Flip angle considerations in (3)helium-MRI.

6533b823fe1ef96bd127eba2

RESEARCH PRODUCT

Flip angle considerations in (3)helium-MRI.

Norbert Weiler Balthasar Eberle Hans-ulrich Kauczor Manfred Thelen Wolfgang Schreiber Klaus Markstaller

subject

Signal processing Materials science medicine.diagnostic_test Estimation theory Dynamic imaging Magnetic resonance imaging Signal Helium Magnetic Resonance Imaging Respiratory Function Tests Oxygen Nuclear magnetic resonance Flip angle Isotopes medicine Tidal Volume Molecular Medicine Humans Radiology Nuclear Medicine and imaging Computer Simulation Radio frequency Hyperpolarization (physics)Spectroscopy

description

3Helium-MRI ((3)He-MRI) can be used for analysis of lung function, e. g. dynamic imaging of ventilation and gas diffusion within the lung, assessment of intrapulmonary oxygen concentrations and their time course. During imaging, the irreversible signal loss due to depolarizing radio frequency excitations can be described using the flip angle (FA) alpha. This parameter has to be quantified in order to account for it during quantitative assessment of the (3)helium signal intensity and its temporal development. This technical report reviews two different methods to determine alpha. Limitations and possible error sources of each method are discussed.

year	journal	country	edition	language
2000-06-27	NMR in biomedicine

https://pubmed.ncbi.nlm.nih.gov/10867695

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