Search results for "FLIP"

showing 10 items of 133 documents

Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance

2022

Background & Aims Serum microRNA (miRNA) levels are known to change in non-alcoholic fatty liver disease (NAFLD) and may serve as useful biomarkers. This study aimed to profile miRNAs comprehensively at all NAFLD stages. Methods We profiled 2,083 serum miRNAs in a discovery cohort (183 cases with NAFLD representing the complete NAFLD spectrum and 10 population controls). miRNA libraries generated by HTG EdgeSeq were sequenced by Illumina NextSeq. Selected serum miRNAs were profiled in 372 additional cases with NAFLD and 15 population controls by quantitative reverse transcriptase PCR. Results Levels of 275 miRNAs differed between cases and population controls. Fewer differences were seen wi…

SCORING SYSTEMCPM counts per millionAUROC area under the receiver operating characteristicRC799-869AST aspartate aminotransferaseMicroRNA; Non-alcoholic fatty liver disease; Biomarker; SequencingTGF-β transforming growth factor-betaGastroenterologySTEATOHEPATITISLiver disease0302 clinical medicineFibrosismiRNA microRNAlogFC log2 fold changeFIBROSISImmunology and AllergySequencing0303 health scienceseducation.field_of_studyNAS NAFLD activity scoremedicine.diagnostic_testFatty liverGastroenterologyGTEx Genotype-Tissue ExpressionMicroRNADiseases of the digestive system. Gastroenterology3. Good healthReal-time polymerase chain reactionBiomarker MicroRNA Non-alcoholic fatty liver disease SequencingLiver biopsyACIDBiomarker (medicine)030211 gastroenterology & hepatologyLife Sciences & BiomedicineResearch ArticleEXPRESSIONmedicine.medical_specialtyNAFLD non-alcoholic fatty liver diseaseNASH non-alcoholic steatohepatitisPopulationGastroenterology and HepatologySAF steatosis–activity–fibrosisVALIDATIONER endoplasmic reticulum03 medical and health sciencescDNA complementary DNAInternal medicineALT alanine aminotransferaseGastroenterologiInternal MedicinemedicineNAFL non-alcoholic fatty liverALGORITHMFIB-4 fibrosis-4education030304 developmental biologyPCA principal component analysisScience & TechnologyGastroenterology & HepatologyHepatologybusiness.industryBiomarkerFC fold changemedicine.diseaseBiomarker; MicroRNA; Non-alcoholic fatty liver disease; Sequencingdigestive system diseasesFLIP fatty liver inhibition of progressionCt cycle thresholdSteatosisqPCR quantitative PCRbusinessNon-alcoholic fatty liver disease
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Prefazione

2022

Settore L-FIL-LET/15 - Filologia Germanicaflipped teaching glottodidattica metodi situazionale e nozionale-funzionale classe capovolta
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Motivare attraverso la flipped classroom

2016

All'interno dell'articolo si sottolinea come la flipped classroom permetta di sfruttare le opportunità offerte dalle ICT e dai linguaggi digitali per supportare nuovi modi di insegnare, apprendere e motivare. Essa consente, da un lato, al docente di svolgere il delicato compito di scegliere accuratamente il materiale multimediale che intende adottare per la classe e, dall'altro, di motivare gli alunni ad apprendere, stimolarli a riflettere ed approcciarsi alle nuove tecnologie con maggiore senso critico, sviluppando capacità di selezione dei dati e delle informazioni in maniera autonoma.

Settore M-PED/04 - Pedagogia SperimentaleFlipped classroom motivazione insegnamento apprendimento
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Radiative 2D Shocks, Super-Eddington Disks and Jets around Black Holes

2005

It is well known that rotating inviscid accretion flows with adequate injection parameters around black holes could form shock waves close to the black holes, after the flow passes through the outer sonic point and can be virtually stopped by the centrifugal force. Such shock waves in 2D accretion flows are examined by 2D radiation hydrodynamical calculations. We also examine super‐Eddington accretion disks with 15 ṀE around black holes, focusing on a small collimation degree of the jet and a large mass‐outflow rate observed in the X‐ray source SS 433.

Shock wavePhysicsGeneral Relativity and Quantum CosmologyBinary black holeIntermediate-mass black holeAstrophysics::High Energy Astrophysical PhenomenaRadiative transferStellar black holeAstrophysicsSpin-flipAstrophysics::Galaxy AstrophysicsGamma-ray burst progenitorsAccretion (astrophysics)AIP Conference Proceedings
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Flip angle considerations in (3)helium-MRI.

2000

3Helium-MRI ((3)He-MRI) can be used for analysis of lung function, e. g. dynamic imaging of ventilation and gas diffusion within the lung, assessment of intrapulmonary oxygen concentrations and their time course. During imaging, the irreversible signal loss due to depolarizing radio frequency excitations can be described using the flip angle (FA) alpha. This parameter has to be quantified in order to account for it during quantitative assessment of the (3)helium signal intensity and its temporal development. This technical report reviews two different methods to determine alpha. Limitations and possible error sources of each method are discussed.

Signal processingMaterials sciencemedicine.diagnostic_testEstimation theoryDynamic imagingMagnetic resonance imagingSignalHeliumMagnetic Resonance ImagingRespiratory Function TestsOxygenNuclear magnetic resonanceFlip angleIsotopesmedicineTidal VolumeMolecular MedicineHumansRadiology Nuclear Medicine and imagingComputer SimulationRadio frequencyHyperpolarization (physics)SpectroscopyNMR in biomedicine
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Spin relaxation in Cu and Al spin conduits

2014

We study the spin relaxation in Al and Cu spin conduits embedded in non-local spin valve nanostructures. Measuring the key spin transport properties, we determine the spin and charge diffusion constants as well as the spin flip time. By varying the temperature, we find that the maximum of the non-local spin resistance change occurs at finite temperatures with a clear difference between Al and Cu. In particular, we find that the maximum of the non-local spin signal in Al is less pronounced and occurs at lower temperatures compared to Cu suggesting that the self-passivating Al surface plays a role. Having fabricated devices with both materials in identical processes, we can attribute the diff…

Spin polarizationCondensed matter physicsChemistrySpin valveSurfaces and InterfacesZero field splittingCondensed Matter PhysicsSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsSpin iceSpin waveMaterials ChemistryCondensed Matter::Strongly Correlated ElectronsSpin-flipElectrical and Electronic EngineeringQuantum spin liquidSpin-½physica status solidi (a)
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Informational rigidity in mesitylene-based calix[4]arenes adopting a 1,3-alternate conformation

2000

Abstract Two chiral derivatives of a mesitylene-based calix[4]arene known to exist in the 1,3-alternate conformation were prepared by the attachment of homochiral residues to the four exo -hydroxy groups. Thus, the enantiotopic protons of the central scaffold became diastereotopic, leading to a doubling of their 1 H NMR signals in one example. From the temperature independence of the NMR spectrum, a lower limit of 24.2 kcal/mol could be estimated for the barrier of ring inversion. MM3 calculations confirm the 1,3-alternate conformation as the energy minimum, and estimate a barrier of 25.7 kcal/mol for the 1,3-alternate-to-1,3-alternate* interconversion process. This high barrier is due to t…

Steric effectsRing flipStereochemistryChemistryOrganic ChemistryNuclear magnetic resonance spectroscopyCatalysisInorganic Chemistrychemistry.chemical_compoundEnergy minimumRigidity (electromagnetism)Proton NMRPhysical and Theoretical ChemistryMesityleneVicinalTetrahedron: Asymmetry
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Web tools per promuovere l’apprendimento collaborativo nella formazione iniziale dei futuri insegnanti

2017

L’approccio flipped può risultare una valida proposta didattica in quanto promuove le forme collaborative di apprendimento. L’apprendimento collaborativo, che trova le sue radici nella teoria socioculturale e nella teoria sociocognitiva, per decenni è stato un pilastro della formazione negli USA. Attraverso il lavoro di ricerca si è voluto descrivere lo sviluppo della competenza digitale nei futuri insegnanti, promuovendo al contempo lo spirito collaborativo e la capacità di mobilitazione delle proprie risorse cognitive, emotive e creative. Si è inteso altresì osservare e rilevare il grado di collaborazione, la capacità di richiedere aiuto, l’ impegno motivato e la costanza dei futuri inseg…

TIC classe capovolta apprendimento collaborativo formazione inizialeICT flipped classroom collaborative learning initial teacher educationSettore M-PED/03 - Didattica E Pedagogia Speciale
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"Clase al revés". Nuevos escenarios en la formación didácticotecnológica de docentes de un Centro de Educación Especial.

2016

El uso de las TIC en educación está creciendo con el fin de mejorar y actualizar las metodologías didácticas para que se adapten tanto a la sociedad del conocimiento como a las capacidades e intereses de los estudiantes, a sus lenguajes de comunicación y a nuevas maneras de aprender (Jenkins, 2013). En ese contexto de evolución y cambio, las TIC se configuran como tecnologías inclusivas abriendo las posibilidad de innovación del sistema educativo también con aquellos estudiantes que presentan necesidades educativas especiales (n.e.e.) asociadas a algún tipo de discapacidad. La formación del profesorado supone por ello un elemento de primer orden (EADSNE, 2013). En ese sentido, investigadore…

TIC formación del profesorado discapacidad intelectual educación especial flipped classroom.
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E-portfolio e flipped classroom: un’indagine esplorativa con i futuri insegnanti di scuola primaria

2023

Il contributo intende far riflettere sul tema della formazione dei futuri insegnanti di scuola primaria, a partire dall’impiego dell’e-portfolio come dispositivo innovativo per promuovere l’acquisizione della competenza riflessiva e autovalutativa all’interno della flipped classroom. La ricerca, che ha coinvolto 154 studenti del Corso di laurea magistrale in Scienze della Formazione Primaria dell’Università degli Studi di Palermo, che frequentavano il corso di Docimologia nell’anno accademico 2020/2021, presenta i presupposti teorici, gli obiettivi e le modalità operative di un percorso che ha visto l’impiego dell’e-portfolio nella flipped per promuovere lo sviluppo delle competenze docimol…

The study aims to reflect on the training of future primary school teachers by starting from the use of the e-portfolio as an innovative tool to promote the acquisition of reflective and self-evaluation competence within the flipped classroom. The research involved 154 students of Primary Education Master’s Degree Course of the University of Palermo attending to the Docimology course during the academic year 2020/2021. This paper presents the theoretical assumptions objectives and operating methods of a path that made the use of the e-portfolio in flipped classroom to promote the development of docimological skills in higher education. It was hypothesized that the training intervention designed according to the principles of the flippmethodology and through the use of the e-portfolio would have contributed to the development of students’ self-evaluation skills during the 30 hours of the Docimology course.Settore M-PED/04 - Pedagogia Sperimentale
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