Search results for "Fertility"

Conservative treatment of ectopic pregnancies using a single echo-guided injection of methotrexate into the gestational sac

1991

The authors describe the possibility of the conservative treatment of five early ectopic pregnancies. A single injection of methotrexate into the tubal gestational sac was performed under vaginal ultrasound guidance. In all five cases, a clear ectopic gestational sac could be visualized. The pregnancies dated from the 5th to the 7th week of amenorrhea. Strict ultrasound follow-up following injection showed a gradual reduction in the size of the tubal gestational sac. At the same time, plasma beta-hCG gradually decreased to zero after a maximum time period of 25 days. Subsequent hysterosalpingography performed on all of the women demonstrated bilateral normal patent tubes. It is concluded th…

Ethics of uterus transplantation with live donors.

2014

Ovulation induction and epigenetic anomalies

2013

In this systematic review of ovulation induction and epigenetic control, studies mainly done in the mouse model highlight how hormone treatments may be prejudicial to the epigenetic reprogramming of gametes as well as early embryos. Moreover, the hormone protocols used in assisted reproduction may also modify the physiologic environment of the uterus, a potential link to endometrial epigenetic disturbances. At present, the few available data in humans are insufficient to allow us to independently determine the impact of a woman's age and infertility problems and treatment protocols and hormone doses on such processes as genomic imprinting.

Postovulatory Aging of Oocytes Decreases Reproductive Fitness and Longevity of Offspring1

2002

We analyzed the long-term effects of postovulatory aging of mouse oocytes on reproductive fitness and longevity of offspring. Hybrid (C57BL/6JIco 3 CBA/JIco) parental generation (F0) females were artificially inseminated at 13 h (;1 h postovulation) or 22 h (;10 h postovulation) after GnRH injection. Reproductive fitness of first generation (F1) females was tested from the age of 28 wk until the end of their reproductive life. In males, the testing period ranged from the age of 2 yr until their natural death. Experimental F1 females exhibited longer between-labor intervals, decreased frequency of litters, and lower total number of litters and offspring born. Experimental second generation (…

Congenital Müllerian anomalies: a review of currently available imaging modalities

2002

Congenital uterine anomalies are associated with infertility and adverse obstetric outcomes. The sensitivity of transvaginal sonography in diagnosing these anomalies ranges from 42% to 87%. More re...

Obesity and assisted reproductive technology outcomes.

2006

Obesity is a rising health problem in Western societies. It has been related to increased morbidity and mortality rates due to several pathologies. In the field of gynaecology and reproduction, obesity is associated with menstrual disorders, hirsutism, infertility, miscarriage and obstetric complications. It is known to impair human reproduction through different mechanisms such as insulin resistance, hyperandrogenism and elevated leptin levels. Weight management and dietary intervention can reverse this situation and improve reproductive function. Obesity can also impair the outcome of assisted reproductive technologies. The lower probability of a healthy live birth described in obese wome…

Reproductive System Outcome Among Patients with Polycystic Ovarian Syndrome.

2015

Polycystic ovarian syndrome (PCOS) may present with different clinical patterns and the anovulatory phenotype may not be the most common. Data suggest that anovulation in PCOS is not the consequence of increased androgen ovarian secretion but rather of a severe derangement of early follicle development. Other mechanisms may be operative in subgroups of patients and may contribute to the arrest of follicle growth and anovulation. At least 50% of anovulatory patients with PCOS become ovulatory in their late reproductive age. There is also evidence that menopause may occur later in women with PCOS. Finally, a strategy for treatment of infertility in PCOS is presented.

Ovarian stimulation for ovulation induction and in vitro fertilization in patients with systemic lupus erythematosus and antiphospholipid syndrome.

2008

Objective To review the current evidence regarding the relationship between systemic lupus erythematosus (SLE) and antiphospholipid syndrome and female infertility, as well as the risks associated with ovarian stimulation for ovulation induction and IVF. To establish, based on this information, guidelines for safe and successful assisted reproductive technology (ART). Design A MEDLINE computer search was performed to identify relevant articles. Result(s) Systemic lupus erythematosus and antiphospholipid syndrome are not related to infertility, except for cases of amenorrhea accompanying severe flares, renal insufficiency-related hypofertility, and ovarian failure secondary to cyclophosphami…

The effect of depression and the reframing strategy on the level of satisfaction with family life in infertile and post-miscarriage couples: dyadic a…

2021

Pary zmagające się z bezpłodnością, jak i te po doświadczeniu poronienia poddawane są działaniu wielu stresorów, w obliczu których reagują lękiem, żalem i depresją, co negatywnie wpływa na płodność i wiąże się ze zwiększonym ryzykiem poronienia. Stosowanie różnych strategii radzenia sobie wydaje się mieć różny wpływ na stres związany z niepłodnością i doświadczeniami poronienia. Celem pracy było zbadanie związków miedzy depresyjnością związaną z niepłodnością i poronieniem a zadowoleniem z życia rodzinnego oraz roli stosowania strategii przekształcenia znaczenia sytuacji w przewidywaniu zadowolenia z życia rodzinnego w grupie depresyjnych par bezpłodnych oraz po doświadczeniu poronienia. W …

The heparin-glutathione test: an alternative to the hypo-osmotic swelling test to select viable sperm for intracytoplasmic sperm injection

1998

Abstract Objective: To evaluate the heparin-glutathione test (HEGLUT) for the selection of viable sperm for intracytoplasmic sperm injection (ICSI). Design: A prospective study. Setting: Department of Pediatrics, Obstetrics and Gynecology, University of Valencia and Instituto Valenciano de Infertilidad. Patient(s): Semen samples from healthy donors and patients with infertility. Intervention(s): Sperm samples were kept in culture for different periods in Ham's F-10 medium supplemented or not supplemented with heparin, reduced glutathione (GSH), or a heparin-GSH mixture. Control and heparin-GSH–treated spermatozoa were injected into hamster oocytes. The HEGLUT and ICSI were performed. Main O…