Search results for "Forming"
showing 10 items of 1719 documents
Co-creation of IT-value in a cluster of small enterprises
2018
Abstract There is a growing emphasis on digital transformation in research and business practice. The creation of value from IT-investments is a critical factor in digital transformation. Research has documented that the ability to realize IT-value is a very challenging endeavor, especially for small enterprises who because of resource poverty are dependent on external input and cooperation with other companies. There is a general lack of research on the phenomenon of how IT-value is co-created, particularly in small firms. This paper reports from a study of a cluster of performing arts organizations, Blender Collective. They realized that audience data is a key issue, and that they lack th…
TV-theatre: TV Presence in Contemporary Theatre for Children and Young Audiences in Buenos Aires
2009
In Argentina, television shows have created their own theatrical shows, which run for the winter holidays, using the same stories, same characters, and same actors but onstage. Many artists who devote themselves all year long to theatre for children see those “TV-theatre” shows as unfair competition, arguing that such huge productions lack actual artistry and cultural value. This paper aims to examine the characteristics of the TV-theatre, including how much theatre and how much TV languages, codes, and messages it contains, using Pavis´s concept of “intermediality.” If one of theatre for children's greatest goals or outcomes is to create future audiences/theatregoers, and to impart in them…
Liver specific overexpression of platelet-derived growth factor-B accelerates liver cancer development in chemically induced liver carcinogenesis
2010
A genetic basis of hepatocellular carcinoma (HCC) has been well-established and major signaling pathways, such as p53, Wnt-signaling, transforming growth factor-β (TGF-β) and Ras pathways, have been identified to be essential to HCC development. Lately, the family of platelet-derived growth factors (PDGFs) has shifted to the center of interest. We have reported on spontaneously developing liver fibrosis in PDGF-B transgenic mice. Since HCC rarely occurs in healthy liver, but dramatically increases at the cirrhosis stage of which liver fibrosis is a preliminary stage, we investigated liver cancer development in chemically induced liver carcinogenesis in these mice. HCC induction was performe…
Comparative study assessing effects of sonic hedgehog and VEGF in a human co-culture model for bone vascularisation strategies.
2011
The morphogen sonic hedgehog (Shh) seems to mediate adult repair processes in bone regeneration and vascularisation. In this study we investigated the effects of Shh on co-cultures consisting of human primary osteoblasts and outgrowth endothelial cells in terms of angiogenic activation and vessel maturation in comparison to the treatment with the commonly used proangiogenic factor, VEGF. Both, stimulation with VEGF or Shh, leads to an increase in the formation of microvessel-like structures compared to untreated controls. In contrast to VEGF, proangiogenic effects by Shh could already be observed after 24 h of treatment. Nevertheless, after 14 days the angiogenic activity of OEC was compara…
Modification of xenogenic bone substitute materials - effects on the early healing cascadein vitro
2013
Introduction Initial platelet activation with subsequent cytokine release at the defect site plays a crucial role in tissue integration. The aim of this study was to evaluate the influence of topographic and biomimetic collagen modifications of a xenogenic bone substitute material (BSM) on in vitro platelet activation and cytokine release. Material and Methods Three types of xenogenic BSM were used. Two BSM with different levels of granularity (large granule BSM [XBSM/L], small granule BSM [XBSM/S]) and a BSM with collagen (XBSM/C). All three samples were incubated with platelet concentrate of four healthy volunteers at room temperature for 15 min. For all groups, highly thrombogenic collag…
Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?
2016
Endothelial Progenitor Cells (EPCs) are bone marrow derived cells able to differentiate in mature endothelial cells (EC) contributing to the generation of new vessels, connecting to fibronectin, and forming colonies and/or colony forming units. Since circulating EPCs can be actively considered part of endothelial damage in several cardiovascular diseases and autoimmune disorders the possibility to have a measure for endothelium damage should be considered of interest to predict the patient out-come. At the same time the EPCs proliferative and regenerative role could be considered for therapeutic applications. Studies have been performed to elucidate the role of EPCs in Systemic Sclerosis an…
The epistolary of José Gestoso (1852-1917) as a source for the study of the Spanish artistic historiography: Authors index
2019
We want to present the José Gestoso's unpublished epistolary, a rich source of information. It preserves the correspondece received by this person between 1875 and 1917. Gestoso was a researcher of Sevillian Art and History and thanks to his job had relationship with very important people in the XIX century and early XX; this is shown by his correspondence. We considerer this epistolary an important source of information and its diffusion would be useful for the investigations of Art History and Archeology. Presentamos el epistolario inédito del erudito sevillano José Gestoso y Pérez (1852-1917), una riquísima fuente de información que contiene la correspondencia recibida por este personaje…
TIVOLI, HADRIAN'S VILLA: THE PLUTONIUM PROJECT (COMUNE DI TIVOLI, PROVINCIA DI ROMA, REGIONE LAZIO)
2021
The Universities of Pavia and Oxford continued their investigations in Villa Adriana, in the area called Plutonium, traditionally interpreted as a reproduction of the Underworld, and located on one of the highest rises of the complex, in the east part of the Villa. The excavations took place from 1 to 21 July 2019. A team of 12 graduate students and postdoctoral researchers took part in the project, both from Oxford and Pavia Universities (S. Andronio, I. Bossolino, E. Casarotti, A. Dalgkitsi, E. Di Virgilio, V. Jukic Buca, A. Poldi Allai, G. Restaino, T. Runeckles, A. Verde). Dr Gilberto Montali, from the University of Palermo, supervised the architectural survey and documentation of the a…
L’immagine del turco nella Sicilia del Cinquecento
2016
Il contributo individua nella produzione artistica siciliana tra il 1560 e il 1585 alcune opere che contemplano in forme scultoree l’immagine dei “turchi” sconfitti. La “cona” realizzata da Antonino Gagini da Palermo per il duomo di San Giorgio a Ragusa ne offre uno dei primi esempi significativi; sul versante opposto dell’isola, l’esempio più eloquente è rinvenibile nel lato esterno di porta Nuova o porta Austria di Palermo. Le raffigurazioni sono articolate in varianti drammatiche, epiche e, indirettamente, consolatorie, secondo le indicazioni offerte da Vitruvio: l’antico si presta a offrire una spiegazione per eventi tragici e per le condizioni drammatiche del presente. In alcune iconog…