Search results for "Fiber"

showing 10 items of 2343 documents

Mesoporous inorganic nanoscale particles for drug adsorption and controlled release.

2018

The review provides an overview of the mesoporous inorganic particles employed as drug delivery systems for controlled and sustained release of drugs. We have classified promising nanomaterials for drug delivery on the basis of their natural or synthetic origin. Nanoclays are available in different morphologies (nanotubes, nanoplates and nanofibers) and they are typically available at low cost from natural resources. The surface chemistry of nanoclays is versatile for targeted modifications to control loading and release properties. Synthetic nanomaterials (imogolite, laponite and mesoporous silica) present the advantages of well-established purity and availability with size features that …

Drug CarriersMaterials sciencePharmaceutical ScienceNanoparticleImogoliteNanotechnology02 engineering and technologyMesoporous silica010402 general chemistry021001 nanoscience & nanotechnologySilicon Dioxide01 natural sciencesControlled release0104 chemical sciencesNanomaterialsNanofiberDelayed-Action PreparationsDrug deliveryClayHumansNanoparticlesAdsorption0210 nano-technologyMesoporous materialPorosityTherapeutic delivery
researchProduct

Controlled transdermal iontophoresis by ion-exchange fiber

2000

The objective of this study was to assess the transdermal delivery of drugs using iontophoresis with cation- and anion-exchange fibers as controlled drug delivery vehicles. Complexation of charged model drugs with the ion-exchange fibers was studied as a method to achieve controlled transdermal drug delivery. Drug release from the cation-exchange fiber into a physiological saline was dependent on the lipophilicity of the drug. The release rates of lipophilic tacrine and propranolol were significantly slower than that of hydrophilic nadolol. Permeation of tacrine across the skin was directly related to the iontophoretic current density and drug concentration used. Anion-exchange fiber was te…

DrugChemical PhenomenaSkin Absorptionmedia_common.quotation_subjectPharmaceutical Science02 engineering and technologyIn Vitro TechniquesPharmacologyAdministration Cutaneous030226 pharmacology & pharmacyDosage form03 medical and health scienceschemistry.chemical_compound0302 clinical medicineHumansFiberElectrodesSodium salicylateTransdermalmedia_commonMineral FibersActive ingredientChromatographyIontophoresisChemistry PhysicalIontophoresisModels Theoretical021001 nanoscience & nanotechnologyIon ExchangechemistryDrug deliveryTacrine0210 nano-technologyAlgorithmsJournal of Controlled Release
researchProduct

Ductility of Reinforced Concrete Members Externally Wrapped with Fiber-Reinforced Polymer Sheets

2007

The effectiveness of external wrapping with fiber-reinforced polymer for enhancing the curvature ductility of lightly reinforced concrete members is investigated. Referring to members with circular transverse cross sections, the performances in terms of both strength and ductility capacities are analyzed, and the predictive reliability of two different recent constitutive models, available in the literature and able to take into account the softening behavior of confined concrete, is checked. A parameter characterizing the effectiveness of the confining wrapping is proposed, and characteristic values are suggested. Moreover, referring to ductility increases due to confinement effects, a com…

Ductility; Sheets; Fiber reinforced polymers; Reinforced ConcreteMaterials sciencebusiness.industryMechanical EngineeringBuilding and ConstructionStructural engineeringFibre-reinforced plasticCurvatureductility sheets fiber reinforced polymers concrete reinforcedSettore ICAR/09 - Tecnica Delle CostruzioniComposite constructionTransverse planeMechanics of MaterialsReinforced solidCeramics and CompositesComposite materialbusinessDuctilitySofteningCivil and Structural EngineeringParametric statisticsJournal of Composites for Construction
researchProduct

Electrospinning of α,β-poly(N-2-hydroxyethyl)-dl-aspartamide-graft-polylactic acid to produce a fibrillar scaffold

2010

Abstract α,β-Poly( N -2-hydroxyethyl)- dl -aspartamide grafted with polylactic acid (PHEA- g -PLA) is a biocompatible and biodegradable amphiphilic copolymer that has been already employed to prepare a drug delivery system. In this study we have prepared for the first time a fibrillar scaffold from PHEA- g -PLA by the electrospinning of a solution of this copolymer in a mixture of N , N -dimethyl formamide (DMF) and acetone (80:20 vol/vol). The average diameter and the morphology of electrospun fibers were detected by scanning electron microscopy. Chemical degradation studies in phosphate buffer solution pH 7.4 have been performed until 15 days in order to obtain a preliminary information a…

ELECTROSPINNING PHEA PLA FIBRILLAR SCAFFOLD SCAFFOLD.Materials sciencePolymers and PlasticsOrganic ChemistryGeneral Physics and AstronomyBiomaterialElectrospinningHydrolysischemistry.chemical_compoundPolylactic acidchemistrySettore CHIM/09 - Farmaceutico Tecnologico ApplicativoNanofiberPolymer chemistryDrug deliveryMaterials ChemistryAcetoneCopolymerEuropean Polymer Journal
researchProduct

Lesion load may predict long-term cognitive dysfunction in multiple sclerosis patients

2015

Background: Magnetic Resonance Imaging (MRI) techniques provided evidences into the understanding of cognitive impairment (CIm) in Multiple Sclerosis (MS). Objectives: To investigate the role of white matter (WM) and gray matter (GM) in predicting long-term CIm in a cohort of MS patients. Methods: 303 out of 597 patients participating in a previous multicenter clinical-MRI study were enrolled (49.4% were lost at follow-up). The following MRI parameters, expressed as fraction (f) of intracranial volume, were evaluated: cerebrospinal fluid (CSF-f), WM-f, GM-f and abnormal WM (AWM-f), a measure of lesion load. Nine years later, cognitive status was assessed in 241 patients using the Symbol Dig…

EMTREE medical terms: Articlerecalllcsh:MedicineAudiologyNeuropsychological TestsNerve Fibers Myelinated030218 nuclear medicine & medical imagingCohort Studies0302 clinical medicinecognitive defectnuclear magnetic resonance imaginglcsh:ScienceModified Card Sorting TestMultidisciplinaryneuroimagingSemantically Related Word List TestMultiple Sclerosis Cognitive Dysfunction MRImedicine.diagnostic_testpredictive valueBrainCognitionNeuropsychological testgray matterMiddle AgedPrognosisMagnetic Resonance ImagingMemory Short-Termfemalebrain sizemultiple sclerosiCohortDisease ProgressionSettore MED/26 - Neurologiawhite matterResearch ArticleAdultmedicine.medical_specialtyMultiple SclerosisPaced Auditory Serial Addition Testverbal memorycerebrospinal fluidworking memory03 medical and health sciencesmalemedicineHumanscontrolled studyhumanRecallbusiness.industryMultiple sclerosislcsh:RMagnetic resonance imagingmedicine.diseasemajor clinical studyattentionexecutive functionSymbol Digit Modalities TestPaced Auditory Serial Addition Testneuropsychological testlcsh:QVerbal memorybusinessCognition Disorders030217 neurology & neurosurgeryFollow-Up Studies
researchProduct

Surface debris of canal walls after post space preparation in endodontically treated teeth: A scanning electron microscopic study

2004

Abstract Purpose To evaluate surface cleanliness of root canal walls along post space after endodontic treatment using 2 different irrigant regimens, obturation techniques, and post space preparation for adhesive bonding. Study design Forty teeth, divided into 4 groups, were instrumented, using Ni-Ti rotary files, irrigated with NaOCl or NaOCl + EDTA and obturated with cold lateral condensation (CLC) or warm vertical condensation (WVC) of gutta-percha. After post space preparation, etching, and washing procedure, canal walls were observed using a scanning electron microscope (SEM). Amount of debris, smear layer, sealer/gutta-percha remnants, and visibility of open tubules were rated. Result…

EUGENOLMaterials scienceAdhesive bondingSodium HypochloriteSurface PropertiesRoot canalIRRIGANTSSmear layerDentistryRoot Canal Filling MaterialsSODIUM-HYPOCHLORITEAcid Etching DentalRoot Canal ObturationIRRIGATIONDentinmedicineHumansRETENTIONFIBER POSTSZinc Oxide-Eugenol CementROOT CANALSGeneral DentistryEdetic AcidDental Pulp CavityTooth NonvitalRoot Canal ObturationbiologyRoot Canal Irrigantsbusiness.industryTooth PreparationGutta-perchabiology.organism_classificationSEALERSRoot Canal Therapymedicine.anatomical_structureOtorhinolaryngologyDentinGuttaMicroscopy Electron ScanningSurgeryOral SurgeryDental Pulp CavityGutta-PerchabusinessRESIN CEMENTSMEAR LAYERRoot Canal PreparationPost and Core Technique
researchProduct

The Bimodal Distribution in Exoplanet Radii: Considering Varying Core Compositions and $\rm H_{2}$ Envelope's Sizes

2020

Several models have been introduced in order to explain the radius distribution in exoplanet radii observed by Fulton et al. (2017) with one peak at $\rm \sim 1.3 R_{\oplus} $ the other at $\rm \sim 2.4 R_{\oplus} $ and the minimum at $\rm \sim 1.75R_{\oplus} $. In this paper we focus on the hypothesis that the exoplanet size distribution is caused by stellar XUV-induced atmospheric loss. We evolve $10^{6}$ synthetic exoplanets by exposing them to XUV irradiation from synthetic ZAMS stars. For each planet we set a different interior composition which ranged from $\rm 100 \: wt\%$ Fe (very dense) through $\rm 100 \: wt\%$ $\rm MgSiO_{3}$ (average density) and to $\rm 100 \: wt\%$ $\rm H_{2}O…

Earth and Planetary Astrophysics (astro-ph.EP)PhysicsFOS: Physical sciencesAstronomy and AstrophysicsAstrophysicsExoplanetCore (optical fiber)Distribution (mathematics)Astrophysics - Solar and Stellar AstrophysicsSpace and Planetary ScienceAstrophysics::Earth and Planetary AstrophysicsSolar and Stellar Astrophysics (astro-ph.SR)Envelope (waves)Astrophysics - Earth and Planetary Astrophysics
researchProduct

Vibrations of a continuous web on elastic supports

2017

We consider an infinite, homogenous linearly elastic beam resting on a system of linearly elastic supports, as an idealized model for a paper web in the middle of a cylinder-based dryer section. We obtain closed-form analytical expressions for the eigenfrequencies and the eigenmodes. The frequencies increase as the support rigidity is increased. Each frequency is bounded from above by the solution with absolutely rigid supports, and from below by the solution in the limit of vanishing support rigidity. Thus in a real system, the natural frequencies will be lower than predicted by commonly used models with rigid supports. peerReviewed

Elastic beamGeneral MathematicsAerospace EngineeringOcean EngineeringRigidity (psychology)02 engineering and technologySection (fiber bundle)0203 mechanical engineeringCylinderLimit (mathematics)viscoelasticityCivil and Structural EngineeringPhysicsta214Analytical expressionsMechanical EngineeringMathematical analysista111021001 nanoscience & nanotechnologyCondensed Matter Physicsstructural dynamicstärinäVibration020303 mechanical engineering & transportsClassical mechanicsMechanics of MaterialsBounded functionAutomotive Engineeringelasticitydynamics of machinesvibration0210 nano-technologyMechanics Based Design of Structures and Machines
researchProduct

Analytical design of dispersion-managed fiber systems with S ≈ 1.65

2002

We present an easy analytical method for designing dispersion-managed fiber systems with map strength of 1.65, where the transmission lines have minimal pulse-pulse interactions.

Electric power transmissionComputer scienceFiber (mathematics)Dispersion (optics)Electronic engineeringDispersion managedAnalytical designRange findingNonlinear Guided Waves and Their Applications
researchProduct

Generation of optical domain-wall structures from modulational instability in a bimodal fiber.

1998

We study experimentally modulational instability in a normally dispersive bimodal fiber under modal group-velocity-matching conditions. In the strong pump depletion regime, higher order sideband harmonics detected in the output spectra as well as autocorrelation measurements reveal the formation of subpicosecond domain-wall structures. Across these temporal structures the electromagnetic field distribution switches abruptly between the two transverse modes of the fiber. These structures are reminiscent of the so-called domain-wall soliton. Our results constitute therefore an experimental indication of the existence of this fundamental soliton.

Electromagnetic fieldPhysicsModulational instabilityTransverse planeOpticsDomain wall (magnetism)Sidebandbusiness.industryHarmonicsFiberSolitonbusinessMolecular physicsPhysical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics
researchProduct