Search results for "FLP"

showing 10 items of 63 documents

Evoluzione della popolazione blastomicetica durante la produzione di olive da tavola di differenti cultivar siciliane monitorata attraverso l’analisi…

2008

La popolazione blastomicetica di olive verdi da tavola, prodotte a partire da 4 diverse cultivar siciliane (Brandofino, Castriciana, Nocellara del Belice, Passulunara) e da una spagnola (Manzanilla), è stata monitorata durante l’intero processo di fermentazione. La tecnologia produttiva poteva definirsi di tipo semi-industriale, giacché il ruolo della microflora lattica era parzialmente sostituito dall’aggiunta di acido lattico e la fermentazione naturale avveniva in salamoia all’8% di NaCl. La popolazione di lieviti all’avvio del processo fermentativo è risultata, indipendentemente dalla cultivar di appartenenza, nell’ordine di 2.0 log UFC g-1. Viceversa nel prodotto al consumo le conte ha…

ITS-RFLPOlive da tavolaOlive verdi da tavola SicilianeIdentificazioneSiciliaPichia kluyveriLievitiComunità blastomiceticaSettore AGR/16 - Microbiologia Agraria
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SARS CoV2 infection _The longevity study perspectives

2021

Graphical abstract

MaleAgingssRNA single-stranded RNARFLP restriction fragment length polymorphismHSPs heat shock proteinsReviewPTMs post-translational modificationsSevere Acute Respiratory SyndromeBiochemistryHIV-1 human immunodeficiency virus-1TNF-α tumor necrosis factor-αEC endothelial cells0302 clinical medicineFluAV influenza A virusI insertionMedicineIFN-γ interferon-γDIC disseminated intravascular coagulationPCR Polymerase Chain Reactionmedia_commonAged 80 and overLongevityRBD receptor-binding domainNeurologyLongevity modelMI myocardial infarctionNK natural killerhPIV2 human parainfluenza virus type 2media_common.quotation_subjectResearching genetic basis of resistance and potential pharmacological targetsLongevityDBP diastolic blood pressureNF-Kb nuclear transcription factor kBRANTES regulated upon activation normal T cell expressed and secretedMphi human macrophages03 medical and health sciencesCox 2 cyclooxygenase 2ORF open reading framePT prothrombin timeSettore MED/05 - Patologia ClinicaHumansMolecular BiologyInflammatory genesARDS acute respiratory distress syndromeNO nitric oxideD deletionCpGIs CpG islandsT2DM type 2 diabetes mellitusmedicine.diseaseFDP fibrin degradation products030104 developmental biologySARS CoV2 severe acute respiratory syndrome Coronavirus 2 virusImmunologyBMI body max indexItalian nonagenarians/centenariansRSV respiratory syncytial virusComplication030217 neurology & neurosurgeryMAPK mitogen-activated protein kinaseIP-10 IFN-γ -Inducible Protein 1040301 basic medicineAT1R activity of angiotensin 1 receptorsDCs dentritic cellsSSCP single strand conformation polymorphismACE/DD polymorphism of the angiotensin converting enzymeFGF21 fibroblast growth factor 21TLR4 toll-like receptor 4NAD nicotinamide adenine dinucleotideACE angiotensin-I converting enzymeAT2R activity of angiotensin 2 receptorsCOVID-19 Coronavirus disease 2019Respiratory distressACE2 angiotensin converting enzyme 2MKP-1 mitogen-activated protein kinase phosphatase-1 ()PD protease domainSNP single nucleotide polymorphismEH essential hypertensionTNFR tumor necrosis factor receptorINR international normalized ratio of the prothrombin timePAI-1 plasminogen activator inhibitor-1Ang angiotensinLPS lipopolysaccharideMCP1 monocyte chemoattractant protein-1medicine.symptomaPTT partial thromboplastin timeBiotechnologyDUSP1 dual specificity phosphatase 1Coronavirus disease 2019 (COVID-19)PC prostate cancerRAS renin-angiotensin aldosterone systemCCR5Δ32 genetic variant of chemokine receptorCOVID-19 Researching genetic basis of resistance and potential pharmacological targets Italian nonagenarians/centenarians Longevity modelAsymptomaticSARS-1 severe acute respiratory syndrome virus 1SIRT-1 Sirtuin 1Th1 t-helper lymphocyte type 1Immune systemROS reactive oxygen speciesTGF-β transforming growth factor betaET-1 endothelin-1ComputingMethodologies_COMPUTERGRAPHICSADAM-17 metallopeptidase domain 17business.industrySARS-CoV-2SBP systolic blood pressureCOVID-19HDACs histone deacetylasesComorbidityImmune Systembusiness5-LO lipoxygenase 5Ageing Research Reviews
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Further investigations on populations of the deep-water blue and red shrimp Aristeus antennatus (Risso, 1816) (Decapoda, Dendrobranchiata), as inferr…

2012

The aim of this study was to integrate existing mitochondrial DNA data relating to the deep-sea blue and red shrimp Aristeus antennatus (Risso, 1816) with data obtained by Amplified Fragment Length Polymorphism (AFLP). A total of 145 AFLP polymorphic loci were scored in 236 specimens collected from one Atlantic and seven Mediterranean sample sites. AMOVA results revealed that the overall genetic variation among-populations was lower (11.81%) than within-populations (88.19%). The genetic variation between the Atlantic and Mediterranean samples was found to be not significant ( Φ CT = − 0 . 007 ; N.S.), indicating that the transition area between the Atlantic Ocean and the Mediterranean Sea d…

Mediterranean climateAFLPAFLP; Area atlanto-mediterranea; Aristeus antennatus; Atlanto-Mediterranean region; mtDNAfood.ingredientbiologymtDNADecapodaEcologyArea atlanto-mediterraneaSettore BIO/05 - ZoologiaZoologyDendrobranchiataAquatic ScienceAtlanto-Mediterranean regionbiology.organism_classificationMediterranean BasinAristeus antennatuShrimpMediterranean seafoodGenetic variationAnimal Science and ZoologyAmplified fragment length polymorphismCrustaceana
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Seasonal trend of Anisakidae infestation in South Mediterranean bluefish

2020

A total of 1104 fish samples from markets of Sicily were analysed for the detection and species identification of Anisakidae nematodes. The preliminary analysis of the fish samples showed the presence of 2459 larvae. All the fish species revealed different prevalence of infestation, with a maximum of 100% for Lepidopus caudatus and a minimum of 4.5% in Sardina pilchardus. The 80% of the larvae examined by PCR-RFLP analysis belonged to Anisakis pegreffii species. The seasonal infestation trend of Anisakis was evaluated in all the fish sample examined. The results of the seasonal infestation trend showed a marked connection with the ecological aspects of the fish species examined. As far as w…

Mediterranean climateLepidopus caudatusNematodaFishingZoologyPlant Sciencemedicine.disease_causeAnisakiasismorphological identification01 natural sciencesBiochemistryAnisakisPolymerase Chain ReactionAnalytical ChemistryAnisakis pegreffiiFish DiseasesPCR-RFLPFood ParasitologyInfestationmedicineMediterranean SeaPrevalenceAnimalsSicilyLarvabiologyspp.010405 organic chemistryOrganic ChemistryFishesbiology.organism_classificationAnisakisspp0104 chemical sciencesPerciformes010404 medicinal & biomolecular chemistryAnisakidaeSeafoodspp.; PCR-RFLP; morphological identification; prevalence of infestationSeasonsprevalence of infestation
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Advanced Strategies for Food-Grade Protein Production: A New E. coli/Lactic Acid Bacteria Shuttle Vector for Improved Cloning and Food-Grade Expressi…

2019

Food-grade production of recombinant proteins in Gram-positive bacteria, especially in LAB (i.e., Lactococcus, Lactobacillus, and Streptococcus), is of great interest in the areas of recombinant enzyme production, industrial food fermentation, gene and metabolic engineering, as well as antigen delivery for oral vaccination. Food-grade expression relies on hosts generally considered as safe organisms and on clone selection not dependent on antibiotic markers, which limit the overall DNA manipulation workflow, as it can be carried out only in the expression host and not in E. coli. Moreover, many commercial expression vectors lack useful elements for protein purification. We constructed a &ld…

Microbiology (medical)Lactococcusfood-grade expression vectorsBiologyMicrobiologylaw.inventionMetabolic engineering03 medical and health sciencesShuttle vectorresistance cassette removallawVirologyProtein purificationlcsh:QH301-705.5Gene030304 developmental biology0303 health sciencesExpression vector030306 microbiologyfood and beveragesbiology.organism_classificationgenerally recognized as safe (GRAS) microorganismsshuttle expression vectorslcsh:Biology (General)BiochemistryRecombinant DNAadvanced food-grade cloning: flippase (FLP) recombinaselactic acid bacteria (LAB)BacteriaMicroorganisms
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A polyphasic approach to the identification of ochratoxin A-producing black Aspergillus isolates from vineyards in Sicily.

2008

Aspergillus strains belonging to section Nigri isolated during a two year survey in eight Sicilian vineyards located on the slopes of Mount Etna (Sicily, Italy) were analysed analyzed in order to characterize species responsible for ochratoxin A (OTA) contamination of grapes. The polyphasic approach permitted analysis of biodiversity of Aspergillus isolates in relation to their morphology, ochratoxigenicity and genetic variability. We assessed OTA production by A. carbonarius, A. niger, A. tubingensis and A. japonicus using an enzyme-linked immunosorbent assay. A. carbonarius isolates were the strongest OTA producers. A subset of 66 representative strains was selected for further DNA-based …

Ochratoxin AVeterinary medicineEnzyme-Linked Immunosorbent AssayFood ContaminationfAFLPMicrobiologylaw.inventionMicrobiologychemistry.chemical_compoundVineyard OTA A. carbonariusPCR identificationSpecies SpecificitylawDNA Ribosomal SpacerCluster AnalysisVitisGenetic variabilityDNA FungalOchratoxinAspergillus; Ochratoxin A; fAFLP; PCR identification; 16s rDNA sequencingPolymerase chain reactionPhylogenyAspergillusbiology16s rDNA sequencingAspergillus nigerOchratoxin AGeneral MedicineFungi imperfectiSequence Analysis DNAbiology.organism_classificationOchratoxinsRNA Ribosomal 5.8SAspergilluschemistryItalyAspergillus nigerRestriction fragment length polymorphismPolymorphism Restriction Fragment LengthFood ScienceInternational journal of food microbiology
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VEGFR-3 and CXCR4 as predictive markers for treatment with fluorouracil, leucovorin plus either oxaliplatin or cisplatin in patients with advanced es…

2014

Abstract Background Combination of fluoropyrimidines and a platinum derivative are currently standards for systemic chemotherapy in advanced adenocarcinoma of the stomach and gastroesophageal junction (GEJ). Nevertheless, individual likelihood for response to these therapeutic regimes remains uncertain. Even more, no predictive markers are available to determine which patients may benefit more from oxaliplatin versus cisplatin or vice versa. The new invasion and stem cell markers VEGFR-3 and CXCR4 have been linked prognostically with more aggressive esophagogastric cancer types. Thus, we aimed to assess correlations of VEGFR-3 and CXCR4 expression levels with clinical outcome in a randomize…

OncologyMaleCancer ResearchOrganoplatinum Compoundsmedicine.medical_treatmentLeucovorinSurgical oncologyAntineoplastic Combined Chemotherapy ProtocolsAged 80 and overeducation.field_of_studyAdvanced esophagogastric cancerMiddle AgedPrognosisImmunohistochemistryOxaliplatinTreatment OutcomeOncologyFluorouracilAdenocarcinomaFemaleEsophagogastric JunctionFluorouracilmedicine.drugResearch ArticleAdultmedicine.medical_specialtyReceptors CXCR4FLOFLPPopulationStomach NeoplasmsInternal medicinemedicineGeneticsHumanseducationSurvival analysisAgedNeoplasm StagingCisplatinCXCR4Chemotherapybusiness.industrymedicine.diseaseVascular Endothelial Growth Factor Receptor-3OxaliplatinVEGFR-3CisplatinbusinessBiomarkersBMC Cancer
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Molecular diagnostic tools for the detection and characterization of Phoma tracheiphila

2011

In the recent years PCR-based techniques for the identification and detection of Phoma tracheiphila, the causal agent of citrus mal secco disease, have been evaluated aiming to provide tools for biological and epidemiological studies. A wide collection of P. tracheiphila strains was used to evaluate and validate diagnostic protocols and a fAFLP method for fungal characterization. Conventional and real-time PCR protocols were successfully tested for the specific identification of P. tracheiphila and its detection in planta. A further improvement of the real-time PCR protocol and the DNA extraction methods allowed the quantification of the fungus both from naturally infected and artificially …

Phoma tracheiphilalemonquantitative PCRCitruSettore AGR/12 - Patologia VegetaleComputational biologyHorticultureBiologyfAFLPDiagnostic toolsbiology.organism_classification"mal secco" disease
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Space-time Point Processes semi-parametric estimation with predictive measure information

2014

In this paper, we provide a method to estimate the space-time intensity of a branching-type point process by mixing nonparametric and parametric approaches. The method accounts simultaneously for the estimation of the different model components, applying a forward predictive likelihood estimation approach to semi-parametric models.

Point Process.etasFLPNonparametric EstimationForward Predictive Likelihood
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Does a specific genetic background influence endurance or power-orientated phenotypes?

2012

The purpose of this study was to determine the probability of individuals having the “best” mitochondrial biogenesis related polygenic profile that could increase performance. We compared polygenic profile analyzing several polymorphisms on sixty professional italian soccer players, considered “power-oriented athletes” and thirty sedentary volunteers. Samples of venous blood were obtained by standard clinical procedures and anticoagulant-treated blood was used to prepare genomic DNA. The polymorphic sites were scanned using PCR-RFLP protocols with different enzyme. Furthermore, a cloted part of venus blood sample was used to obtain serum from which we analyzed total cholesterol, high densit…

Polygenic profilesoccer playersPCR-RFLPSettore BIO/10 - Biochimica
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