Search results for "Fora"

showing 10 items of 1086 documents

Alteraciones en la homeostasis del transportador de glutamato GLT-1 en la Enfermedad de Lafora

2017

Tesis doctoral, 192 páginas, figuras y tablas

GLT-1transporte glutamatoGlutamatoUbicuitinaciónglutamatoubicuitinaciónendocitosisTransporte glutamatoLaforaEAAAT2EndocitosisepilepsiaEpilepsia
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Moderately close Neumann inclusions for the Poisson equation

2016

We investigate the behavior of the solution of a mixed problem for the Poisson equation in a domain with two moderately close holes. If ϱ1 and ϱ2 are two positive parameters, we define a perforated domain Ω(ϱ1,ϱ2) by making two small perforations in an open set: the size of the perforations is ϱ1ϱ2, while the distance of the cavities is proportional to ϱ1. Then, if r∗ is small enough, we analyze the behavior of the solution for (ϱ1,ϱ2) close to the degenerate pair (0,r∗). Copyright © 2016 John Wiley & Sons, Ltd.

General Mathematics010102 general mathematicsMathematical analysisGeneral Engineeringmixed problem; moderately close holes; Poisson equation; real analytic continuation in Banach space; singularly perturbed perforated domain; Mathematics (all); Engineering (all)Poisson equation01 natural sciences010101 applied mathematicsmixed problemsingularly perturbed perforated domainEngineering (all)Settore MAT/05 - Analisi MatematicaMathematics (all)0101 mathematicsPoisson's equationmoderately close holesMathematicsreal analytic continuation in Banach space
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Effects of histamine on dentate granule cells in vitro

1990

Abstract Hippocampal slices from rat brain were exposed to histamine and related substances in a perfusion chamber. Granule cells of the dentate gyrus were studied with conventional extra- and intracellular recording and a single electrode voltage clamp. Histamine caused, through activation of H 2 -receptors, a small depolarization, an increase in the number of synaptic and action potentials, a block of the long lasting (but not the early) component of spike afterhyperpolarizations and a reduction of the accommodation of action potential firing. These effects were mimicked by forskolin (suggests activation of adenylate cyclase). In voltage clamp, histamine blocked a long lasting calcium-dep…

General NeuroscienceDentate gyrusColforsinHistaminergicAction PotentialsRats Inbred StrainsIn Vitro TechniquesPerforant pathInhibitory postsynaptic potentialHippocampusMembrane PotentialsRatschemistry.chemical_compoundmedicine.anatomical_structurechemistryHistamine H2 receptormedicineExcitatory postsynaptic potentialBiophysicsAnimalsHistamine H3 receptorNeuroscienceHistamineAdenylyl CyclasesHistamineNeuroscience
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Diseased Social Predators

2017

Social predators benefit from cooperation in the form of increased hunting success, but may be at higher risk of disease infection due to living in groups. Here, we use mathematical modeling to investigate the impact of disease transmission on the population dynamics benefits provided by group hunting. We consider a predator-prey model with foraging facilitation that can induce strong Allee effects in the predators. We extend this model by an infectious disease spreading horizontally and vertically in the predator population. The model is a system of three nonlinear differential equations. We analyze the equilibrium points and their stability as well as one- and two-parameter bifurcations. …

Genetics and Molecular Biology (all)0106 biological sciences0301 basic medicinegenetic structuresPopulation DynamicsBasic Reproduction NumberBiochemistry01 natural sciencesCommunicable DiseasePredationMathematical modelBehavioral ecologyCooperative BehaviorPredatorMathematical ConceptGeneral Environmental ScienceAllee effectBehavioral ecology; Eco-epidemiology; Foraging facilitation; Group living; Hunting cooperation; Mathematical model; Neuroscience (all); Immunology; Mathematics (all); Biochemistry Genetics and Molecular Biology (all); 2300; Pharmacology; Agricultural and Biological Sciences (all); Computational Theory and Mathematicseducation.field_of_studyEco-epidemiologyEcologyGeneral Neuroscience010601 ecologyGroup livingComputational Theory and MathematicsFacilitationsymbolsLinear ModelGeneral Agricultural and Biological SciencesFood ChainGeneral MathematicsPopulationForagingImmunologyBehavioral ecologyBiologyCommunicable DiseasesModels BiologicalGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencessymbols.namesakeSettore MAT/08 - Analisi NumericaAnimalsMathematics (all)educationSocial BehaviorPharmacologyPopulation DynamicNeuroscience (all)Biochemistry Genetics and Molecular Biology (all)2300AnimalHunting cooperationSmall population sizeMathematical Concepts030104 developmental biologyForaging facilitationAgricultural and Biological Sciences (all)Predatory BehaviorLinear Models
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Reconstruction of the environmental evolution of a Sicilian saltmarsh (Italy)

2013

The present study deals with the reconstruction of the environmental evolution of a Trapani saltmarsh (southwestern Sicily, Italy) by combining different analytical approaches such as metal content evaluation, low-field nuclear magnetic resonance (NMR) relaxometry, and benthic foraminifera identification. A 41 cm core was collected in the sediments of a Trapani saltmarsh (southwestern Sicily, Italy) at a water depth of about 50 cm. Different time intervals were recognized, each characterized by peculiar features that testify different environmental conditions. In particular, the bottom layers of the sediment core (41–28 cm) comprised the lowest amount of mud fraction, only some selected met…

Geologic SedimentsGypsumMagnetic Resonance SpectroscopyHealth Toxicology and MutagenesisForaminiferaengineering.materialForaminiferaEnvironmental reconstructionEnvironmental ChemistryEcosystemSeawaterSicilygeographygeography.geographical_feature_categorySaltmarshbiologyMetal analyseBenthic foraminiferaSedimentGeneral Medicinebiology.organism_classificationPollutionlanguage.human_languageOceanographyAmmonia tepidaBenthic zoneSalt marshWetlandslanguageengineeringFFC-NMR. RelaxometrySicilianGeologyWater Pollutants ChemicalEnvironmental Monitoring
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Benthic foraminiferal response to trace element pollution. The case study of the Gulf of Milazzo, NE Sicily (Central Mediterranean Sea).

2013

The response of benthic foraminiferal assemblages to trace element pollution in the marine sediments of the Gulf of Milazzo (north-eastern Sicily) was investigated. Since the 1960s, this coastal area has been a preferred site for the development of two small marinas and a commercial harbour as well as for heavy industry. Forty samples collected in the uppermost 3-4 cm of an undisturbed layer of sediment in the littoral environment were used for this benthic foraminiferal analysis. The enrichment factors (EFs) of selected trace elements (As, Co, Cr, Cu, Mn, Ni, Pb and Zn) were also calculated. Changes both in benthic foraminiferal assemblages and in some trace elements concentrations have pr…

Geologic SedimentsNorth-Earstern Sicilian coastForaminiferaManagement Monitoring Policy and LawMarine pollutionForaminiferaAberrant testMediterranean seaMediterranean SeaWater Pollution ChemicalLittoral zoneSeawaterSicilyGeneral Environmental ScienceGulf of MilazzoTrace element pollutionbiologyBenthic foraminiferaTrace elementSpecies diversitySedimentGeneral MedicineOffshore northern Sicilybiology.organism_classificationPollutionTrace ElementsOceanographyBenthic zoneTrace elementSpecies richnessWater Pollutants ChemicalGeologyEnvironmental Monitoring
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Morpho-physiological and adaptive variation of Italian germplasm of sulla (Hedysarum coronarium L.)

2014

Sulla is a biennial forage legume native to the central-western Mediterranean Basin and has increasing interest for regions with Mediterranean-climate. The Italian germplasm is a reservoir of variation for important agronomic traits. This study aimed to support breeding programs by investigating patterns of agronomic, adaptive and morpho-physiological variation among ecotypes collected from the three main Italian regions of species cultivation: central Italy, and the two islands of Sicily and Sardinia. Forage yield and morpho-physiological traits were evaluated at a site with Mediterranean climate in Sicily. Forage yield and cold tolerance in a cold-prone site of northern Italy were also as…

GermplasmMediterranean climategeographyAnimal breedinggeography.geographical_feature_categoryEcotypeEcologycold tolerance genetic structure genetic resources plant adaptation seed yieldForagePlant ScienceBiologyMediterranean BasinPastureSettore AGR/02 - Agronomia E Coltivazioni ErbaceeAgronomyPlant breedingAgronomy and Crop Science
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Teratogenicity and Developmental Toxicity of Herbal Products

2017

Developmental toxicology and research in teratogenicity focus on xenobiotic substances that damage embryos and fetuses and lead to death, growth retardation, and/or malformation of offspring. While considerable information has been acquired about synthetic drugs and environmental xenobiotics, much less is known about the teratogenicity of herbal products. In this chapter we report on some major topics of developmental toxicity and teratogenicity, and discuss the safety of a few selected medicinal herbs in this context, i.e., Artemisia annua L., Caulophyllum thalictroides (L.) Michx., Echinacea spec,. Glycyrrhiza spec., herbs derived from Chinese medicine, Hypericum perforatum L., Panax gins…

GinsengValeriana officinalisbiologyTraditional medicineDevelopmental toxicityArtemisia annuafood and beveragesHypericum perforatumGlycyrrhizaContext (language use)Traditional Chinese medicinebiology.organism_classificationcomplex mixtures
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The bivalve <i>Glycymeris planicostalis</i> as a high-resolution paleoclimate archive for the Rupelian (Early Oligocene) …

2015

Abstract. Current global warming is likely to result in a unipolar glaciated world with unpredictable repercussions on atmospheric and oceanic circulation patterns. These changes are expected to affect seasonal extremes and the year-to-year variability of seasonality. To better constrain the mode and tempo of the anticipated changes, climatologists require ultra-high-resolution proxy data of time intervals in the past, e.g., the Oligocene, during which boundary conditions were similar to those predicted for the near future. In the present paper, we assess whether such information can be obtained from shells of the long-lived bivalve mollusk Glycymeris planicostalis from the late Rupelian of…

Global and Planetary ChangeGlycymerisbiologyStratigraphyGlobal warmingPaleontologyStructural basinPlanktonSeasonalitybiology.organism_classificationmedicine.diseaseForaminiferaSea surface temperatureOceanographyClimatologyPaleoclimatologymedicineGeologyClimate of the Past
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Regulación de la homeostasis del glucógeno: el papel de R6 y la enfermedad de Lafora

2016

El glucógeno es la principal reserva de energía en nuestras células y es una molécula esencial para nuestro cerebro. Sin embargo, muchas cuestiones sobre el complejo metabolismo de este carbohidrato siguen por elucidar. Un paso clave en la regulación de la homeostasis del glucógeno es el llevado a cabo por la proteína fosfatasa de tipo 1, PP1. PP1 es capaz de estimular la síntesis de glucógeno mediante la desfosforilación de dos enzimas clave: la glucógeno sintasa (GS) y la glucógeno fosforilasa (GP). La fosfatasa necesita unirse a subunidades reguladoras para el reconocimiento de los diferentes sustratos. En el metabolismo del glucógeno, se han descrito hasta la fecha 7 de estas subunidade…

GlucógenoEnfermedad de LaforaMetabolismoNeurodegeneraciónUNESCO::CIENCIAS DE LA VIDAR6PP1:CIENCIAS DE LA VIDA [UNESCO]Epilepsia
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