Search results for "FUNGAL"
showing 10 items of 1116 documents
Performance of existing definitions and tests for the diagnosis of invasive fungal diseases other than invasive candidiasis and invasive aspergillosi…
2021
Diagnòstic; Malalties fúngiques invasores; Pneumocystis Diagnóstico; Enfermedades fúngicas invasivas; Pneumocystis Diagnosis; Invasive fungal diseases; Pneumocystis The Fungal Infections Definitions in Intensive Care Unit (ICU) patients (FUNDICU) project aims to provide standard sets of definitions for invasive fungal diseases (IFDs) in critically ill, adult patients, including invasive aspergillosis (IA), invasive candidiasis (IC), Pneumocystis jirovecii pneumonia (PJP), and other non-IA, non-IC IFDs. The first step of the project was the conduction of separated systematic reviews of the characteristics and applicability to critically ill, adult patients outside classical populations at ri…
Molecular methods for the diagnosis and characterization of phytopathogenic fungi of quarantine concern or causing emerging plant diseases
2021
In the context of molecular techniques applied to Plant Pathology, this Ph.D. thesis has pursued the following major objectives: i) to develop new diagnostic protocols for fungal pathogens; ii) to study the metabolic and physiological effects determined by new and emerging fungal pathogens; iii) to contribute to develop management strategies of diseases caused by quarantine and/or emerging fungi on plant species typical of the Mediterranean region. To fulfill these objectives, the following specific studies have been developed: • “Fusarium circinatum an emergent and quarantine pathogen of pine worldwide: its detection and its interaction with Phytophthora species (P. cambivora and P. parvis…
Fungal root colonization and arbuscular mycorrhizal fungi diversity in soils of grasslands with different mowing intensities
2022
management that has changed in recent decades. The intensity of human-induced disturbances (primarily removal of plant biomass by various methods) has decreased, leading to changes in plant species composition and declines in plant diversity in these communities. So far, no studies have shown how mowing affects fungal communities in both roots and soils and their relation with plant community parameters and soil chemical properties in different grassland types. We thus compared the impact of mowing intensity (low, moderate, high) on root colonization by common root-inhabiting fungi, namely arbuscular mycorrhizal fungi (AMF), dark septate endophytes (DSE), and Olpidium spp., as well as on AM…
The effect of grazing history on fungal diversity in broadleaved wood pastures
2012
Traditional rural biotopes such as wood pastures are species rich habitats which have been created by extensive agriculture. In all European countries both the quality and quantity of traditional rural biotopes have drastically decreased during the past century because of increasing farming intensity. This decline is causing a threat to many species, but very little is known about the conservation ecology of fungi living in wood pastures. Considering vascular plants, it is known that sites with long management history have higher species richness compared to abandoned sites. It is also known that species richness is highest with intermediate grazing intensity. In this study I investigated i…
Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infect…
2017
Invasive pulmonary aspergillosis (IPA) is a life-threatening lung disease of hematological malignancy or bone marrow transplant patients caused by the ubiquitous environmental fungus Aspergillus fumigatus. Current diagnostic tests for the disease lack sensitivity as well as specificity, and culture of the fungus from invasive lung biopsy, considered the gold standard for IPA detection, is slow and often not possible in critically ill patients. In a previous study, we reported the development of a novel non-invasive procedure for IPA diagnosis based on antibody-guided positron emission tomography and magnetic resonance imaging (immunoPET/MRI) using a [64Cu] DOTA-labeled mouse monoclonal anti…
Durum wheat root and foot rot complex in Sicily
2009
Monitoring fungal biodiversity – towards an integrated approach
2012
Biodiversity information databases and platforms have seen considerable progress in recent years. They have a high potential in conservation science in general, but may be even more revolutionary in relation to poorly known species groups such as fungi, whose practical conservation work has been jeopardised by scattered and poorly controlled information. We review the tradition of collecting information on species occurrences in mycology and discuss the characteristics of the present fungal biodiversity information databases. With a special focus on population trend monitoring of fruit body producing macrofungi, we emphasise several unrealised opportunities of these databases and point out …
Differential Translational Efficiency of the mRNAs Isolated from Derepressed and Glucose Repressed Saccharomyces cerevisiae
1987
Summary: Carbon catabolite derepression induced changes in the pool of yeast mRNAs translatable in a protein-synthesizing reticulocyte system. Competition experiments with globin mRNA showed that the mRNA population obtained from derepressed cells possessed a higher translational efficiency than mRNA from repressed cells. The mRNAs that could account for the high translational efficiency of the derepressed mRNA were not detected in cells growing in glucose-rich medium. Analysis of protein synthesis in the presence of 7-methylguanosine 5′-phosphate indicated that the initiation factors recognizing the 5′-terminal structure of capped messengers interacted with lower affinity with the represse…
Identification of a Functional Homolog of the Yeast Copper Homeostasis Gene ATX1 from Arabidopsis1
1998
Abstract A cDNA clone encoding a homolog of the yeast (Saccharomyces cerevisiae) gene Anti-oxidant 1(ATX1) has been identified from Arabidopsis. This gene, referred to as CopperCHaperone(CCH), encodes a protein that is 36% identical to the amino acid sequence of ATX1 and has a 48-amino acid extension at the C-terminal end, which is absent from ATX1 homologs identified in animals. ATX1-deficient yeast (atx1) displayed a loss of high-affinity iron uptake. Expression of CCH in the atx1 strain restored high-affinity iron uptake, demonstrating thatCCH is a functional homolog of ATX1. When overexpressed in yeast lacking the superoxide dismutase geneSOD1, both ATX1 and CCHprotected the cell from t…