Search results for "Fracture"

showing 10 items of 873 documents

The association of calcium intake with osteoporotic vertebral fractures in a large Chinese cohort

2019

The effect of calcium on prevention of osteoporosis and related fracture which are aging issues is unclear. The aim of this study is to explore the association of calcium intake with vertebral fracture. This study enrolled 3,457 participants from China Action on Spine and Hip Status (CASH) study from 2013 and 2017. Dietary calcium intake was collected using validated food frequency questionnaires (FFQ). Vertebral fracture of CT images was defined as the primary outcome. The mean calcium intake of men and women were 522.75mg/day and 507.21mg/day, respectively. 6% reduction in the odds of fracture risk was observed per 100 unit increase of calcium intake from food among females (OR, 0.94; 95%…

MaleFracture riskcalcium intake vertebral fracture QCTChinaAgingmedicine.medical_specialtyPopulationOsteoporosischemistry.chemical_elementCalciumCohort StudiesPrimary outcomeAsian PeopleBone DensityRisk FactorsInternal medicinecalcium intakemedicineHumansProspective StudieseducationDietary calciumvertebral fractureAgedSex Characteristicseducation.field_of_studyBone Density Conservation AgentsFood frequencybusiness.industryCell BiologyMiddle Agedmedicine.diseaseCalcium DietarychemistryCohortOsteoporosisSpinal FracturesCalciumFemalebusinessQCTOsteoporotic FracturesResearch Paper
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Can Clinical and Surgical Parameters Be Combined to Predict How Long It Will Take a Tibia Fracture to Heal? A Prospective Multicentre Observational S…

2018

Background. Healing of tibia fractures occurs over a wide time range of months, with a number of risk factors contributing to prolonged healing. In this prospective, multicentre, observational study, we investigated the capability of FRACTING (tibia FRACTure prediction healING days) score, calculated soon after tibia fracture treatment, to predict healing time.Methods. The study included 363 patients. Information on patient health, fracture morphology, and surgical treatment adopted were combined to calculate the FRACTING score. Fractures were considered healed when the patient was able to fully weight-bear without pain.Results. 319 fractures (88%) healed within 12 months from treatment. Fo…

MaleGenetics and Molecular Biology (all)Immunology and Microbiology (all)lcsh:MedicineTibia fracture multicentre observational studyTibia Fracturefracture; healing; tibiaBiochemistry0302 clinical medicineOsteogenesisMedicineAdolescent; Adult; Female; Fracture Healing; Humans; Male; Middle Aged; Osteogenesis; Prospective Studies; Reproducibility of Results; Tibia; Tibial Fractures; Treatment Outcome; Young AdultProspective Studies030212 general & internal medicineYoung adultProspective cohort studyFracture Healing030222 orthopedicsGeneral MedicineMiddle Agedtibia fractureTreatment OutcomeAdolescent; Adult; Female; Fracture Healing; Humans; Male; Middle Aged; Osteogenesis; Prospective Studies; Reproducibility of Results; Tibia; Tibial Fractures; Treatment Outcome; Young Adult; Biochemistry Genetics and Molecular Biology (all); Immunology and Microbiology (all)Femaletibia fracturetibia FRACTure prediction healINGResearch ArticleAdultmedicine.medical_specialtyArticle SubjectAdolescentBone healingGeneral Biochemistry Genetics and Molecular BiologyNOYoung Adult03 medical and health sciencesHumansIn patientTibiaTime rangetibia FRACTure prediction healINGTibiaGeneral Immunology and Microbiologybusiness.industrylcsh:RReproducibility of ResultsSurgeryTibial FracturesObservational studybusinessBiochemistry Genetics and Molecular Biology (all); Immunology and Microbiology (all)
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Natural history of malignant bone disease in hepatocellular carcinoma: final results of a multicenter bone metastasis survey

2014

BackgroundBone is an uncommon site of metastasis in patients with advanced hepatocellular carcinoma (HCC). Therefore, there are few studies concerning the natural history of bone metastasis in patients with HCC.Patients and methodsData on clinicopathology, survival, skeletal-related events (SREs), and bone-directed therapies for 211 deceased HCC patients with evidence of bone metastasis were statistically analyzed.ResultsThe median age was 70 years; 172 patients were male (81.5%). The median overall survival was 19 months. The median time to the onset of bone metastasis was 13 months (22.2% at HCC diagnosis); 64.9% patients had multiple bone metastases. Spine was the most common site of bon…

MaleGenetics and Molecular Biology (all)medicine.medical_specialtyCarcinoma HepatocellularBone diseaseSettore MED/06 - Oncologia Medicamedicine.medical_treatmentScienceBone NeoplasmsGastroenterology and HepatologyBiochemistryGastroenterologyBone and BonesMetastasisInternal medicineMedicine and Health SciencesmedicineCarcinomaHumansAged; Bone Neoplasms; Bone and Bones; Carcinoma Hepatocellular; Female; Humans; Italy; Liver; Liver Neoplasms; Male; Middle Aged; Quality of Life; Survival Analysis; Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Survival analysisAgedPharmacologyMultidisciplinarybusiness.industryCarcinomaLiver NeoplasmsQRBone metastasisHepatocellularBone fractureMiddle AgedBisphosphonatemedicine.diseaseSurvival Analysiszoledronic acidHepatocellular Carcinomaskeletal-related eventsSurgeryZoledronic acidOncologyItalyLiverAgricultural and Biological Sciences (all)Quality of LifeMedicineFemalebusinessResearch Articlemedicine.drug
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Effects of intensive strength-power training on sense of coherence among 60-85-year-old people with hip fracture: A randomized controlled trial

2012

Background and aims: Older people with disabilities are at increased risk of psychological health decline. There are no earlier studies on the effects of resistance training on sense of coherence (SOC) among older people with a history of hip fracture. The aim of this study is to test the effects of intensive 12-week strength-power training on SOC among older adults after hip fracture. Methods: A clinical sample of 60-85-year-old community-dwelling men and women was studied, 0.5. to 7.0 years after hip fracture. Forty-six had no contraindications for participation and were randomized into training (n=24) and control groups (n=22). The training group participated in a 12-week, individually t…

MaleGerontologyAgingmedicine.medical_specialtySense of CoherenceStrength trainingmedicine.medical_treatmentPhysical exerciselaw.invention03 medical and health sciences0302 clinical medicineQuality of lifeRandomized controlled triallawIntervention (counseling)medicineHumans030212 general & internal medicineAgedAged 80 and overHip fractureRehabilitationHip Fracturesbusiness.industryResistance TrainingRecovery of FunctionMiddle Agedmedicine.diseaseTest (assessment)Physical therapyFemalePower PsychologicalGeriatrics and Gerontologybusiness030217 neurology & neurosurgery
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Predictors of short- and long-term mortality in males and females with hip fracture - A prospective observational cohort study

2013

Background: Hip fracture is associated with increased mortality. Our aim was to study potential risk factors, including osteoporosis, associated with short- and long-term mortality in a prospectively recruited cohort of fragility hip fracture patients. Methodology/Principal Findings: Fragility hip fracture patients aged .50 years admitted to a county hospital in Southern Norway in 2004 and 2005 were consecutively identified and invited for assessment. Patients with high energy or pathological fractures, patients with confusion, serious infections or who were non-residents in the catchment area were excluded. As part of a clinical routine, data were collected using questionnaires. Standardiz…

MaleGerontologylcsh:MedicinemedicineHumansProspective StudiesProspective cohort studylcsh:ScienceAgedAged 80 and overHip fractureMultidisciplinaryBone Density Conservation AgentsDiphosphonatesHip Fracturesbusiness.industryMortality ratelcsh:RBone fracturemedicine.diseasePeer reviewOsteoporosisFemaleLong term mortalitylcsh:QAttributionbusinessResearch ArticleCohort study
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Dynamic biomechanical analysis of different olecranon fracture fixation devices--tension band wiring versus two intramedullary nail systems: an in-vi…

2007

Abstract Background. The aim of this study was to develop a test-setup with continuous angle alteration to imitate joint motion for the evaluation of 3 different olecranon fracture fixation devices. Methods. Twenty-one fresh cadaver upper extremities underwent olecranon fracture by the means of transverse osteotomy and received 3 different fixation systems. Group 1: Tension band wiring according to Weber. Group 2: XS-nail with 9 holes, all locked with 2 mm threaded K-wires. Group 3: Olecranon Nailing System with 90 mm length, locked with 2.7 mm screws, a variable angle locking hole for the proximal fragment and a proximal locking end cap. The servo-pneumatical test stand worked with a rotat…

MaleHumeral FracturesMaterials scienceOlecranonElbowBiophysicsBone Nailslaw.inventionIntramedullary rodFixation (surgical)Fracture Fixation InternallawFracture fixationElbow JointmedicineHumansOrthopedics and Sports MedicineDisplacement (orthopedic surgery)AgedOrthodonticsTension band wiringAnatomymedicine.diseaseBiomechanical Phenomenamedicine.anatomical_structureOlecranon fractureFemaleElbow InjuriesClinical biomechanics (Bristol, Avon)
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Bone marrow fat quantification of osteoporotic vertebral compression fractures: comparison of multi-voxel proton MR spectroscopy and chemical-shift g…

2011

Background Only a few studies have used in/opposed phase method for a quantitative evaluation of fat fraction in the spine. Purpose To compare multivoxel proton MR spectroscopy and chemical-shift gradient-echo MR imaging for bone marrow fat quantification in vertebral compression fractures (VCF). Material and Methods Vertebral marrow fat quantification in fifteen patients was measured at 3.0-T. Multi-voxel proton spectroscopy (MRS) and in/opposed-phase MR imaging using a fat map build with a triple-echo gradient-echo sequence was used. All the patients had benign vertebral collapse. Bone marrow fat content was evaluated by both techniques in compressed (acute or chronic) and in non-compress…

MaleIn vivo magnetic resonance spectroscopyMagnetic Resonance Spectroscopy[SDV]Life Sciences [q-bio]Fat quantificationcomputer.software_genreMESH: Magnetic Resonance Imaging030218 nuclear medicine & medical imagingMESH: Aged 80 and over0302 clinical medicineBone MarrowVoxelFractures CompressionMESH: Fractures CompressionAged 80 and overMESH: AgedMESH: Middle Aged[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingRadiological and Ultrasound TechnologyGeneral MedicineMiddle AgedCompression (physics)LipidsMagnetic Resonance Imagingmedicine.anatomical_structureAcute DiseaseSpinal FracturesMESH: Acute DiseaseFemaleMESH: Bone MarrowMESH: OsteoporosisAdultMESH: Spinal Fractures03 medical and health sciences[INFO.INFO-IM]Computer Science [cs]/Medical ImagingmedicineHumansRadiology Nuclear Medicine and imagingAgedMESH: HumansMESH: Magnetic Resonance Spectroscopybusiness.industryMESH: Chronic DiseaseVertebral compression fractureMESH: Adultmedicine.diseaseMESH: LipidsMr imagingMESH: MaleProton mr spectroscopyChronic DiseaseOsteoporosisBone marrowbusinessNuclear medicineMESH: Femalecomputer030217 neurology & neurosurgeryActa Radiologica
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Longitudinal associations of high‐volume and vigorous‐intensity exercise with hip fracture risk in men

2022

Maintenance of vigorous exercise habits from young to old age is considered protective against hip fractures, but data on fracture risk in lifelong vigorous exercisers are lacking. This longitudinal cohort study examined the hazard of hip fractures in 1844 male former athletes and 1216 population controls and in relation to exercise volume and intensity in later years. Incident hip fractures after age 50 years were identified from hospital discharge register from 1972 to 2015. Exercise and covariate information was obtained from questionnaires administered in 1985, 1995, 2001, and 2008. Analyses were conducted using extended proportional hazards regression model for time-dependent exposures…

MaleLONG-TERMEndocrinology Diabetes and MetabolismosteoporoosiPARTICIPATIONEXERCISEpitkittäistutkimusOSTEOPOROSISDISEASEAGINGTIME PHYSICAL-ACTIVITYRisk FactorsHumansQUALITYlongitudinal studiesOrthopedics and Sports MedicineluunmurtumatAgedProportional Hazards ModelsREGISTERexerciseHip FractureskuntoliikuntaagingLONGITUDINAL STUDIESMiddle AgedosteoporosislonkkaFRACTURE PREVENTIONLIFESIZEikääntyminenBALANCE3121 General medicine internal medicine and other clinical medicinefracture preventionmiehetBONE-MINERAL DENSITYikääntyneet
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Low-dose vitamin D supplementation and incident frailty in older people: An eight year longitudinal study.

2018

Hypovitaminosis D is associated with frailty, but if vitamin D supplementation may prevent the onset of frailty is poorly known. Therefore, we aimed to investigate whether vitamin D supplementation is associated with a lower risk of frailty. In this longitudinal study, 4,421 individuals at high risk or having knee osteoarthritis free from frailty at baseline (mean age: 61.3, females = 58.0%) were followed for 8 years. Details regarding vitamin D supplementation were captured by asking whether the participant took vitamin D during the previous year, at least once per month. Frailty was defined using the Study of Osteoporotic Fracture (SOF) index as the presence of at least two of the followi…

MaleLongitudinal studyAging*Osteoarthritis initiativeBiochemistry0302 clinical medicineEndocrinologyOutcome Assessment Health CareMedicine030212 general & internal medicineOlder adult*FrailtyVitamin D*Older adultsFrailtyIncidence (epidemiology)Osteoarthritis initiativeConfoundingHazard ratioVitaminsMiddle AgedOlder adultsFemale*Vitamin Dmedicine.medical_specialty030209 endocrinology & metabolismFrailty; Older adults; Osteoarthritis initiative; Vitamin DLower riskArticle03 medical and health sciencesInternal medicineWeight LossGeneticsVitamin D and neurologyHumansMobility LimitationPropensity ScoreMolecular BiologyAgedProportional Hazards Modelsbusiness.industryCell BiologyVitamin D DeficiencyConfidence intervalUnited StatesPropensity score matchingDietary SupplementsPhysical therapybusinessOsteoporotic FracturesFollow-Up StudiesExperimental gerontology
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Heterogeneity in Risk Factors for Cognitive Impairment, No Dementia: Population-Based Longitudinal Study From the Kungsholmen Project

2006

OBJECTIVES: The objectives of this study were to investigate the relation of vascular, neuropsychiatric, social, and frailty-related factors with "Cognitive impairment, no dementia" (CIND) and to verify their effect independently of future progression to Alzheimer disease (AD). METHODS: Seven hundred eighteen subjects aged 75+ years who attended baseline, 3- and 6-year follow-up examinations of the Kungsholmen Project, a Swedish prospective cohort study, were studied. CIND was defined according to the performance on the Mini-Mental State Examination. Potential risk factors were collected at baseline and clustered according to four research hypotheses (frailty, vascular, neuropsychiatric, an…

MaleLongitudinal studyPsychosisPopulationAlzheimer DiseaseRisk FactorsActivities of Daily Livingmental disordersmedicineHumansDementiaeducationProspective cohort studyAgedProportional Hazards ModelsAged 80 and overSwedenPolypharmacyeducation.field_of_studyHip fractureHip FracturesMild cognitive impairment Alzheimer disease hip fracture polypharmacy psychosismedicine.diseasePsychiatry and Mental healthPsychotic DisordersDisease ProgressionPolypharmacyFemaleSettore MED/26 - NeurologiaGeriatrics and GerontologyAlzheimer's diseaseCognition DisordersPsychologyFollow-Up StudiesClinical psychologyThe American Journal of Geriatric Psychiatry
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