Search results for "FN"

showing 10 items of 862 documents

A biomechanical evaluation of methods of distal humerus fracture fixation using locking compression plates versus conventional reconstruction plates.

2004

OBJECTIVES To examine the biomechanical behavior of 2 techniques of double-plate osteosynthesis for fractures of the adult distal humerus using conventional reconstruction plates and locking compression plates. DESIGN Basic science study. SETTING Experimental in vitro study. PATIENTS/PARTICIPANTS Forty fresh-frozen human distal humeri specimens. INTERVENTION Four matched groups with 10 humeri each, median age 74 years (46-95), were created using similar bone mineral density values. Two standard configurations of double-plate osteosynthesis (dorsal or 90 degrees configuration) with either conventional reconstruction plates or locking compression plates were studied for biomechanical properti…

medicine.medical_specialtyHumeral Fracturesmedicine.medical_treatmentOsteotomyFracture Fixation InternalFracture fixationBone plateMaterials TestingmedicineHumansOrthopedics and Sports MedicineHumerusAgedBone mineralOrthodonticsAged 80 and overOsteosynthesisbusiness.industryBiomechanicsStiffnessGeneral MedicineEquipment DesignMiddle AgedSurgeryBiomechanical Phenomenamedicine.anatomical_structureSurgerymedicine.symptombusinessBone PlatesJournal of orthopaedic trauma
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Bowel resection reduces aortic pulse wave velocity in patients with ulcerative colitis. A longitudinal study.

2020

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medicine.medical_specialtyLongitudinal studySettore MED/09 - Medicina Internamedicine.medical_treatmentInflammationBlood PressurePulse Wave AnalysisInflammatory bowel diseaseGastroenterologyInflammatory bowel diseaseVascular StiffnessInternal medicineInternal MedicinemedicineHumansIn patientLongitudinal StudiesPulse wave velocityArterial stiffness Inflammation Inflammatory bowel disease Pulse wave velocity Blood Flow Velocity Blood Pressure Humans Longitudinal Studies Pulse Wave Analysis Colitis Ulcerative Vascular StiffnessInflammationbusiness.industryBowel resectionmedicine.diseaseUlcerative colitisArterial stiffnessPulse wave velocityArterial stiffnessColitis Ulcerativemedicine.symptombusinessBlood Flow VelocityEuropean journal of internal medicine
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Relationship between metabolic syndrome and aortic stiffness in untreated hypertensive patients

2005

medicine.medical_specialtyMean arterial pressureAmbulatory blood pressurebusiness.industrymedicine.diseaseBlood pressureDiabetes mellitusInternal medicineHeart rateInternal MedicinemedicineCardiologyAortic stiffnessMetabolic syndromebusinessPulse wave velocityAmerican Journal of Hypertension
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Evaluation of nitroglycerin effect on remote photoplethysmogram waveform acquired at green and near infra-red illumination

2017

Assessment of skin microcirculation provides diagnostically valuable information during the early stages of pathologies. The simple, cost-effective and intrusive alternative to existing circulation assessment methods is remote photoplethysmography (rPPG). The objective of the present pilot study was to reveal an effect on sublingual administration of 1 mg nitroglycerin on systemic hemodynamic parameters and rPPG waveforms, at 810 nm and 530nm illumination. The protocol comprised 3 minutes of baseline recording, 15 minutes recording of NTG effect, 2 minutes of arterial occlusion and the following 3 min reactive hyperemia. Two PPG signals were acquired from glabrous skin of the middle finger …

medicine.medical_specialtyMean arterial pressurebusiness.industryHemodynamicsmedicine.diseaseArterial occlusionSublingual administrationInternal medicinePhotoplethysmogramHeart rateCardiologyArterial stiffnessMedicinebusinessReactive hyperemiaBiophotonics—Riga 2017
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New approaches in the treatment of Adamantiades-Behçet's disease.

2005

Purpose of review To update clinicians on the recent advances in the treatment of Adamantiades-Behcet's disease. Recent findings Interferon-α-2a and infliximab have proved able to induce prompt remission in the vast majority of Adamantiades-Behcet's patients with DMARD-resistant uveoretinitis. Efficacy of interferon-α-2a has also been reported for mucocutaneous lesions, arthritis, and (more anecdotally) for neuro-Behcet, while results from small case series suggest that infliximab is beneficial for mucocutaneous lesions and (more anecdotally) for arthritis and gastro-intestinal manifestations. Two cases of neuro-Behcet treated with infliximab showed a complete resolution. Finally, in a rand…

medicine.medical_specialtyMucocutaneous zoneArthritisBehcet's diseaseDiseaseInterferon alpha-2Receptors Tumor Necrosis Factorlaw.inventionEtanerceptEtanerceptRheumatologyRandomized controlled triallawAntibodies Monoclonal; Behcet Syndrome; Chaperonin 60; Humans; Immunoglobulin G; Immunologic Factors; Interferon-alpha; Receptors Tumor Necrosis Factor; Recombinant ProteinsmedicineHumansImmunologic FactorsIFN-α2abusiness.industryBehcet SyndromeAntibodies MonoclonalInterferon-alphaChaperonin 60medicine.diseaseDermatologyeye diseasesInfliximabAdamantiades-Behçet's diseaseInfliximabRecombinant Proteinsstomatognathic diseasesImmunoglobulin GImmunologyTumour necrosis factorbusinessTolerizationUveitismedicine.drugCurrent opinion in rheumatology
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2018

Background The aim of our study was to evaluate the feasibility of exercise cardiac magnetic resonance (CMR) in patients with repaired tetralogy of Fallot (RTOF) and to assess right and left ventricular adaptation and aortic wall response to exercise in comparison with volunteers. Methods 11 RTOF and 11 volunteers underwent prospective CMR at rest and during exercise. A supine bicycle ergometer was employed to reach twice the resting heart rate during continuous exercise, blood pressure and heart rate were recorded. Bi-ventricular parameters and aortic stiffness were assessed using accelerated cine sequences and flow-encoding CMR. A t-test was used to compare values between groups. A Mann W…

medicine.medical_specialtyMultidisciplinaryEjection fractionbusiness.industryHemodynamics030204 cardiovascular system & hematologymedicine.disease030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineBlood pressureInternal medicinemedicine.arteryHeart rateAscending aortacardiovascular systemCardiologyMedicineAortic stiffnessExercise physiologybusinessTetralogy of FallotPLOS ONE
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2021

IntroductionWork-life conflicts (WLC) may impact health, but few studies prospectively consider the impact of WLC on objective outcomes such as cardiovascular disease. Using data from the Gutenberg Health Study (GHS), we examined if WLC at baseline was associated with an increased five-year incidence of cardiovascular events (myocardial infarct, stroke, atrial fibrillation, peripheral artery disease, coronary artery disease, chronic heart failure, sudden cardiac death). We also considered if WLC was associated with incident hypertension and arterial stiffness and if the effects of WLC on cardiovascular health differ for men and women.MethodsA working subsample of the 15,010 GHS cohort parti…

medicine.medical_specialtyMultidisciplinaryProportional hazards modelbusiness.industryHazard ratiomedicine.diseaseCoronary artery diseasesymbols.namesakeBlood pressureRelative riskInternal medicineCohortArterial stiffnessmedicinesymbolsPoisson regressionbusinessPLOS ONE
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Cardiac biomarkers and arterial stiffening: data from the Gutenberg Health study

2013

medicine.medical_specialtyMyocardial ischemiabusiness.industryCardiac biomarkersmedicine.diseaseStiffeningMultiple Endocrine Neoplasia Type 2aInternal medicineArterial stiffnessCardiologyPhysical therapyMedicineMid regional pro adrenomedullinCardiology and Cardiovascular MedicinebusinessEuropean Heart Journal
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Inflammation, Endothelial Dysfunction and Arterial Stiffness as Therapeutic Targets in Cardiovascular Medicine

2016

In the last decades, many factors thought to be associated with the atherosclerotic process and cardiovascular events have been studied, and some of these have been shown to correlate with clinical outcome, such as arterial stiffness, endothelial dysfunction and immunoinflammatory markers. Arterial stiffness is an important surrogate marker that describes the capability of an artery to expand and contract in response to pressure changes. It can be assessed with different techniques, such as the evaluation of PWV and AIx. It is related to central systolic pressure and it is an independent predictor of cardiovascular morbidity and mortality in hypertensive patients, type 2 diabetes, end-stage…

medicine.medical_specialtyPathologyEndotheliumPopulation030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineInternal medicineDrug DiscoverymedicineAnimalsHumansPlatelet activationEndothelial dysfunctioneducationInflammationPharmacologyeducation.field_of_studySurrogate endpointbusiness.industryCardiovascular AgentsArteriesmedicine.diseasemedicine.anatomical_structureBlood pressureCardiovascular DiseasesCardiovascular agentArterial stiffnessCardiologyEndothelium Vascularbusiness030217 neurology & neurosurgeryCurrent Pharmaceutical Design
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2019

Muscle architecture is an important component of muscle function, and recent studies have shown changes in muscle architecture with fatigue. The stretch-shortening cycle is a natural way to study human locomotion, but little is known about how muscle architecture is affected by this type of exercise. This study investigated potential changes in medial gastrocnemius (MG) muscle architecture after exhaustive stretch-shortening cycle exercise. Male athletes (n = 10) performed maximal voluntary contractions (MVC) and maximal drop jump (DJ) tests before and after an exercise task consisting of 100 maximal DJs followed by successive rebound jumping to 70% of the initial maximal height. The exerci…

medicine.medical_specialtyPhysiologyChemistryMedial gastrocnemius030229 sport sciencesmedicine.disease_cause03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureJumpingPhysiology (medical)Internal medicineJoint stiffnessmedicineCardiologyFascicle lengthStretch reflexmedicine.symptomAnkleRange of motionMuscle architecture030217 neurology & neurosurgeryFrontiers in Physiology
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