Search results for "Faces"
showing 10 items of 3167 documents
Structural Features of β-Cyclodextrin Solvation in the Deep Eutectic Solvent, Reline
2020
The inherently amphiphilic nature of native cyclodextrins (CDs) determines their peculiar molecular encapsulation features, enabling applications such as targeted drug nanodelivery, aroma protection, etc. On the contrary, it may also lead to poor solubility in water and other organic solvents and to potentially detrimental flocking in these media, thus posing limitations to more extensive usage. Here we use small angle X-ray scattering to show that deep eutectic solvent reline (1:2 choline chloride:urea) succeeds in dissolving large amounts of beta-CD (at least 800 mg/mL, compared with the solubility in water of 18 mg/mL), without aggregation phenomena occurring. At the microscopic level, m…
Environmental control on granular clinoforms of ancient carbonate shelves
2006
The purpose of this paper is to document the influence of depositional environments on shallow-water, low-relief clinoforms from the description of five ancient carbonate platforms: the Neoproterozoic (Namibia), Middle Jurassic (France), Lower Cretaceous (France), Upper Cretaceous (Oman) and Miocene (Turkey). These examples have been investigated on the basis of field observations. The clinoforms are described with reference to geometric and compositional attributes: declivity, shape, height, sedimentary structures, sediment fabric and components. The results show great variability in stratal geometry, declivity and facies distribution: (1) depositional profiles vary from exponential, to si…
Reconfigurable nonlinear response of dielectric and semiconductor metasurfaces
2021
Abstract Optically resonant dielectric and semiconductor metasurfaces are an emerging and promising area of nanophotonics and light–matter interaction at the nanoscale. Recently, active tuning of the linear response and nonlinear effects of these components has received an increasing amount of interest. However, so far these research directions have remained separated with only few sporadic works that study their combination beginning to appear in the literature. The evolution of nonlinear metasurfaces based on dielectric and semiconductor materials toward reconfigurable and dynamic components could potentially answer the demand of integrated on-chip components that realize essential functi…
Antibody recognition of fluorinated MUC1 glycopeptide antigens.
2011
The syntheses of various fluorinated MUC1 glycopeptide antigens and their specific binding to serum antibodies from mice immunized with natural and fluorinated TF(6)-MUC1-TTox conjugate vaccines are presented.
Synthesis of a MUC1-glycopeptide-BSA conjugate vaccine bearing the 3'-deoxy-3'-fluoro-Thomsen-Friedenreich antigen.
2011
A novel MUC1-glycopeptide–BSA conjugate vaccine with a specifically fluorinated Thomsen–Friedenreich antigen side chain at Thr6 was prepared. Preliminary immunological experiments reveal specific binding of the tumor-associated glycopeptide antigen analog by anti-MUC1-mouse antibodies.
Structure−Dynamics Coupling between Protein and External Matrix in Sucrose-Coated and in Trehalose-Coated MbCO: An FTIR Study
2004
We performed FTIR measurements on carboxy-myoglobin (MbCO) embedded in a sucrose−water matrix to study the degrees of freedom coupling between protein and external matrix in such a system. The work was undertaken on the light of recent results by Giuffrida et al. (J. Phys. Chem. B 2003, 107, 13211−13217), who evidenced, in trehalose-coated MbCO, a structured water−sugar environment of the protein, tightly coupled to the heme pocket structure. Such information was obtained through a suitable analysis of the temperature dependence of the CO stretching and of the water association bands in samples of different content of residual water. We applied here the same analysis to sucrose-coated MbCO.…
Tailoring oxide properties: An impact on adsorption characteristics of molecules and metals
2014
Abstract Both density functional theory calculations and numerous experimental studies demonstrate a variety of unique features in metal supported oxide films and transition metal doped simple oxides, which are markedly different from their unmodified counterparts. This review highlights, from the computational perspective, recent literature on the properties of the above mentioned surfaces and how they adsorb and activate different species, support metal aggregates, and even catalyse reactions. The adsorption of Au atoms and clusters on metal-supported MgO films are reviewed together with the cluster׳s theoretically predicted ability to activate and dissociate O 2 at the Au–MgO(100)/Ag(100…
Dual Information Systems: Supporting Organizational Working and Learning by Making Organizational Memory Transparent
1999
The conceptual design of most computer-based information systems reflects a dualism of technology. During the development phase, part of the work-domain-related knowledge is formalized and encoded in the software, making it difficult for users to reflect on and use this knowledge. This design--use dualism contributes to the deterioration of the interpretive flexibility of information systems. In this article, we outline an information systems architecture called Dual Information Systems (DIS) that incorporates the concepts of an organizational memory information system (OMIS) in a broader framework. DIS help bridge the design--use dualism by providing organizations with a set of services th…
Redesigning Computer-Supported Work Processes with Dual Information Systems: The Work Process Benchmarking Service
1999
The conceptual design of most computer-based information systems reflects a dualism of technology. During the development phase, part of the work-domain-related knowledge is formalized and encoded in the software, making it difficult for users to reflect on and use this knowledge. This design/use dualism contributes to the deterioration of the interpretive flexibility of information systems. We propose an information systems architecture called Dual Information Systems (DIS) that helps bridge the design/use dualism by providing organizations with a set of services that enable and reinforce both effective, institutionalized working and the questioning and (re)construction of computer-support…
Harnessing Fluorescence versus Phosphorescence Branching Ratio in (Phenyl)n-Bridged (n = 0–5) Bimetallic Au(I) Complexes
2013
We have designed and synthesized a series of Au(I) complexes bearing either an alkynyl–(phenylene)n–diphosphine (A-0–A-3) or a (phenylene)n–diphosphine (B-1–B-5) bridge, among which the effective distance between Au(I) and the center of the emitting ππ* chromophore can be fine-tuned via the insertion of various numbers of phenylene spacers. We then demonstrated for the first time in a systematic manner the decrease of rate constant for S1 → T1 intersystem crossing (ISC) kisc as the increase of the effective distance. The results also unambiguously showed that the phosphorescence could be harvested via higher S0 → Sn (n > 1) electronic excitation, followed by fast Sn → Tm ISC and then the po…