Search results for "Farmaceutica"

showing 10 items of 582 documents

Reactivity of asymmetric benzo-condensed diazines with nitrilimine dipoles in the 1,3-dipolar cycloaddition reactions

2009

The reactivity of asymmetric benzo-condensed diazines in the 1,3-dipolar cycloaddition reactions with nitrilimines was investigated. The results demonstrated that, at variance with the symmetric quinoxaline, a certain grade of diastereoselectivity emerged. Moreover in the case of the 5-methylquinoxaline and quinazoline a mono-cycloadduct was obtained.

nitrilimine dipoleChemistryNitrilimine13-dipolar cycloaddition reactionOrganic ChemistrydiazineSettore CHIM/06 - Chimica OrganicadiastereoselectivityPhotochemistrySettore CHIM/08 - Chimica FarmaceuticaBiochemistryCycloadditionchemistry.chemical_compoundDipoleQuinoxalineComputational chemistryDrug Discovery13-Dipolar cycloadditionQuinazolineReactivity (chemistry)Tetrahedron Letters
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Synthesis and antitumor activity of new 7-azaindole derivative nortopsentin analogues

2016

nortopsentin analoguesSettore CHIM/08 - Chimica Farmaceutica
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Ceiba speciosa (A. St.-Hil.) Seeds Oil: Fatty Acids Profiling by GC-MS and NMR and Bioactivity

2020

This study aimed to evaluate the chemical composition by gas chromatography-mass spectrometry (GC-MS) and Nuclear Magnetic Resonance (NMR) analyses, the antioxidant activities evaluated by different in vitro assays namely 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2&prime

obesityAntioxidantantioxidantDPPHLinoleic acidmedicine.medical_treatmentMalvalic acidPharmaceutical Science01 natural sciencesArticleAnalytical ChemistryPalmitic acidlcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologylcsh:Organic chemistryfixed oilDrug DiscoverymedicineSettore BIO/15 - Biologia FarmaceuticaPhysical and Theoretical ChemistryLipaseChromatographyABTSbiologydiabetesOrganic Chemistry04 agricultural and veterinary sciencesSettore CHIM/06 - Chimica Organicabiology.organism_classification040401 food scienceNMR0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryChemistry (miscellaneous)diabetebiology.proteinMolecular MedicineGC-MSCeiba speciosaMolecules
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Ferulago nodosa Subsp. geniculata (Guss.) Troia & Raimondo from Sicily (Italy): Isolation of Essential Oil and Evaluation of Its Bioactivity

2020

Ferulago nodosa (L.) Boiss. (Apiaceae) is a species occurring in the Balkan-Tyrrhenian area. The object of the present study is Sicilian F. nodosa subsp. geniculata (Guss.) Troia & Raimondo, classified as an endemic F. nodosa subspecies. Aerial parts of this plant species were subjected to hydrodistillation to obtain an essential oil. A total of 93 compounds were identified with 2,3,6-trimethyl benzaldehyde (19.0%), spathulenol (9.0%), (E)-caryophyllene (5.4%), and caryophyllene oxide (5.4%) as the main components. The biological activities of F. nodosa essential oil were also investigated. This oil showed an interesting antioxidant potential in a 2,2′-Azino-bis(3-ethylbenzothiazoline-6-sul…

obesityantioxidantPharmaceutical ScienceFerulago nodosaSubspeciesAntioxidant potential030226 pharmacology & pharmacy01 natural sciencesArticleessential oilAnalytical Chemistrylaw.inventionlcsh:QD241-44103 medical and health scienceschemistry.chemical_compound0302 clinical medicinelcsh:Organic chemistrylawDrug DiscoverySettore BIO/15 - Biologia FarmaceuticaPhysical and Theoretical ChemistryEssential oilApiaceaeABTSdiabetesbiologyTraditional medicineOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classificationgas chromatography-mass spectrometry0104 chemical sciences010404 medicinal & biomolecular chemistrychemistryCaryophyllene oxidediabeteChemistry (miscellaneous)Settore BIO/03 - Botanica Ambientale E ApplicataPlant speciesMolecular MedicineMolecules
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Qualitative comparision of olive oil mediterranean

2012

olive oilSettore AGR/15 - Scienze E Tecnologie AlimentariSettore CHIM/08 - Chimica FarmaceuticaSettore BIO/09 - Fisiologia
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ALLERGENS IN THE PARK AND GARDEN FLORA OF SICILY

2017

The ornamental flora of parks and gardens, as we know, generally includes high proportions of exotics. In Italy it arose from Renaissance on and increasingly enriched up to include a large proportion of exotics native to countries under Mediterranean and temperate climates. Similarly the garden flora of Sicily has a large number of mostly Mediterranean and subtropical exotics. Even if very similar on the whole, these floras differ in some floristic, biological and ecological features. Indeed, several succulent families and genera that are rare or missing in Italy are frequent in Sicily, but plants from temperate regions are almost absent in the island. As regards the allergenic patterns ref…

ornamental plants allergenic species Mediterranean and subtropical exotics pollinosisSettore BIO/03 - Botanica Ambientale E ApplicataSettore BIO/15 - Biologia Farmaceutica
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DNA binding and biological activity of Cu(II) and Zn(II) complexes of a 2,5-diphenyl[1,3,4]oxadiazole macrocycle ligand.

2011

oxadiazole DNA bindingSettore CHIM/03 - Chimica Generale E InorganicaSettore CHIM/08 - Chimica Farmaceutica
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THE ROLE OF THE CLINICAL PHARMACIST IN THE MANAGEMENT OF ANTIRETROVIRAL THERAPY

2020

Over the last few years, the Hospital Pharmacy has developed in an excellent way in Europe, proposing in many countries the clinical pharmacist as a new professional figure, and adapting its responsibilities to national health systems. The purpose of this study is to evaluate and promote the prescriptive appropriateness through the close collaboration between the pharmacist and the medical team. The aspect of the dispensation of antiretroviral therapy was deepened by providing useful information to the patient on the possible undesired effects and interactions due to the polypharmacy, on the correct way of storing the drugs, and on the importance of the regularity of the polypharmacy intake…

pharmacovigilanceinteraction of antiretroviral drugsADRs (adverse drug reactions)Settore CHIM/08 - Chimica Farmaceuticaclinical pharmacistdrug therapy appropriateness
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Synthesis and biological evaluation of some new 2-phenylpropiolamidobenzamides as potential antagonists of the HMDM2-p53 protein-protein interactions

2009

phenylpropiolamidobenzamides/antiproliferative activitySettore CHIM/08 - Chimica Farmaceutica
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Study on the mechanism of action of antitumor photochemotherapic agents by means of docking and QSPR analysis

2008

photochemotherapic agentQSPRdockingSettore CHIM/08 - Chimica Farmaceutica
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