Search results for "Format"
showing 10 items of 24643 documents
Light on the molecular and cellular mechanisms of bicuspid aortic valve to unveil phenotypic heterogeneity
2019
Research on bicuspid aortic valve disease (BAV) and related complications has grown in an exponential manner in the last decades. However, the current knowledge of the mechanisms underlying the development of this disease is still limited, since all clinical and surgical studies on BAV mainly focused their objects on its major vascular complications, such as ascending aortic aneurysms and dissection. It is now clear that a better understanding of the pivotal molecular and cellular pathophysiological aspects of bicuspid valve aortopathy, including natural history, phenotypic expression, histology, cellular mechanisms and pathways, is critical for improving its clinical management. This chang…
Chemoselective, Substrate-directed Fluorination of Functionalized Cyclopentane β-Amino Acids
2016
This work describes a substrate-directed fluorination of some highly functionalized cyclopentane derivatives. The cyclic products incorporating CH2 F or CHF2 moieties in their structure have been synthesized from diexo- or diendo-norbornene β-amino acids following a stereocontrolled strategy. The synthetic study was based on an oxidative transformation of the ring carbon-carbon double bond of the norbornene β-amino acids, followed by transformation of the resulted "all cis" and "trans" diformyl intermediates by fluorination with "chemodifferentiation".
On-Surface Reactions
2015
On-surface synthesis constitutes a rapidly growing field of research due to its promising application for creating stable molecular structures on surfaces. While self-assembled structures rely on reversible interactions, on-surface synthesis provides the potential for creating long-term stable structures with well-controlled properties, for example superior electron transport for future molecular electronic devices. On-surface synthesis holds the promise for preparing insoluble compounds that cannot be produced in solution. Another highly exciting aspect of on-surface synthesis is the chance to discover new reaction pathways due to the two-dimensional confinement of the reaction educts. In …
Monetary information in sustainability reports: How is it related with stakeholders?
2014
Sustainability reports have recently become a central tool for a corporation in convincing different stakeholder of their sustainability performance. The research and especially criticism towards sustainability reports is increasing. One solution for the criticism would be that companies provide more monetary arguments of their sustainability work. Currently there is a research gap of the content of the monetary sustainability reporting. This paper aims to address this gap by analysing how three Finnish companies construct the classification of stakeholders in terms of monetary information in their sustainability reports between 2003 and 2012. We studied three Finnish companies which repres…
Introduction to next-generation engineering: Being human in the information society
2022
While adopting Information Technology (IT) may have been a goal in itself in the past, during the last decade the emphasis has shifted, and IT has instead become a tool that enables us to realize other needs. This also sets new requirements for IT education: skills in software engineering and computer science alone do not provide students with the professional abilities they will need after graduation. To answer this call, the University of Jyväskylä launched in autumn 2021 a new engineering B.Sc. and M.Sc. degree program in Information and Software Engineering with close ties to the Humanities. The degree program was established on three cornerstones: 1) the ability to implement IT systems…
Archaeometric characterization and 3D survey: new perspectives for monitoring and valorization of Morgantina silver Treasure (Sicily)
2015
The Morgantina silver Treasure belonging to the collections of the Archaeological Museum of Aidone (Sicily) were involved in a 3D survey and diagnostics campaign for monitoring over time of the finds, in anticipation of their temporary transfer to the Metropolitan Museum of Art in New York, for a period of four years. According to a multidisciplinary approach, it has been developed a scientific and methodological protocol based on non-invasive techniques to achieve a complete and integrated knowledge of the precious items, of their conservation state and increasing their valorisation. All acquired data, i.e. 3D models, UV fluorescence and X-Ray images and chemical information, will be made …
Some Contributions to the Algebraic Theory of Automata
2015
En el present treball estudiarem els autòmats des d'una perspectiva tant algebraica com coalgebraica. Volem aprofitar la natura dual d'aquests objectes per a presentar un marc unificador que explique i estenga alguns resultats recents de la teoria d'autòmats. Per tant, la secció 2 conté nocions i definicions preliminars per a mantenir el treball tan contingut com siga possible. Així, presentarem les nocions d'àlgebra i coàlgebra per a un endofunctor. També introduirem alguns conceptes sobre monoides i llenguatges. En aquest capítol també exposarem les nocions d'autòmats deterministes i no deterministes, homomorfismes i bisimulacions d'autòmats i productes i coproductes d'aquestes estructure…
About time
2019
Purpose The purpose of this paper seeks to develop a motivation-based complementary framework for temporally dynamic user preferences to facilitate optimal timing in web personalisation. It also aims to highlight the benefits of considering user motivation when addressing issues in temporal dynamics. Design/methodology/approach Through theory, a complementary framework and propositions for motivation-based temporal dynamics for further testing are created. The framework is validated by feeding back findings, whereas some of the propositions are validated through an experiment. Findings The suggested framework distinguishes two ways (identifying/learning and shifting) of using a motive-base…
Curiosity and exploration: A conceptual overview and structural modeling
2001
Many attempts have been made to measure curiosity or intrinsic motivation. However, there is no consensus on what curiosity is. In the present study, five previously constructed curiosity inventories were translated to Finnish and modified to be convenient for fifth-graders. The main purpose of the study was to clarify the concept of curiosity. Using conceptual analysis and the results of previous studies, it was possible to construct nine alternative conceptual models of curiosity. The corresponding statistical models were expected to account for the covariances among 15 subscales measuring curiosity-related exploratory behavior. However, before proceeding to the subscale level, the struct…
Henkilöstön tietoturvakäyttäytyminen yrityskontekstissa
2016
Tämä tutkielma on toteutettu kirjallisuuskatsauksena, jonka lähteinä on käytet-ty pääasiassa akateemisten julkaisujen artikkeleita. Tutkielman tarkoitus oli sel-vittää mitä on tietoturvakäyttäytyminen, tekijät jotka vaikuttavat henkilöstön tietoturvakäyttäytymiseen ja miten henkilöstön käyttäytymistä voitaisiin paran-taa, tietoturvan säilyttämiseksi. Kirjallisuuden perusteella onnistuttiin löytä-mään kattava lista erilaisia käyttäytymisen vaikuttavia tekijöitä ja henkilöstön motivoinnin keinoja. Näistä tekijöistä ja keinoista muodostettiin kontribuutiona havainnollistava kuva, sekä konkreettinen tehtävälista. This thesis is a literature review based mainly on academic publications. Mean-ing…