Search results for "Forming"
showing 10 items of 1719 documents
Sheet Metal Hydroforming Technology - State-of-the-Art
2016
The present paper describes the current status of hydroforming technology in today’s global market that focuses on energy use in respect to increasing requirements especially from the automotive industry with its renaissance after the economic crisis. A vast hydroforming classification and the restrictions and drawbacks for a wider market share are also presented.
A simple experiment to characterize material formability in tube hydroforming
2001
Abstract In tube hydroforming processes an internal fluid pressure is utilized to form the material on a properly shaped die; during the process the material axial movement is favoured by the axial feeding of an active punch. In the paper a simple experiment is presented aimed to investigate the influence of the main process variables on material formability. This equipment has enabled an extensive experimental investigation; furthermore a numerical analysis based on the finite element technique has been performed and a ductile fracture criterion has been implemented to predict the insurgence of bursting defects.
Valorization of alginate for the production of hydrogen via catalytic aqueous phase reforming
2018
Abstract Alginate, a carbohydrate abundant in the outer cell wall of macroalgae, was subjected to catalytic aqueous phase reforming (APR) to produce hydrogen using a 3% Pt/C commercial catalyst. The performance of the process was evaluated according to the conversion of the carbon to gas, the hydrogen yield and the hydrogen selectivity. The catalyst and feed amount, temperature, reaction time, pH and the presence of H2 were modified to understand the dependence of the outcome of the process on these parameters. The presence of the catalyst was fundamental in order to increase the hydrogen yield compared to the uncatalyzed reaction, and it can be reused without activity loss. In addition, it…
Geomorphing effect of sand fences in primary dunes of Gulf of Riga
2022
Finding a the most appropriate solution for the problems caused by coastal eros ion is very important, as erosion prevention and habitat management measures must promote the restoration of the natural balance (order of things before anthropogenic disturbances) and restore the coastal status quo as much as possible [6; 2].Dune fences are a very widespread erosion management tool on developed sandy coastal areas due to ease of installation, inexpensiveness, and generally positive public attitude [1]. Effectiveness and impact of fences have also been studied in many places around the world, however previous studies in Latvia have been very limited and episodic [16].This article shows the obser…
Human CD4+CD25+ T cells derived from the majority of atopic donors are able to suppress TH1 and TH2 cytokine production
2003
Abstract Background: Recently, it has been established that CD4 + CD25 + T cells with regulatory capacity are present in human peripheral blood, inhibiting allogeneic proliferation and cytokine production of preactivated CD4 + CD25 − respond-er T cells. Objective: The aim of this study was to analyze in an allergen-specific setting whether such regulatory CD4 + CD25 + T cells also exist and function normally in atopic individuals, especially concerning the inhibition of T H 2 cytokines. Methods: For this purpose, CD4 + CD25 − or CD4 + CD25 + T cells from donors allergic to grass or birch pollen (mainly with rhinitis) or from healthy nonatopic donors were stimulated in the presence of autolo…
MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer.
2013
It is now largely admitted that a pro-inflammatory environment may curtail anti-tumor immunity and favor cancer initiation and progression. The discovery that small non-coding regulatory RNAs, namely microRNAs (miRNAs), regulate all aspects of cell proliferation, differentiation, and function has shed a new light on regulatory mechanisms linking inflammation and cancer. Thus, miRNAs such as miR-21, miR-125b, miR-155, miR-196, and miR-210 that are critical for the immune response or hypoxia are often overexpressed in cancers and leukemias. Given the high number of their target transcripts, their deregulation may have a number of deleterious consequences, depending on the cellular context. In…
Inhibition of human allergic T-helper type 2 immune responses by induced regulatory T cells requires the combination of interleukin-10-treated dendri…
2006
Summary Background In grass pollen-allergic individuals, T cell anergy can be induced by IL-10-treated dendritic cells (IL-10-DC) resulting in the suppression of T helper type 1 (Th1) as well as Th2 cells. This study was performed to analyse whether such IL-10-DC-treated T cells are able to act as regulatory T cells (Treg) suppressing the function of other T cells in the periphery. As transforming growth factor (TGF)-β is also a potential inducer of Treg, we additionally analysed the inhibitory capacity of TGF-β-treated T cells in this system. Materials and Methods Freshly isolated CD4+ or CD4+CD25− T cells from grass pollen-allergic donors were stimulated with autologous mature monocyte-de…
Reciprocal IFN-gamma and TGF-beta responses regulate the occurrence of mucosal inflammation.
1997
The above new findings concerning the immunological mechanisms governing mucosa, immune responses and oral tolerance in TCR-transgenic mice, as well as those operative in mice with experimental colitis, greatly expand our understanding of the processes that normally control mucosal inflammation and possibly other types of inflammation as well (Fig. 1). They indicate that, in the nondiseased mouse, ingested proteins evoke a Th1-cell (IFN-gamma) response in the mucosal follicles that is quickly counter-regulated by induction of T-cell anergy/deletion, if this Th1-cell response is inhibited (experimentally by anti-IL-12), TGF beta-producing cells appear, and these are capable of active immune …
Play together, think alike: Shared mental models in expert music improvisers
2015
International audience; When musicians improvise together, they tend to agree beforehand on a common structure (e.g. a jazz standard) which helps them coordinate. However, in the particular case of collective free improvisation (CFI), musicians deliberately avoid having such a referent. How, then, can they coordinate? We propose that CFI musicians who have experience playing together come to share higher-level knowledge, which is not piece-specific but rather task-specific: an implicit mental model of what it is to improvise freely. We tested this hypothesis on a group of 19 expert improvisers from the Parisian CFI community, who had various degrees of experience playing with one another. D…
Physico-chemical and mechanical characterization of in-situ forming xyloglucan gels incorporating a growth factor to promote cartilage reconstruction
2016
Abstract The development of growth factors is very promising in the field of tissue regeneration but specifically designed formulations have to be developed in order to enable such new biological entities (NBEs). In particular, the range of therapeutic concentrations is usually very low compared to other active proteins and the confinement in the target site can be of crucial importance. In-situ forming scaffolds are very promising solutions for minimally invasive intervention in cartilage reconstruction and targeting of NBEs. In this work injectable, in-situ forming gels of a temperature responsive partially degalactosylated xyloglucan (Deg-XG) incorporating the growth factor FGF-18 are fo…