Search results for "FN"

Landelinus, l’auteur de la plaque-boucle mérovingienne au Christ de l’Apocalypse découverte à Ladoix-Serrigny (Côte-d’Or) serait-il saint Landeli…

2021

Cette note concerne l’exceptionnelle plaque-boucle au Christ cavalier de l’Apocalypse découverte à Ladoix-Serrigny et étudiée précédemment dans cette revue. Son objectif est de discuter l’hypothèse récemment émise selon laquelle saint Landelin, qui a vécu au VIIe siècle dans le nord de la Gaule, serait Landelinus, l’auteur de cet objet. Plusieurs arguments militent en faveur de cette interprétation qui nous paraît donc plausible, même si elle reste fragile. Il est également envisagé de localiser cette fabrication dans le prestigieux monastère de Luxeuil. Mais il s’agit là encore d’une hypothèse. This note concerns the exceptional buckle-plate to the Christ cavalier of the Apocalypse discove…

Ohjaava opetuskeskustelu suomalaisella viittomakielellä : tapaustutkimus kuuron oppilaan matematiikan opetuksesta

2014

Suomalaisen viittomakielen pro gradu –työssäni tarkastelen kuuron oppilaan viittomakielistä opetusta vuorovaikutuksen näkökulmasta. Tutkimusaineisto koostuu kahdesta matematiikan yksilöopetustunnista. Tutkimuksen tavoitteena on ollut selvittää, millaisia muotoja ohjaava opetuskeskustelu saa kuuron oppilaan suomalaisella viittomakielellä toteutetussa opetuksessa. Tapaustutkimuksen kautta yksilöidään ja luokitellaan myös viittomakielisen ohjaavan opetuskeskustelun osatekijöitä. Tutkimusaineiston analyysi perustuu Vygotskyn (1978) sosiokulttuuriseen teoriaan ja siihen liittyviin käsitteisiin oppimisen oikea-aikainen tukeminen ja lähikehityksen vyöhyke. Videotaltiointien analy…

P10.07 PERINDOPRIL THERAPY IMPROVES ENDOTHELIAL FUNCTION AND ARTERIAL STIFFNESS IN HEART FAILURE WITH PRESERVED SYSTOLIC FUNCTION

2010

NPM-ALK-reactive T-cell responses in children and adolescents with NPM-ALK positive anaplastic large cell lymphoma

2019

ABSTRACT The oncoantigen nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) induces cellular and humoral immune responses in patients with NPM-ALK-positive anaplastic large cell lymphoma (ALCL). We characterize the NPM-ALK-specific T-cell responses in a cohort of pediatric and adolescent ALCL-patients in remission without Human Leucocyte Antigen (HLA)-preselection. First, we assessed NPM-ALK-reactive T-cell responses and their HLA-class I restriction in patients by using dendritic cells (DCs) transfected with in vitro transcribed (IVT) NPM-ALK-RNA for CD8 (n = 20) or CD3 (n = 9) T-cell stimulation. NPM-ALK-specific T-cells were detected in twelve of 29 patients (nine of 20 with CD8-selected…

Azithromycin Differentially Alters TCR-Activated Helper T Cell Subset Phenotype and Effector Function

2020

In addition to their antibiotic activities, azithromycin (AZM) exhibits anti-inflammatory effects in various respiratory diseases. One of the potent anti-inflammatory mechanisms is through inhibition of CD4+ helper T (Th) cell effector function. However, their impact on specific Th subset is obscure. Herein, we demonstrate the cellular basis of phenotypic and functional alterations associated with Th subsets following AZM treatment in vitro. Using well-characterized Th subset specific chemokine receptors, we report significant suppression of T cell receptor (TCR)-stimulated hyperactivated CCR4+CXCR3+ (Th0) expansion compared to CCR4-CXCR3+ (Th1-like) and CCR4+CXCR3- (Th2-like) cells. Intere…

Análisis molecular de la valoración del intervalo de tiempo óptimo entre la administración de acetato de triptorelina y la punción folicular en los t…

2023

Los fármacos análogos de la GnRH y la hCG han demostrado ser igualmente eficaces en la activación de la cascada de intermediarios de la maduración final ovocitaria que ocurre tras el estímulo ovulatorio. Sin embargo, su mecanismo de acción y por tanto los perfiles hormonales hallados tras el estímulo de los dos fármacos son muy diferentes. El tiempo más adecuado para programar la recolección ovocitaria tras la administración de acetato de triptorelina podría no ser 36 horas como ampliamente se ha pautado en los tratamientos de FIV con hCG. Este intervalo de tiempo es sumamente importante para obtener la mayor proporción posible de ovocitos MII porque procesos como el inicio de la luteinizac…

Mediterranean diet impact on cardiovascular diseases: a narrative review

2017

Cardiovascular disease (CVD) accounts for more than 17 million deaths per year worldwide. It has been estimated that the influence of lifestyle on CVD mortality amounts to 13.7% for smoking, 13.2% for poor diet, and 12% for inactive lifestyle. These results deeply impact both the healthy status of individuals and their skills in working. The impact of CVD on productivity loss accounts for the 24% in total costs for CVD management. Mediterranean diet (MedD) can positively impact on natural history of CVD. It is characterized by a relatively high consumption of inexpensive and genuine food such as cereals, vegetables, legumes, nuts, fish, fresh fruits, and olive oil as the principal source of…

Focal liver lesions in patients with cavernous transformation of the portal vein: diagnosis and MR features.

2008

The Immunostimulatory Function of IL-12 in T-Helper Cell Development and Its Regulation by TGF-β, IFN-γ and IL-4

1997

Functional Near Infrared Spectroscopy System Validation for Simultaneous EEG-FNIRS Measurements

2019

Functional near-infrared spectroscopy (fNIRS) applied to brain monitoring has been gaining increasing relevance in the last years due to its not invasive nature and the capability to work in combination with other well–known techniques such as the EEG. The possible use cases span from neural-rehabilitation to early diagnosis of some neural diseases. In this work a wireline FPGA–based fNIRS system, that use SiPM sensors and dual-wavelength LED sources, has been designed and validated to work with a commercial EEG machine without reciprocal interference.