Search results for "Fires"
showing 10 items of 129 documents
Stretching of Free Chains Confined in Concave Brush-Coated Nanocylinders
2012
The structure of a free flexible macromolecule confined in a cylindrical nanopore whose wall is coated by a polymer brush is studied by Monte Carlo simulation, varying the grafting density as well as the radius of the cylindrical pore. Because of this confinement, the free chain is stretched in axial direction; while for small grafting densities of the brush the end-to-end distance increases monotonously with decreasing pore radius, a nonmonotonic variation occurs for larger grafting densities. We show that this effect is due to strong interpenetration of the free chain and the brush chains; for very narrow pores a strong layering of cylindrical shells is found, and comparison with self-con…
Bioadhesive monolayer film for the in vitro transdermal delivery of sumatriptan
2006
The work presented here aims to develop a bioadhesive monolayer film containing sumatriptan as adjuvant for the treatment of headache pain in a severe migraine attack. Permeation experiments were performed from the films prepared and from the respective solution, to evaluate the relevant permeation parameters. The effect of the penetration enhancers Transcutol, 2-pyrrolidone, and polyethylene glycol 600 was evaluated. The results obtained show that Transcutol and 2-pyrrolidone decreased sumatriptan permeation from solution, whereas a modest increase was produced by polyethylene glycol 600. The enhancers produced the same effects when they were included in the film. Compared to solution, the…
The digital outcry: What incites participation behavior in an online firestorm?
2017
Brands, celebrities, or politicians are increasingly facing enormous online outrages in response to moral misconducts. These online firestorms are characterized by high message volume, indignant tonality, and negative opinion climate. Based on the concept of moral panics, this article analyzes why people join online firestorms. We argue that participation behavior is driven by a moral compass and a desire for social recognition. Results of an experiment and a content analysis of user comments show that a higher number of participants decreases users’ willingness to participate but fosters compliance with the prevalent opinion and tonality of the comments. We also observe that a higher mora…
Voltage Profile Improvement for Soc Son's Low-Voltage Grid with High Penetration of PV Systems by Optimizing the Location of SVC Devices
2018
This paper presents a method that is applied to optimize the placement of Static VAR compensators in a real low-voltage grid in the Vietnamese territory. In this way, the voltage profile of the distribution grid turns to be improved. A heuristic method, the Binary Particle Swarm Optimization, is used to find a solution to this problem within the Matlab environment. A case study that considers a high penetration of rooftop PV systems in a branch of Soc Son distribution grid is implemented to show the efficiency of the optimization method for this specific application.
Microparticles derived from marine sponge collagen (SCMPs): preparation, characterization and suitability for dermal delivery of all-trans retinol.
2002
Abstract Collagen microparticles were prepared using marine sponge collagen. For this purpose a previous method by Rossler et al. (J. Microencapsul. 12 (1995) 49) of emulsification and cross-linking of native calf collagen was modified. The modified method for sponge collagen microparticles (SCMPs) achieved a yield of 10%. Scanning electromicroscopic photographs showed spherical particles with a diameter of 120–300 nm and photon correlation spectroscopic measurements indicated particle size range from 126 (±2.9) to 2179 (±342) nm. This broad size distribution was caused by some agglomerates that could not be destroyed by ultrasonication. The surface charge was measured as a function of pH. …
Universal relationship between the penetration depth and the normal-state conductivity in YBaCuO
1999
The absolute values of the conductivity in the normal state sigma_n and of the low temperature penetration depths lambda(0) were measured for a number of different samples of the YBaCuO family. We found a striking correlation between sigma_n and 1/lambda^2, regardless of doping, oxygen reduction or defects, thus providing a simple method to predict the superconducting penetration depth and to have an estimate of the sample quality by measuring the normal-state conductivity.
The Role of Fire in Achieving the Sustainable Development Goals of the United Nations
2019
The Sustainable Development Goals (SDGs) of the United Nations do not mention Fire as a key factor in achieving an environmentally-friendly human society. This paper reviews the key aspects of the impact of fire that make it necessary to update the SDGs. Upon reviewing the scientific literature, it was found that fire has been part of the Earth System for the last 400 million years, and that it is part of biogeochemical cycles. From a geological perspective, fire shaped the current Earth System. Humans have used fire in the last million years as hunter-gatherers, and the last Pleistocene period evolved with the presence of fire. Since the Neolithic revolution, humankind spread the use of fi…
Transcutol containing vesicles for topical delivery of minoxidil
2010
The aim of this work was to evaluate the ability of Transcutol (Trc) to produce elastic vesicles with soy lecithin (SL) and study the influence of the obtained vesicles on in vitro (trans)dermal delivery of minoxidil. To this purpose, so-called penetration enhancer-containing vesicles (PEVs) were prepared using Trc aqueous solutions (5-10-20-30% v/v) as hydrophilic phase. SL liposomes, without Trc, were used as control. Prepared formulations were characterized in terms of size distribution, morphology, zeta potential, deformability, and rheological behavior. The influence of the obtained PEVs on (trans)dermal delivery of minoxidil was studied by in vitro diffusion experiments through pig sk…
Nortriptyline for smoking cessation: Release and human skin diffusion from patches
2009
Abstract The objective of this work was to develop a simple and inexpensive transdermal formulation containing Nortriptyline Hydrochloride (NTH) for smoking cessation support therapy. Hydroxypropyl-methyl-cellulose was chosen as polymer and a mixture of transdermal enhancers (selected from previous research) was incorporated. The formulations were characterised in terms of appearance, thickness, uniformity of NTH content, release and skin permeation. Release studies demonstrated controlled release for four formulations. Diffusion studies were performed through human heat separated epidermis (HHSE) using Franz Diffusion Cells (FDC). Patches provided different fluxes varying from 20.39 ± 7.09…
Exposure assessment of a burning ground for chemical ammunition on the Great War battlefields of Verdun
2007
The destruction of arsenical shells from the 1914/18 war in the vicinity of Verdun (France) during the 1920s resulted in a locally limited but severe soil contamination by arsenic and heavy metals. At the study site, the main part of the contaminant inventory occurs in the upper 20 cm of the topsoil which is essentially composed of combustion residues. Besides, some Cu (cmax.=16,877 mg/kg) and Pb (cmax.=26,398 mg/kg) in this layer, As (cmax.=175,907 mg/kg) and Zn (cmax.=133,237 mg/kg) were detected in very high concentrations. The mobilities of Cu, Mn, Pb and Zn in the soil system were derived from ammonium nitrate eluates. They are strongly influenced by the soil pH and can be described by…