Search results for "FORS"
showing 10 items of 285 documents
Folkehelsearbeid i norske kommuner : Hvilket folkehelseområde har høyest politisk prioritet i kommunene, og hvilke faktorer påvirker den politiske pr…
2020
Master's thesis in Public health science (ME516) In the process of planning the master project, we were several students who were interested in mapping the working and organizational conditions of the public health coordinators in the municipality. Therefore, we created the project: «Public health work in Norwegian municipalitiesr-2019» (FLINK-2019). The project has a quantitative approach in the form of a cross-sectional study, and the survey was sent to the public health coordinators in the municipalities. The purpose of this study is to map which area of public health has the highest political priority and which factors influence the political prioritization of this area. The study will …
Kommunal autonomi og statlig styring av folkehelsearbeidet : Hvilke kommunale og statlige faktorer anser folkehelsekoordinatorer som viktige for gjen…
2020
Master's thesis in Public health science (ME516) Background: In 2012, the Public Health Act was introduced, with one of the foremost objectives of equalizing social inequalities in health. For this work to be efficient, it must be systematic. The systematic public health work starts with a thorough preparation of municipal challenges in the so-called "overview document". Through previous parliamentary reports, it is recommended that a public health coordinator should lead such a municipal public health work and at the same time establish a cross-sectoral approach to public health work. However, research has shown that this work is insufficient, which is linked to the coordinators' working a…
Lokal iverksettelse av nasjonal folkehelsepolitikk : lokale beslutningstageres forståelse av styringssignalene i nasjonal folkehelsepolitikk
2016
Masteroppgave folkehelsevitenskap ME516 - Universitetet i Agder 2016 The purpose of this study is to investigate the local implementation of national public health policies. Attention focus on the early phase of the prosess of implementation, and exactly towards the local decisionmakers and how they understand the national public health policies. The study are based on a quality design were case-study are used as a strategy of research. The methods used are quality research interview. The Mayors and the Chief Municipal Executive from seven collaborative Municipalities are the strategic selection who were interviewed. The results end the conclusion of the study: The results in this study sho…
Bruk av begreper om praksis i NAV/ sosialtjenesten : Likhet og ulikhet i forståelser : Rapport fra HUSK – Agder / delprosjekt 2, våren 2010
2010
Sammendraget kommer til å inngå som en del av kolofonsiden og vil bli satt korrektinn på denne av bibliotektjenesten som i tillegg fyller ut feltene under.. (12 pt)Bakgrunnen for denne rapporten er arbeidet som har pågått i HUSK- Agder,delprosjekt 2; samarbeid sosialtjenesten - NAV, fra 2007-2009. Forfatterne, som beggeer vitenskapelig ansatte ved Universitetet i Agder, har hatt et særlig ansvar forarbeidsprosessen i dette prosjektet. Tittelen på rapporten; ”Bruk av begreper ompraksis i NAV/ sosialtjenesten”, peker mot en tematikk som ble aktualisert isamarbeidet mellom praktikere, brukere og forskere fra UiA i dette delprosjektet.Prosjektet som ble kalt ” Begrepsforståelse hos tjenesteyter…
Association of time under immunosuppression and different immunosuppressive medication on periodontal parameters and selected bacteria of patients af…
2017
Background Aim of this study was to investigate the association of the time under immunosuppression and different immunosuppressive medication on periodontal parameters and selected periodontal pathogenic bacteria of immunosuppressed patients after solid organ transplantation (SOT). Material and Methods 169 Patients after SOT (lung, liver or kidney) were included and divided into subgroups according their time under (0-1, 1-3, 3-6, 6-10 and >10 years) and form of immunosuppression (Tacrolimus, Cyclosporine, Mycophenolate, Glucocorticoids, Sirolimus and monotherapy vs. combination). Periodontal probing depth (PPD) and clinical attachment loss (CAL) were assessed. Periodontal disease severity…
The nicardipine-isoprenaline interaction in human and guinea-pig isolated airways
1994
Summary— The effects of the dihydropyridine calcium antagonist nicardipine on the concentration-response curves of relaxant compounds acting through the adenylate-cyclase/cAMP system (isoprenaline, forskolin, adenosine and theophylline) or by the cGMP pathway (sodium nitroprusside) were studied on human isolated bronchus and guinea-pig isolated trachea. These effects were compared with those of nifedipine (a dihydropyridine derivative) and theophylline (a non-selective phosphodiesterase inhibitor). Nicardipine, in the range of 0.01 to 1 μM, significantly potentiated the relaxant effects of isoprenaline, forskolin, adenosine and theophylline, whereas the effects of sodium nitroprusside were …
Mechanisms underlying hyperpolarization evoked by P2Y receptor activation in mouse distal colon
2006
In murine colonic circular muscle, ATP mediates fast component of the nerve-evoked inhibitory junction potentials, via activation of P2Y receptors and opening of apamin-sensitive Ca2+-dependent K+ channels. We investigated, using microelectrode recordings, the intracellular events following P2Y-receptor activation by electrical field stimulation or by adenosine 5'-O-2-thiodiphosphate (ADPbetaS), ATP stable analogue. The fast-inhibitory junction potential amplitude was reduced by thapsigargin or ciclopiazonic acid (CPA), sarcoplasmic reticulum Ca2+-ATPase inhibitors, by ryanodine, which inhibits Ca2+ release from ryanodine-sensitive stores, and by 9-(tetrahydro-2-furanyl)-9H-purin-6-amine (S…
Adrenergic modulation of the release of 5-hydroxytryptamine from the vascularly perfused ileum of the guinea-pig
1988
1. Isolated segments of the guinea-pig ileum were vascularly perfused and the release of 5-hydroxytryptamine (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) into the portal venous effluent was determined by h.p.l.c. with electrochemical detection. Test substances were applied via the arterial perfusion medium. 2. Isoprenaline (0.1 microM) increased the outflow of 5-HT and 5-HIAA maximally by about 75% and this was antagonized by propranolol (0.1 microM). Forskolin (1-10 microM) increased the outflow of 5-HT by approximately 105% and that of 5-HIAA by approximately 55%. The phosphodiesterase inhibitor AH 21-132 (0.1-1 microM) increased the outflow of 5-HT and 5-HIAA by about 70%. Isoprenaline…
Adrenoceptor- and cholinoceptor-mediated mechanisms in the regulation of 5-hydroxytryptamine release from isolated tracheae of newborn rabbits
1996
Abstract 1. Isolated tracheae of newborn rabbits were incubated in vitro and the outflow of 5-hydroxytryptamine (5-HT) was determined by h.p.l.c. with electrochemical detection. Evidence has previously been provided that this 5-HT outflow derives from neuroendocrine epithelial (NEE) cells of the airway mucosa. 2. Phenylephrine (1, 10 and 30 microM) enhanced the outflow of 5-HT by 80, 290 and 205%, respectively. 5-HT outflow evoked by 10 microM phenylephrine was not affected by the presence of the neurotoxin tetrodotoxin (1 microM). 3. Rauwolscine, ARC 239 (an alpha(2B)-adrenoceptor preferring antagonist), yohimbine and prazosin antagonized the effect of 10 microM phenylephrine in a concentr…
Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population
2010
BackgroundAlbeit several studies pointed out the pivotal role that CD4+T cells have in Multiple Sclerosis, the CD8+ T cells involvement in the pathology is still in its early phases of investigation. Proteasome degradation is the key step in the production of MHC class I-restricted epitopes and therefore its activity could be an important element in the activation and regulation of autoreactive CD8+ T cells in Multiple Sclerosis.Methodology/principal findingsImmunoproteasomes and PA28-alphabeta regulator are present in MS affected brain area and accumulated in plaques. They are expressed in cell types supposed to be involved in MS development such as neurons, endothelial cells, oligodendroc…