Search results for "Fall"

showing 10 items of 964 documents

Nueva Propuesta Museográfica del Museo Fallero de Valencia

2011

El objetivo de dicho Trabajo Fin de Máster es remarcar las deficiencias de la actual propuesta museográfica del Museo. Las Fallas contribuye al desarrollo de la ciudad y de todos los agentes que realizan la mejora y el crecimiento de la propia realidad de la urbe. Hay que tener en cuenta las capacidades, recursos y posiciones alcanzadas que limitan las posibilidades de aprovechar las oportunidades, por lo que hay que intentar evitarlas o paliarlas. En el caso de las Fallas las posibles debilidades son la falta de una protección adecuada para el Museo Fallero, institución que conserva el Arte Efímero y que debería tener el estatus de Museo para poder recibir una serie de subvenciones para su…

MuseografíaFallasFestividadesPatrimonio CulturalPatrimonio InmaterialUNESCO::HISTORIA::Historia por especialidades::Historia del arteMuseo
researchProduct

Rockfall hazard assessment of the Monte Gallo Oriented Nature Reserve area (Southern Italy)

2021

Abstract The Monte Gallo area is a carbonate relief that develops a significant nature reserve and highly attracts tourism to the urbanized area of the City of Palermo (Southern Italy). The slopes are affected by several rockfall events, which have also caused death, injuries, material damage, and a strong social and economic impact. Here, a detailed geological and geotechnical study to assess the rockfall hazard relating to two sectors of the mount has been carried out. The hazard assessment at the slope scale was performed based on geological, geomorphological, geomechanical, and seismic analysis. Using both analytical and empirical methods and by means of different software, the reconstr…

Nature reserveSicily Empirical MethodgeographyRockfallgeography.geographical_feature_categorySeismic surveyGeomechanical analysisRockfall hazardPhysical geographyHazard analysisNumerical MethodGeologyIOP Conference Series: Earth and Environmental Science
researchProduct

Minimally invasive interval debulking surgery in ovarian neoplasm (MISSION trial–NCT02324595): a feasibility study

2016

Background Laparoscopy has acquired an increasing role in the management of ovarian cancer. Laparoscopic cytoreduction could represent a new frontier for selected patients after neoadjuvant chemotherapy (NACT). Objective We sought to assess feasibility and early complication rate of minimally invasive (MI) interval debulking surgery (IDS) in stage III-IV epithelial ovarian cancer (EOC) patients after NACT. Study Design This is a phase II multicentric study in advanced EOC cases with clinical complete response after NACT, according to Gynecologic Cancer Intergroup and Response Evaluation Criteria In Solid Tumors criteria. Institutional review board approval was obtained and all patients sign…

Neoplasm Residualmedicine.medical_treatmentchemotherapyresidual0302 clinical medicine80 and overMedicineminimally invasive surgeryAged 80 and overOvarian Neoplasms030219 obstetrics & reproductive medicineadvanced ovarian cancerMedicine (all)Obstetrics and GynecologyCytoreduction Surgical ProceduresBowel resectionMiddle AgedDebulkinglaparoscopic cytoreductionNeoadjuvant TherapyIntestinesChemotherapy AdjuvantResponse Evaluation Criteria in Solid Tumors030220 oncology & carcinogenesisinterval debulking surgeryFemaleMedian bodyPeritoneumOmentumneoadjuvant chemotherapyAdultmedicine.medical_specialtyOvariectomyadvanced ovarian cancer; interval debulking surgery; laparoscopic cytoreduction; minimally invasive surgery; neoadjuvant chemotherapy; quality of life; Adult; Aged; Aged 80 and over; Appendectomy; Chemotherapy Adjuvant; Fallopian Tubes; Feasibility Studies; Female; Humans; Hysterectomy; Intestines; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence Local; Neoplasm Residual; Omentum; Ovarian Neoplasms; Ovariectomy; Peritoneum; Cytoreduction Surgical Procedures; Laparoscopy; Medicine (all); Obstetrics and GynecologyHysterectomy03 medical and health sciencesadjuvantlocalAppendectomyHumansSurvival rateFallopian TubesAgedHysterectomybusiness.industryAdvanced ovarian cancer interval debulking surgery laparoscopic cytoreduction minimally invasive surgery neoadjuvant chemotherapy quality of life adult aged 80 and over appendectomy chemotherapy adjuvant fallopian tubes feasibility studies female humans hysterectomy intestines middle aged neoadjuvant therapy neoplasm recurrence local neoplasm residual omentum ovarian neoplasms ovariectomy peritoneum cytoreduction surgical procedures laparoscopyPerioperativeneoplasm recurrenceSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAquality of lifeFeasibility StudiesLaparoscopyLymphadenectomyNeoplasm Recurrence LocalbusinessneoplasmAmerican Journal of Obstetrics and Gynecology
researchProduct

Fenotipo celular de las neuronas sensitivas afectadas en la ataxia de Friedreich

2016

Tesis Doctoral, 223 páginas, 64 figuras, 13 tablas.

Neurona sensitiva ganglio dorsalfallo mitocondrialfrataxinaataxia de Friedreichneurona sensitiva ganglio dorsalFallo mitocondrialReceptores acoplados a proteínas Greceptores acoplados a proteínas GDishomeostasis del calcioFrataxinaNeurodegeneración dying backneurodegeneración dying back240000dishomeostasis del calcioAtaxia de FriedreichModelo murino YG8Rmodelo murino YG8R320000
researchProduct

Pharmacogenetics of treatments for pancreatic cancer

2019

Introduction: Despite clinical efforts, pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. The scarcity of effective therapies can be reflected by the lack of reliable biomarkers to adapt anticancer drugs prescription to tumors’ and patients’ features. Areas covered: Pharmacogenetics should provide the way to select patients who may benefit from a specific therapy that best matches individual and tumor genetic profile, but it has not yet led to gains in outcome. This review describes PDAC pharmacogenetics findings, critically reappraising studies on polymorphisms and -omics profiles correlated to response to gemcitabine, FOLFIRINOX, and nab-paclitaxel combinations, as well as l…

Oncologymedicine.medical_specialtyPancreatic ductal adenocarcinomaendocrine system diseasesFOLFIRINOXToxicology030226 pharmacology & pharmacyvalidated tests and clinical trial03 medical and health sciencesnab-paclitaxel0302 clinical medicinePancreatic cancerInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineBiomarkers TumorAnimalsHumansneoplasmspharmacogenetic studieNab-paclitaxelPharmacologyAntineoplastic Combined Chemotherapy Protocolbusiness.industryAnimalPatient SelectionPharmacogeneticfungigemcitabinePancreatic Neoplasmfood and beveragesGeneral MedicinePancreatic cancermedicine.diseasePrognosisSettore CHIM/08 - Chimica Farmaceuticadigestive system diseasesGemcitabinePancreatic NeoplasmsFOLFIRINOXPharmacogenetics030220 oncology & carcinogenesispromises and pitfalls of pharmacogenetic approachebusinessPharmacogeneticsmedicine.drugCarcinoma Pancreatic DuctalHumanExpert Opinion on Drug Metabolism and Toxicology
researchProduct

Selection of the Optimal Design Rainfall Return Period of Urban Drainage Systems

2014

Abstract The aim of this work is to define a methodology to identify the optimal rainfall return period for the design of urban drainage systems. The choice of the optimal return period is made minimizing the total costs of the system: the sewer network is dimensioned for a set of possible design rainfall return periods, and the corresponding construction, maintenance and operation costs are evaluated. For each scenario, the total expected damage from flooding caused by rainfall events with return period greater than the design one is then estimated by hydraulic simulation. This methodology has been applied to a small urban catchment in Palermo (Italy).

Optimal designHydrologyReturn periodgeographyexpected damagesgeography.geographical_feature_categorydesign rainfallTotal costDrainage systemexpected damages.Flooding (psychology)Environmental engineeringDrainage basinGeneral Medicinereturn periodconstruction costsfloodingWork (electrical)construction costDrainage system (geomorphology)Environmental scienceDrainageEngineering(all)Procedia Engineering
researchProduct

Hedging foreign exchange rate risk: Multi-currency diversification

2016

Abstract This article proposes a multi-currency cross-hedging strategy that minimizes the exchange risk. The use of derivatives in small and medium-sized enterprises (SMEs) is not common but, despite its complexity, can be interesting for those with international activities. In particular, the reduction in the exchange risk borne through the use of natural multi-currency cross-hedging is measured, considering Conditional Value-at-Risk (CVaR) and Value-at-Risk (VaR) for measuring market risk instead of the variance. CVaR is minimized using linear programmes, while a multiobjective genetic algorithm is designed for minimizing VaR, considering two scenarios for each currency. The results obtai…

Organizational Behavior and Human Resource ManagementEconomicsFinancial economicsStrategy and Management0211 other engineering and technologiesDiversification (finance)02 engineering and technologyConditional Value-at-Riskddc:6500502 economics and businessEconometricsEconomicsBusinessG32G11Business and International ManagementHedge (finance)Rate riskMarketing021110 strategic defence & security studiesCVAR05 social sciencesValue-at-RiskBusiness FinanceManagementExpected shortfallC63Market riskCurrencyTourism Leisure and Hospitality ManagementMulti-currency diversificationMultiobjective genetic algorithm050211 marketingFinanceValue at riskCross-hedgingEuropean Journal of Management and Business Economics
researchProduct

Standing Together or Falling Apart? Understanding Employees’ Responses to Organizational Identity Threats

2020

How do employees respond to organizational identity threats? Despite its theoretical and practical importance, this question has had surprisingly little research devoted to it. In particular, evide...

Organizational identityStrategy and Management05 social sciencesIdentity (social science)050109 social psychologyGeneral Business Management and AccountingFalling (accident)Management of Technology and Innovation0502 economics and businessmedicine0501 psychology and cognitive sciencesSociologyIdentification (psychology)medicine.symptomAttributionSocial psychology050203 business & managementAcademy of Management Review
researchProduct

Interstitial pregnancy in a patient with ipsilateral adnexal absence: Case report and literature review

2013

Unilateral ovarian absence (UOA) with fallopian tube absence is a rare condition. The true incidence is unknown. Here, we report a case of a woman with left tubal and ovarian absence, undergoing laparoscopy for an ipsilateral interstitial pregnancy (IP). The gestational mass was excided using the purse string technique to achieve better haemostasis. Probable etiologies are discussed and literature reviewed. According to our analysis the reproductive outcome of women affected by this rare anomaly is not compromised. Its impairment should be related to comorbidities or other unexplained causes. © Copyright 2014, CIC Edizioni Internazionali, Roma.

Ovarian agenesiAdnexal agenesiObstetrics and GynecologyPurse string techniqueUro-genital malformationFallopian tube absenceUnilateral ovarian absenceInterstitial pregnancy
researchProduct

Unpredicted ovulations and conceptions during early pregnancy: an explanatory mechanism of human superfetation

2012

In this bioessay, a literature review on human superfetation was performed in order to find epidemiological variables associated with this phenomenon. Thereafter, an explanatory mechanism of superfetation compatible with the endocrinological, histological and physiological changes undergone by women during early pregnancy is proposed. Superfetation can be defined as the ovulation, fertilisation and implantation of a second or additional embryo(s) during pregnancy. The literature review evidences a small discordance in gestational age between dizygotic twins in humans (range: 2–4 weeks; mean ± s.e.m.: 3.3 ± 0.3 weeks). This difference is compatible with a luteal out-of-phase (LOOP; i.e. atyp…

Ovulationmedia_common.quotation_subjectTwinsPhysiologyGestational AgeSuperfetationReproductive technologyLuteal PhaseLuteal phaseBiologyEndocrinologyOvarian FolliclePregnancyDeciduaTwins DizygoticGeneticsmedicineHumansEmbryo ImplantationSuperfetationMolecular BiologyOvulationmedia_commonPregnancyEstradiolGestational ageAnatomymedicine.diseaseDecidual reactionmedicine.anatomical_structureReproductive MedicineFertilizationFemaleAnimal Science and ZoologyPregnancy MultipleDevelopmental BiologyBiotechnologyFallopian tubeReproduction, Fertility and Development
researchProduct