Search results for "Forming"
showing 10 items of 1719 documents
In vitro effects of flunisolide on MMP-9, TIMP-1, fibronectin, TGF-beta1 release and apoptosis in sputum cells freshly isolated from mild to moderate…
2004
Corticosteroids play an important role in inflammation and remodelling of airways and are considered an important therapeutic target in asthma. Inflammation in asthma is characterized by a dysregulation of eosinophil apoptosis and of markers of airways remodelling. We evaluated the ability of flunisolide to inhibit in vitro the release of metalloproteinases-9 (MMP-9), tissue inhibitor metalloproteinases-1 (TIMP-1), transforming growth factor (TGF-beta) and fibronectin by sputum cells (SC) as well as to induce sputum eosinophil apoptosis.The SC, isolated from induced sputum samples of 12 mild-to-moderate asthmatics, were cultured for 24 h in the presence or absence of flunisolide (1, 10 and …
Myofibroblasts Are Evidence of Chronic Tissue Microtrauma at the Endometrial-Myometrial Junctional Zone in Uteri With Adenomyosis.
2017
Background Adenomyosis (AM) uteri exhibit hyperperistalsis. The latter causes a chronic tissue trauma at the endometrial-myometrial junctional zone (EMJZ). Upon tissue trauma, microdehiscences in the myometrium facilitate the translocation of basal endometrial fragments into the myometrium. There, a metaplasia (mediated by transforming growth factor β1 [TGFβ1] and connective tissue growth factor [CTGF]) occurs and AM lesions develop. The abundance of myofibroblasts in a tissue hallmarks metaplasia and points to a tissue microtrauma. Materials and methods To study if myofibroblasts-as an evidence of tissue microtrauma-are more abundant at EMJZ in AM-uteri, a case-control experimental study w…
Association of Inflammation Markers with Impaired Insulin Sensitivity and Coagulative Activation in Obese Healthy Women
2003
Abstract Insulin resistance is associated with a low chronic inflammatory state. In this study we investigated the relationship between impaired insulin sensitivity and selected markers of inflammation and thrombin generation in obese healthy women. We examined 32 healthy obese women (body mass index ≥ 28), with normal insulin sensitivity (NIS, n = 14) or impaired insulin sensitivity (n = 18), and 10 nonobese women (body mass index < 25). Impaired insulin sensitivity patients had significantly higher levels of C-reactive protein (CRP), TGF-β1, plasminogen activator inhibitor-1 (PAI-1), activated factor VII (VIIa), and prothrombin fragment 1 + 2 (F1 + 2) compared with either control s…
TITAFORM - Precision Hot Forming, development of innovative hot-forming processes of aeronautical components in Ti-alloy with low buy/fly ratio: an I…
2012
In the paper the description of the project TITAFORM is provided. The project has been financed on the call "PON Linea 1" of the Italian government and represents an effective example of cooperation between academy and industry. The project is focused on the beta forging and hot stretch forming operations of titanium alloys. �� 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
Tif1γ regulates the TGF-β1 receptor and promotes physiological aging of hematopoietic stem cells.
2014
The hematopoietic system declines with age. Myeloid-biased differentiation and increased incidence of myeloid malignancies feature aging of hematopoietic stem cells (HSCs), but the mechanisms involved remain uncertain. Here, we report that 4-mo-old mice deleted for transcription intermediary factor 1γ (Tif1γ) in HSCs developed an accelerated aging phenotype. To reinforce this result, we also show that Tif1γ is down-regulated in HSCs during aging in 20-mo-old wild-type mice. We established that Tif1γ controls TGF-β1 receptor (Tgfbr1) turnover. Compared with young HSCs, Tif1γ(-/-) and old HSCs are more sensitive to TGF-β signaling. Importantly, we identified two populations of HSCs specifical…
Researches on the Alternative Fuels Which Can Be Used to Motors
2010
The alternative fuels are substances or materials used as fuel, other than the old conventional fuels (oil, natural gases and coals). 
 The paper analyses the most important alternative fuels, such as: bio-diesel, alcohols and hydrogen, presenting at each category the main important characteristics, the advantages and disadvantages presented by them. 
 The methyl-ester which is known as bio-diesel can be used in all motors with ignition by compression, alone or mixed in any proportion with oil, with minor modifications at the injection system. Bio-diesel fuel assures the same motor power as oil does, having even a bigger cetanic number than the usual oil. After tests, it was obser…
On the effectiveness of spif process to re-form end-of-life components as compared to conventional forming approach
2021
Manufacturing processes have a significant impact on global energy consumptions. The recovery of materials and functions for the implementation of the Circular Economy principle needs to be focused on either, by utilizing new techniques or the rethinking of old processes to rework End-of-Life (EoL) components. Previous researches have shown Single Point Incremental Forming (SPIF) process as a good alternative for sheet metal EoL components reuse by their reshaping. In this article, the authors aim to study the effectiveness of the SPIF processes by comparing its reshaping performance with other, more conventional forming processes. An initial Deep Drawing (DD) process was performed to imita…
Stimulated emission and optical properties of pyranyliden fragment containing compounds in PVK matrix
2017
This work has been supported by National Research program “Multifunctional materials and composites, photonics and nanotechnology (IMIS2)”. Financial support provided by Scientific Research Project for Students and Young Researchers No. SJZ2015/12 realised at the Institute of Solid State Physics, University of Latvia is greatly acknowledged.
Contribution de l’analyse de scène auditive à l’analyse de la performance
2017
Disponible sur : http://euromac2017.unistra.fr/wp-content/uploads/2017/05/Ext.-Lalitte-Philippe.pdf. Intervention donnée en Session 13C : Analyser la performance aujourd'hui : enjeux et perspectives; International audience; L’analyse de la performance de musiques savantes écrites des XXe–XXIe siècles pose des problèmes méthodologiques spécifiques à ce répertoire (Lalitte, 2015). Plus que dans un autre répertoire, l’interprète a un rôle particulièrement important pour transmettre à l’auditeur une image auditive (McAdams, 1984) la plus cohérente possible d’œuvres fréquemment qualifiées de perceptivement complexes. Cette constatation est particulièrement cruciale dans la musique polyphonique o…
Generalized power-angle control for grid-forming converters: A structural analysis
2022
Several control schemes have been recently proposed and studied as grid-forming controls for power converters. In all these schemes, the power-angle control loop is the part which defines the fundamental capabilities of the grid-forming control: that control loop governs in fact the inherent synchronization mechanism of the power converter, the power sharing with the other generation sources in the system and the oscillatory characteristics of the converter-based resource. This article introduces a general formulation for the power-angle control characterizing the grid-forming concept for power converters. The generalized power-angle control is based on a polynomial fraction formulation, an…