Search results for "Family aggregation"

showing 3 items of 13 documents

The risk of minor depression in families of probands with major depression: sex differences and familiality.

1992

Currently it is not clear whether minor forms of unipolar depression not matching the criteria of “major depression” should be considered as a separate diagnostic category. A controlled family study examined the familial aggregation of minor depression among probands with unipolar major depression. In the families of these probands the relative risk for minor depression was elevated by a similar magnitude to the risk for major depression. Threrefore, the diagnostic category “minor depression” would not increase diagnostic sensitivity at the expense of diagnostic specificity as far as familiality is the criterion. In agreement with recent epidemiological studies, minor depression did not rev…

ProbandAdultMalemedicine.medical_specialtyMinor (academic)Sex FactorsRisk FactorsEpidemiologymedicinePrevalenceHumansPharmacology (medical)Risk factorPsychiatryBiological PsychiatryDepression (differential diagnoses)Family HealthPsychiatric Status Rating ScalesDepressive DisorderFamily aggregationGeneral MedicinePsychiatry and Mental healthPsychotic DisordersRelative riskSchizophreniaFemalePsychologySex ratioEuropean archives of psychiatry and clinical neuroscience
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The impact of the endogenous subtype on the familial aggregation of unipolar depression.

1991

The endogenous/non-endogenous distinction of unipolar major depression is widely accepted, as is the family study approach to the validation of diagnostic distinctions. Rates of affective disorders were examined in 689 first-degree relatives of 184 patients with unipolar major depression and were compared with 312 first-degree relatives of 80 healthy controls. Only unipolar depression and alcoholism were more common in families of depressed probands compared with families of healthy controls. As a variety of diagnostic definitions of endogenous depression have been proposed, probands and relatives were diagnosed in a polydiagnostic manner. None of the five diagnostic definitions of endogeno…

ProbandMalemedicine.medical_specialtyEndogenybehavioral disciplines and activitiesDelusionsArousalDiagnosis DifferentialChild of Impaired ParentsRisk Factorsmental disordersmedicineHumansPharmacology (medical)PsychiatryBiological PsychiatryDepression (differential diagnoses)Depressive DisorderGeneral NeuroscienceMental DisordersFamily aggregationGeneral MedicineFamilial riskMiddle AgedCircadian RhythmPsychiatry and Mental healthNeuropsychology and Physiological PsychologyPhenotypeEndogenous depressionFemalePsychologyArousalClinical psychologyEuropean archives of psychiatry and clinical neuroscience
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Prevalence of essential tremor: A door-to-door survey in Terrasini, Sicily

1994

As part of a door-to-door neuroepidemiologic survey, we investigated the frequency and distribution of essential tremor (ET) in a Sicilian municipality. During phase 1, we administered a screening instrument for tremor to 7,653 persons residing in Terrasini (Palermo province). During phase 2, neurologists evaluated those subjects who had screened positive. The diagnoses, based on specified clinical criteria, were reviewed to increase reliability across neurologists. We found 31 subjects affected by ET (17 men, 14 women); 11 patients (35.5%) reported a familial aggregation. The prevalence of ET as of November 1, 1987, was 405.1 per 100,000 for the total population, and 1,074.9 per 100,000 fo…

medicine.medical_specialtyEssential tremorbusiness.industryFamily aggregationGeographic variationNeurological disorderTotal populationmedicine.diseaseSex factorsEpidemiologymedicineNeurology (clinical)businessScreening instrumentDemographyNeurology
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