Search results for "Farm"

showing 10 items of 3554 documents

Chemical composition of the essential oil of the local endemics Centaurea davidovii and C. parilica (Asteraceae, sect. Lepteranthus) from Bulgaria

2014

In the present study the chemical compositions of the essential oils from aerial parts of Centaurea davidovii Urum. and C. parilica Stoj. & Stef., both endemic to Bulgaria, were evaluated by GC and GC-MS. The main components of C. davidovii were β-eudesmol (13.9%), spathulenol (13.3%), caryophyllene oxide (10.1%) and ( Z)-phytol (5.4%). The main components of C parilica were hexadecanoic acid (39.2%), ( Z, Z)-9,12-octadecadienoic acid (11.9%), caryophyllene oxide (6.8%) and spathulenol (6.6%). In order to compare the essential oils composition of these taxa and of related species a PCA analysis was carried out.

CentaureaC. davidoviiPlant Scienceβ-eudesmolessential oilSpathulenollaw.inventionlawDrug DiscoveryBotanyhexadecanoic acidspathulenolOils VolatileCentaurea specieSettore BIO/15 - Biologia FarmaceuticaC. parilicaBulgariaEndemismChemical compositionessential oilsEssential oilPharmacologybiologyPlant ExtractsGeneral MedicineSettore CHIM/06 - Chimica OrganicaCentaurea davidoviiAsteraceaebiology.organism_classificationComplementary and alternative medicineCaryophyllene oxideCentaureaCentaurea parilica
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Essential oil of Citrus lumia Risso: Phytochemical profile, antioxidant properties and activity on the central nervous system

2018

Citrus lumia Risso Essential oil Antioxidant properties Anti-cholinesterase activity Cytotoxicity Neuroactive effects 1. Introduction Plants that produce essential oils (EOs) represent a large part of natural flora and an important resource in various fields such as pharmaceutical, food and cosmetic industries, due to their flavor, fra- grance and biological activity (Swamy et al., 2016). EOs play a pivotal role in the growth and colonization of plants, giving color and scent to reproductive organs, attracting pollinators, favoring seed dispersion (Sharifi-Rad et al., 2017), and defending the plant against abiotic (light, temperature, etc.) and biotics (herbivores, harmful insects and pa- t…

Central Nervous System0106 biological sciences0301 basic medicineCitrusAntioxidantCytotoxicitymedicine.medical_treatmentToxicology01 natural sciencesAntioxidantsEssential oillaw.inventionTerpeneMicechemistry.chemical_compoundLinaloollawSettore BIO/15 - Biologia FarmaceuticaFood scienceCitrus lumia Risso Essential oil Antioxidant properties Anti-cholinesterase activity Cytotoxicity Neuroactive effectsbiologyGeneral MedicineNeuroprotective AgentsPhytochemicalNeuroactive effectsAnti-cholinesterase activityAcyclic MonoterpenesAntioxidant propertiesNeuroprotectionGas Chromatography-Mass SpectrometryCell Line03 medical and health sciencesCyclohexenesOils VolatilemedicineAnimalsRats WistarIC50Essential oilCholinesteraseCell-Free SystemTerpenesAnti-cholinesterase activity; Antioxidant properties; Citrus lumia Risso; Cytotoxicity; Essential oil; Neuroactive effects; Food Science; Toxicology030104 developmental biologychemistryMicroscopy Electron ScanningMonoterpenesbiology.proteinCitrus lumia RissoCholinesterase InhibitorsLimonene010606 plant biology & botanyFood ScienceFood and Chemical Toxicology
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Characterization of the transporterB0AT3 (Slc6a17) in the rodent central nervous system.

2013

Abstract Background The vesicular B0AT3 transporter (SLC6A17), one of the members of the SLC6 family, is a transporter for neutral amino acids and is exclusively expressed in brain. Here we provide a comprehensive expression profile of B0AT3 in mouse brain using in situ hybridization and immunohistochemistry. Results We confirmed previous expression data from rat brain and used a novel custom made antibody to obtain detailed co-labelling with several cell type specific markers. B0AT3 was highly expressed in both inhibitory and excitatory neurons. The B0AT3 expression was highly overlapping with those of vesicular glutamate transporter 2 (VGLUT2) and vesicular glutamate transporter 1 (VGLUT1…

Central Nervous SystemMaleSerotonin reuptake inhibitorVesicular glutamate transporter 1Central nervous systemVesicular Transport ProteinsNerve Tissue ProteinsIn situ hybridizationPharmacology and ToxicologyPharmacologyBiologyPlasma Membrane Neurotransmitter Transport ProteinsRats Sprague-DawleyCellular and Molecular NeuroscienceGlutamatergicMiceDopaminePregnancyMonoaminergicmedicineAnimalsRats WistarCells CulturedNeuronsGeneral NeuroscienceNeurosciencesTransporterFarmakologi och toxikologiEmbryo MammalianAntidepressive AgentsRatsMice Inbred C57BLProtein Transportmedicine.anatomical_structureGene Expression Regulationbiology.proteinFemaleFood DeprivationNeurovetenskapermedicine.drugResearch ArticleBMC neuroscience
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The resilience of Finnish farms: Exploring the interplay between agency and structure

2020

Resilience implies, in its essence, the capacity of a system to tolerate disturbances while retaining its essential functions. In the context of agriculture, resilience thinking calls for considering the ability of farms to thrive in turbulent times along with the ability of the ecological system – in which the agricultural production is embedded – to retain its function and integrity. Resilience is a relevant conceptual tool to analyse the contradictory management demands that farms are facing within the current neoliberal market regime: being economically viable and environmentally sustainable. In this study, the resilience of farms was operationalised through farmers' perceptions concern…

CentralisationmaatilatSociology and Political ScienceNatural resource economicsGeography Planning and Development0211 other engineering and technologies0507 social and economic geographyVulnerabilityagrifood systemContext (language use)02 engineering and technologyDevelopmentmaatilatalousfarm systemAgency (sociology)Agricultural productivityResilience (network)resilienceresilienssiruokajärjestelmätkestävä maatalous05 social sciences021107 urban & regional planningtoimijuusStructure and agencyVirtuous circle and vicious circleagency-structureBusiness050703 geographyadaptive renewal cycleJournal of Rural Studies
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Centralizēti reģistrēto bioloģisko un biolīdzīgo medikamentu reimatoīdo slimību ārstēšanai pieejamība Latvijā

2022

Bioloģiskajiem medikamentiem ir nozīmīga loma dažādu slimību terapijās, savukārt to biolīdzīgie analogi palīdz padarīt bioloģisko terapiju lētāku un pieejamāku pacientiem. Viena no slimībām, kur tiek izmantota bioloģiskā terapija, ir reimatoīdais artrīts (RA). Ja šī slimība progresē, tad nākotnē tā var novest pie nopietniem veselības traucējumiem vai pat invaliditātes, kas var radīt finansiālo slogu gan valstij, gan pacientam. Pētījumam veikšana tika izvēlētas kvantitatīvās datu ieguves metodes. Tika analizēti centralizēti reģistrēti 19 bioloģiskie un 36 biolīdzīgie medikamenti. No tiem uz RA terapiju attiecās 7 bioloģiskie un 22 biolīdzīgie medikamenti. Latvijā ir pieejami 6 bioloģiskie un…

Centralizētā reģistrācijas procedūraBiolīdzīgās zālesFarmācijaLatvijaBioloģiskās zālesZāļu pieejamība
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Correlati psicologici e biologici in una popolazione di lavoratori afferenti al Centro Anti-Mobbing di Palermo.

2011

Centro Anti-Mobbing di Palermo.correlati psicologici e biologicipopolazione di lavoratoriSettore BIO/14 - Farmacologia
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Application of molecular topology in the prediction of new compounds with anti-trypanosomal cytotoxic activity

2021

La enfermedad de Chagas es una antropozoonosis parasitaria de transmisión mayoritariamente vectorial. Si bien afecta principalmente a América, constituye una de las mayores enfermedades desatendidas a nivel mundial. Solamente dos fármacos con un alto grado de toxicidad se encuentran disponibles para su tratamiento, por lo que es preciso aunar esfuerzos en pos del desarrollo de nuevas drogas antitripanosomales eficaces y con escasos efectos adversos. En este estudio, se aplicó la topología molecular para el desarrollo de un modelo QSAR capaz de predecir la actividad citotóxica antitripanosomal de un grupo de 39 compuestos. El modelo desarrollado mediante análisis lineal discriminante permiti…

Chagas diseaseQuantitative structure–activity relationshipComputational biologyBiologyLinear discriminant analysismedicine.diseaseAntiparasiticsAntiparasitariosChagas3209 Farmacología23 QuímicamedicinePotencyMultiple linear regression analysisMolecular topologyNereis. Interdisciplinary Ibero-American Journal of Methods, Modelling and Simulation.
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Human chaperonin disease-causing mutations: study with a prokaryotic model.

2012

Chaperonopathies HspsSettore CHIM/08 - Chimica Farmaceutica
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Overdose of Quetiapine—A Case Report with QT Prolongation

2021

Quetiapine is an atypical antipsychotic drug used to treat bipolar disorder, schizophrenia, and major depressive disorder. Although several studies describe the adverse effects of intoxication with Quetiapine, only a few report an extreme overdose without comedications that lead to a life threat. We present a case of a 75-year-old male who tried to attempt suicide by ingesting 28 g of Quetiapine. During the management in the emergency department, both serum and urine samples were collected, allowing a complete pharmacokinetic analysis to be conducted, from the admission to the discharge.

Chemical Health and SafetySettore MED/43 - Medicina LegaleintoxicationChemical technologyHealth Toxicology and MutagenesisSettore BIO/14 - FarmacologiaCase ReportTP1-1185quetiapineToxicologySettore MED/25 - PsichiatriaIntoxication; QT-prolongation; QuetiapineQT-prolongationToxics
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COMPOSITION OF THE ESSENTIAL OILS IN CALENDULA SUFFRUTICOSA (ASTERACEAE) FROM SICILY

2016

The genus Calendula L. (Calenduleae Cass., Asteraceae) includes several species having medicinal properties. Pharmacological studies reveal, for instance, that C. officinalis L. exhibits antibacterial, antiviral, antinflammatory, antitumor and antioxidant properties; C. arvensis L. has antibacterial, antinflammatory, antimutagenic and haemolytic activities; C. suffruticosa Vahl has antimicrobial activity, especially against pathogenic microorganisms as Pseudomonas syringae Van Hall, Pseudomonas fluorescens (Flügge) Migula, Xanthomonas campestris (Pammel) Dowson and Agrobacterium tumefaciens Smith & Townsend. Nevertheless, despite a long tradition of use of the above species, and others,…

Chemical studySicilian populationSettore BIO/15 - Biologia FarmaceuticaChemical study; Sicilian population; Peloritani MountainsPeloritani Mountains
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