an accurate determination of the reflectance and transmittance of a specimen illuminated by a laser beam. The laser beam is incident on a transparent substrate coated with the film to be evaluated, with an angle of incidence equal to the Brewster angle for the substrate, and its polarization can be switched between the p and s states. If the thickness is known to be within a presumptive range, measurements of the p and s reflectance and transmittance allow a calculation of the optical constants n, k and the thickness of…

Use of fiber-section beam elements for modelling the monotonic flexural response of RC jacketed columns

2021

Abstract The use of reinforced concrete (RC) jacketing is a common technique for retrofitting existing RC columns with poor structural performances. Literature studies highlighted that the relative slip occurring at the interface between the new and the old concrete can affect substantially the flexibility and the strength of the retrofitted member. For this reason, several interface treatments are usually applied, aiming to induce a monolithic behaviour to the column. However, despite the commonness of RC jacketing, a limited number of studies investigated numerical modelling strategies for including these phenomena, especially with reference to the development of numerical models for desi…