Search results for "Forming"
showing 10 items of 1719 documents
GARP: A Key Target to Evaluate Tumor Immunosuppressive Microenvironment
2021
Simple Summary Tumors are not only composed of cancer cells but also of various infiltrating cells constituting the tumor microenvironment (TME); all these cells produce growth factors which contribute to tumor progression and invasiveness. Among them, transforming growth factor-β1 (TGF-β1) has been shown to be a potent immunosuppressive cytokine favoring cell proliferation and invasion and to be associated with resistance to anticancer treatments. Glycoprotein-A repetition predominant (GARP) plays a critical role in the activation of TGF-β1 and has been shown to be expressed at the membrane of cancer cells and also of regulatory T cells and platelets in the TME. An increased GARP expressio…
Leadership in an online multiplayer strategy game: case – Illuria
2011
This paper looks at leadership communication in the context of online multiplayer games and the groups that operate within them. In multiplayer games promoting teamwork and long-term cooperation, issues of management and leadership are prevalent. The study explores the experiences that members of multiplayer communities have towards leadership in multiplayer games by looking at one specific case of organised team play within the framework of a turn-based online strategy game. The data utilised in this study consist of themed player interviews conducted via e-mail. The analysis proposes three central dimensions that emerged from the data. These were labelled: (1) the leader as primus motor, …
The Illegible Doctor’s Writing as a Visual Artifact and Creative Stimulation for Art Education
2014
El presente artículo analiza las posibilidades educativas de la particular escritura de los médicos, estudiando la componente gráfica de sus documentos, tanto históricos como recientes. Defendemos la escritura manual como un elemento gráfico importante para la educación artística, a partir de las premisas de la cultura visual. Nos basamos en los resultados positivos de la exposición “Caligrafías de la enfermedad. Letra de médico”, una muestra en la que los visitantes son protagonistas, intérpretes y constructores de significados. Utilizamos la metodología de los estudios de caso, incorporando la observación directa de varios grupos de visitantes. También aportamos otros datos de la experien…
Goethe's scenography drawings
2017
[EN] Goethe’s facet of playwright and theater manager guarantee his architectural knowledge on these issues shown in his drawings. In its stage proposals he left the Vitruvian and Palladian models, followed in the typological definition, eliminating the architectural frons scænæ frons and preferring sets painted. Thus, fictitious architecture fit each representation but it differed from building’s architecture appropriateness.
Single-Point Incremental Forming of Titanium and Titanium Alloy Sheets.
2021
Incremental sheet forming of titanium and its alloys has a significant role in modern manufacturing techniques because it allows for the production of high-quality products with complex shapes at low production costs. Stamping processes are a major contributor to plastic working techniques in industries such as automotive, aerospace and medicine. This article reviews the development of the single-point incremental forming (SPIF) technique in titanium and its alloys. Problems of a tribological and microstructural nature that make it difficult to obtain components with the desired geometric and shape accuracy are discussed. Great emphasis is placed on current trends in SPIF of difficult-to-fo…
Collaborative Musical Creativity between Students and Adults: The Sonorous Paella
2021
While creativity is a key element of contemporary curriculum frameworks around the world, it is still insufficiently fostered in formal education settings. This study analyzes a project for collaborative musical creativity, entitled The Sonorous Paella. Participants (N = 12) were eight Year 4 secondary students, two professional musicians, an artist-in-residence, and a music teacher. Drawing on a graphic musical score, the participants worked together for 1.5 months to produce a group composition and performance. They were provided with various sound producers (instruments, everyday objects, technological devices) and were encouraged to flexibly utilize the physical space to maximize collab…
LA FÍSICA TEÓRICA BAJO EL FOCO DE LO FANTÁSTICO: UNA REFLEXIÓN SOBRE LO REAL Y SUS FRACTURAS EN EL DISCURSO CIENTÍFICO
2018
Quite often fantastic literature has been studied using ideas from theoretical physics in order to verify how the development of the latter modifies the reader's perception of the former. Instead, this article proposes the opposite: this article will explore theoretical physics using the ideas from the fantastic. The core principle here is that both reflect on the reality and fracture it, changing the reader's reality paradigm. While physics changes it from reality, using to it the principles of the mathematics, the fantastic does this using (and fracturing) a fictional space.
La scoperta, sistemazione e conservazione della grande Iscrizione di Gortina, nell'isola di Creta (1884-1921): la protezione delle testimonianze e le…
2013
La scoperta e la conservazione della Grande Iscrizione di Gortina a Creta, da parte degli studiosi italiani, fra la fine del XIX sec. e i primi decenni del XX sec., rappresentò un grande riconoscimento scientifico-culturale per la giovane nazione italiana. Nel passato, l’isola di Creta era stata legata alla Repubblica di Venezia e anche questo rapporto favorì l’invio a Creta del giovane epigrafista F. Halbherr, il quale fra notevoli peripezie rinvenne, assieme all’epigrafista tedesco E. Fabricius, la famosa l’iscrizione nell’antica città di Gortina. L’iscrizione, fra le più antiche e complete finora conosciute in tutta Europa, conteneva le norme sulla famiglia, l’eredità e in generale i dir…
Reimparare il comune: A teatro dopo il 1989
2020
L'articolo coglie l’invito a recarsi a teatro con una domanda in mente: in che misura la data ‘spartiacque’ del 1989 ha influenzato, cambiato, sfidato la creazione scenica in Europa? Si tratterà di vedere in che misura la scossa dell’evento 1989 (di cui non è detto che coincida del tutto con la data 1989) permise alle arti sceniche di anticipare, nel paradossale ‘in più’ di una perdita di parola (che rintracceremo in alcuni lavori teatrali dell’epoca), una profonda trasformazione di cui viviamo oggi gli effetti.
Ark Encounter: The Making of a Creationist Theme Park
2019
“Ark Encounter” is a creationist theme park in Kentucky, a “life-size” replica of Noah’s Ark, which aims to prove the biblical story true by materializing it in stunning detail. Opened in 2016, it ...