Search results for "FRAM"

showing 10 items of 2142 documents

Urinary neutrophil gelatinase-associated lipocalin and cystatin C compared to the estimated glomerular filtration rate to predict risk in patients wi…

2016

Abstract Introduction Impaired renal function, reflected by estimated glomerular filtration rate (eGFR) or cystatin C, is a strong risk predictor in the presence of acute myocardial infarction (AMI). Urinary neutrophil gelatinase-associated lipocalin (uNGAL) is an early marker of acute kidney injury. uNGAL might also be a good predictor of outcome in patients with cardiovascular disease. Aim of the present study was to evaluate the prognostic value of uNGAL compared to eGFR and cystatin C in patients with suspected AMI. Methods 1818 patients were enrolled with suspected AMI. Follow-up information on the combined endpoint of death or non-fatal myocardial infarction was obtained 6months after…

Malemedicine.medical_specialtyUrinary systemMyocardial InfarctionRenal function030204 cardiovascular system & hematologyurologic and male genital diseasesCohort Studies03 medical and health sciences0302 clinical medicineLipocalin-2Predictive Value of TestsRisk FactorsInternal medicinemedicineClinical endpointHumans030212 general & internal medicineMyocardial infarctionCystatin CAgedAged 80 and overFramingham Risk Scorebiologybusiness.industryAcute kidney injuryMiddle Agedmedicine.diseaseCystatin Cbiology.proteinCardiologyFemaleCystatinCardiology and Cardiovascular MedicinebusinessBiomarkersFollow-Up StudiesGlomerular Filtration RateInternational journal of cardiology
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Testosterone Levels in Males with Type 2 Diabetes and Their Relationship with Cardiovascular Risk Factors and Cardiovascular Disease

2010

ABSTRACT Introduction One of the factors involved in type 2 diabetes in males is a reduction in levels of testosterone, which has been shown to predict resistance to insulin and the development of cardiovascular diseases. Aim To assess the levels of testosterone in patients with type 2 diabetes and to evaluate their relationship with cardiovascular risk factors, peripheral arterial disease (PAD) and silent myocardial ischemia (SMI). Methods Total testosterone and sex hormone binding globulin were measured and free and bioavailable testosterones were calculated using Vermeulen's formula. Levels of total testosterone ≥12 nmol/L or free testosterone >225 pmol/L were considered normal. PAD was …

Malemedicine.medical_specialtyUrologyEndocrinology Diabetes and MetabolismMyocardial IschemiaArterial Occlusive DiseasesType 2 diabetesEndocrinologySex hormone-binding globulinInsulin resistanceRisk FactorsDiabetes mellitusInternal medicineHumansMedicineTestosteroneAgedFramingham Risk Scorebiologymedicine.diagnostic_testbusiness.industryTestosterone (patch)Middle Agedmedicine.diseasePsychiatry and Mental healthEndocrinologyDiabetes Mellitus Type 2Reproductive MedicineCardiovascular Diseasesbiology.proteinInsulin ResistanceMetabolic syndromebusinessLipid profileThe Journal of Sexual Medicine
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Tako-tsubo cardiomyopathy and microcirculation.

2010

Takotsubo cardiomyopathy was described for the first time in Japan in the 1990s. It is very similar to the ischemic cardiopathy both for clinical and instrumental characteristics. His peculiarity is an alteration of the ventricular contraction mechanism with hypo-akinesis of the apex and lateral segments of the left ventricle, associated with hyper-kinesis of the heart base which is responsible for the typical echocardiographic aspect of a cruet during the systole. However, the etiology of this cardiomyopathy is still unknown despite the fact that numerous hypothesis have been made. A single study of 16 patients proved multivasal damage by a BLASH SCORE analysis of the coronary radiography.…

Malemedicine.medical_specialtytako-tsubo cardiomyopathyCardiomyopathycoronary microcirculation; takotsubo; timi frame countHemodynamicsHealth InformaticsAnterior Descending Coronary ArteryCritical Care and Intensive Care MedicineCoronary AngiographyMicrocirculationTakotsubo CardiomyopathyInternal medicinemedicine.arteryCoronary CirculationMedicineHumansAgedbusiness.industryMicrocirculationmedicine.diseaseStenosisAnesthesiology and Pain Medicinemedicine.anatomical_structureRight coronary arteryCardiologyRadiographic Image Interpretation Computer-AssistedFemalebusinessTIMIBlood Flow VelocityArteryJournal of clinical monitoring and computing
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Prognostic Role of Late Gadolinium Enhancement in Patients With Hypertrophic Cardiomyopathy and Low-to-Intermediate Sudden Cardiac Death Risk Score

2019

Sudden cardiac death (SCD) is the most life-threating complication of hypertrophic cardiomyopathy. Guidelines of the European Society of Cardiology (ESC) suggest the implantation of an implantable cardioverter defibrillator in primary prevention according to a 5-year risk SCD score >= 6%. The aim of the study is to evaluate the prognostic role of late gadolinium enhancement (LGE) in patients with a 5-year risk SCD score <6%. In this multicenter study, we performed cardiac magnetic resonance in 354 consecutive hypertrophic cardiomy-opathy patients (257 males, range of age 54 +/- 17) with a risk SCD score <6% (302 with <4% and 52 with >= 4 and <6% risk). Hard cardiac events,…

Malemedicine.medical_treatmentLeftCardiomyopathyContrast MediaGadolinium030204 cardiovascular system & hematologyVentricular Function Left030218 nuclear medicine & medical imagingSudden cardiac death0302 clinical medicineRisk Factorshemic and lymphatic diseasesVentricular FunctionFramingham Risk Scoremedicine.diagnostic_testIncidenceHypertrophic cardiomyopathyMiddle AgedImplantable cardioverter-defibrillatorPrognosisMagnetic Resonance ImagingHypertrophic Cardiomyopathy Sudden Cardiac Death.DeathSurvival RateItalyCineCardiologyFemaleCardiology and Cardiovascular MedicineCardiaccongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyCardiomyopathyHeart VentriclesMagnetic Resonance Imaging CineRisk Assessment03 medical and health sciencesInternal medicinemedicineHumanscardiovascular diseasesRetrospective Studiesbusiness.industryMyocardiumMagnetic resonance imagingRetrospective cohort studyCardiomyopathy HypertrophicCardiomyopathy Hypertrophic; Contrast Media; Death Sudden Cardiac; Female; Follow-Up Studies; Gadolinium; Heart Ventricles; Humans; Incidence; Italy; Magnetic Resonance Imaging Cine; Male; Middle Aged; Myocardium; Prognosis; ROC Curve; Retrospective Studies; Risk Assessment; Risk Factors; Survival Rate; Ventricular Function Leftmedicine.diseaseSuddenSudden cardiac deathDeath Sudden CardiacROC CurveHypertrophicComplicationbusinessFollow-Up Studies
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Rubinstein–Taybi syndrome 2 with cerebellar abnormality and neural tube defect

2019

Rubinstein-Taybi syndrome (RSTS) is a rare dominant disorder with intellectual disability, postnatal growth deficiency, and multiple congenital anomalies. Approximately 50-70% of the patients have a mutation in the CREBBP gene (RSTS1) and 5-10% display an EP300 gene mutation (RSTS2). Craniospinal abnormalities such as microcranium, scoliosis, and lordosis are frequent findings in RSTS1, but malformations of the brain or spinal cord are seen only occasionally. Here, we report on a 3-year-old boy with facial abnormalities of RSTS, broad thumbs and halluces, developmental delay, autistic features, cerebellar underdevelopment, and a neural tube defect. Molecular diagnostic of the CREBBP and EP3…

Malespeech delayHeterozygoteCerebellumGenotypecerebellar abnormalityScoliosisGene mutationPathology and Forensic MedicineCerebellummedicinetethered cordHumansmicrocephalyGenetic TestingNeural Tube DefectsFrameshift MutationEP300Genetic Association StudiesGenetics (clinical)Sequence DeletionRubinstein-Taybi Syndromeautistic behaviorRubinstein–Taybi syndromeNeural tube defectGenome Humanbusiness.industryNeural tubeHigh-Throughput Nucleotide Sequencingstereotypic movementsvesicoureteral refluxOriginal Articleslumbosacral myeloceleExonsGeneral MedicineAnatomymedicine.diseaseSpinal cordCREB-Binding Proteinmedicine.anatomical_structuresyringohydromyeliaChild PreschoolMutationPediatrics Perinatology and Child Healthbroad thumbs and hallucesAnatomybusinessE1A-Associated p300 ProteinClinical Dysmorphology
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Relativistic corrections and unitary equivalence in elastic electron deuteron scattering.

1993

The role of unitary equivalence of relativistic corrections in elastic electron deutron scattering is studied, starting from a class of approximately, unitarily equivalent Hamiltonians and using consistent charge density operators. The connection of various formal approaches for deriving the relativistic corrections to wave functions and operators are discussed in detail. For reasons of simplicity, we have chosen a pure one-pion-exchange model and calculated the charge and quadrupole form factors of the deuteron. The numerical results show that the unitary equivalence holds at small momentum transfers, but breaks down rather soon with increasing momentum transfers (\ensuremath{\lesssim}5 ${…

Many-body problemElastic scatteringMomentumPhysicsNuclear and High Energy PhysicsScatteringQuantum mechanicsCharge (physics)Connection (algebraic framework)Few-body systemsWave functionPhysical review. C, Nuclear physics
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Collective Behavior of Price Changes of ERC-20 Tokens

2020

We analyze a network constructed from tokens developed on Ethereum platform. We collect a large data set of ERC-20 token prices; the total market capitalization of the token set is 50.2 billion (109) US dollars. The token set includes 541 tokens; each one of them has a market capitalization of 1 million US dollars or more. We construct and analyze the networks based on cross-correlation of tokens’ returns. We find that the degree distributions of the resulting graphs do not follow the power law degree distribution. We cannot find any hierarchical structures nor groupings of ERC-20 tokens in our analysis. peerReviewed

Market capitalizationCryptocurrencymarkkina-arvoDegree (graph theory)Computer sciencevoitot (talous)fegree distributionConstruct (python library)Security tokenDegree distributioncryptocurrencykorrelaatioSet (abstract data type)virtuaalivaluuttacross correlation matrixtokenEconometricsData set (IBM mainframe)
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Virtual and augmented reality: Advancing research in consumer marketing

2020

Abstract Virtual reality (VR) and augmented reality (AR) technologies are having a profound impact on a variety of marketing practices and are attracting increasing attention from marketing researchers. In this article, we review developments in VR/AR applications and research in the area of consumer marketing. We propose a conceptual framework for VR/AR research in consumer marketing that centers around consumer experiences provided by VR/AR applications along the customer journey and the effectiveness of such applications, and delve into the key concepts and components of the framework. Next, we provide a comprehensive overview of VR/AR applications in current practices and extant researc…

MarketingComputer science05 social sciencesVirtual realityVariety (cybernetics)Consumer experienceExtant taxonConceptual frameworkVirtual reality Augmented reality Consumer experience Customer journey VR/AR effectiveness0502 economics and businessKey (cryptography)050211 marketingAugmented realityMarketing050203 business & management
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The influence of personal and social identity on the clothing consumption of adolescents

2016

We consider the influence of personal and social identity among adolescents on the importance they attach to clothing products and brands. The conceptual framework includes more conventional variables such as socialization (family, peers, media, and celebrities) and individual characteristics (gender and grade level). Based on a sample of 1,596 French high school adolescents, our results highlight: (i) the influence of identity on the importance attached to product and brand; (ii) the mediating effects of personal and social identities; and (iii) the moderating effects of gender and grade level. We conclude with an analysis of theoretical contributions, practical implications, and future re…

MarketingConsumption (economics)Public Administrationbusiness.industry05 social sciencesSocializationIdentity (social science)Sample (statistics)ClothingManagement of Technology and Innovation0502 economics and business050211 marketingThe Conceptual FrameworkProduct (category theory)Business and International ManagementSocial identity theorybusinessPsychologySocial psychology050203 business & managementCanadian Journal of Administrative Sciences / Revue Canadienne des Sciences de l'Administration
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Effectuation and foreign market entry of entrepreneurial firms

2015

Purpose – The purpose of this study is to examine the decision-making process for entrepreneurial firms when entering foreign markets and how and why they entered those markets. Design/methodology/approach – A nascent theory in entrepreneurship called effectuation is combined with internationalization process theory as the conceptual framework to study decision-making under uncertainty. The central concept in both these theories is relationships and how they can be used to gain knowledge and thus reduce uncertainty and in the case of effectuation to co-create opportunities to enter foreign markets. The research design involves a multiple case study of software firms from Finland and New Ze…

MarketingEffectuationEntrepreneurshipmedia_common.quotation_subjectContext (language use)yrittäjyyscausationInternationalizationOriginalitynetworksProcess theoryThe Conceptual FrameworkBusinessCausationMarketingeffectuationinternationalizationforeign market entrymedia_commonEuropean Journal of Marketing
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