Search results for "Fractures"

showing 10 items of 379 documents

Serum Albumin and Future Risk of Hip, Humeral, and Wrist Fractures in Caucasian Men:New Findings from a Prospective Cohort Study

2018

<b><i>Objective:</i></b> Low serum albumin concentration is associated with poor health outcomes, but its relationship with the risk of fractures has not been reliably quantified. We aimed to assess the prospective association of serum albumin with the risk of fractures in a general population. <b><i>Subjects and Methods:</i></b> Baseline serum albumin concentrations were measured in 2,245 men aged 42–61 years in the Kuopio Is­chemic Heart Disease study. Hazard ratios (HRs) (95% confidence intervals) were calculated for incident fractures. <b><i>Results:</i></b> A total of 121 fractures (hip, humeral, or wrist) were rec…

AdultMale0301 basic medicinemedicine.medical_specialty020205 medical informaticsPopulationSerum albuminSerum albuminComorbidity02 engineering and technologyWhite PeopleCohort StudiesFractures Bone03 medical and health sciencesRisk FactorsInternal medicine0202 electrical engineering electronic engineering information engineeringmedicineHumansProspective StudieseducationProspective cohort studyFinlandSerum AlbuminOriginal Papereducation.field_of_studybiologyHip Fracturesbusiness.industryHazard ratioArea under the curveGeneral MedicineMiddle AgedWrist InjuriesConfidence intervalFractureQuartileCentre for Surgical Researchbiology.protein030101 anatomy & morphologybusiness/dk/atira/pure/core/keywords/centre_for_surgical_researchBody mass index
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Etiology, distribution, treatment modalities and complications of maxillofacial fractures

2013

Purpose: This study evaluated the trends and factors associated with maxillofacial fractures treated from 1997 to 2007 in the Oral and Maxillofacial Surgery Department of the Clermont-Ferrand University Hospital. Material and Methods: This study included 364 patients of which 82% were men and 45%, 20-29-years old. The etiology, anatomical distribution, treatment modality and complications of maxillofacial fractures were examined. Results: Overall, interpersonal violence, traffic accidents and falls were the most common mechanisms of injury. There was a decreasing trend in traffic accidents and increasing one in falls as a cause of fracture over the 11-years period of this study. Young male …

AdultMaleAdolescentDentistryPoison controlOdontologíaFacial BonesMaxillary FracturesOccupational safety and healthFractures BoneYoung AdultInjury preventionHumansMedicineYoung adultGeneral DentistryAgedRetrospective StudiesAged 80 and overOsteosynthesisbusiness.industryResearchRetrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASOral and maxillofacial surgeryEtiologyFemaleSurgeryOral Surgerybusiness
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Mandibular trauma treatment: a comparison of two protocols

2014

Objectives: The aim of this study was to evaluate the treatment of mandibular fractures treated in two European centre in 10 years. Study Design: This study is based on 2 systematic computer-assisted databases that have continuously recorded patients hospitalized with maxillofacial fractures in two centers in Turin, Italy and in Amsterdam, the Netherlands for ten years. Only patients who were admitted for mandibular fractures were considered for this study. Results: Between 2001 and 2010, a total of 752 patients were admitted at Turin hospital with a total of 1167 mandibular fractures not associated with further maxillofacial fractures, whereas 245 patients were admitted at Amsterdam hospit…

AdultMaleAdolescentMandibular fractureDentistryOdontologíaYoung AdultClinical Protocolsstomatognathic systemMandibular FracturesmedicineHumansChildGeneral DentistryAgedAged 80 and overbusiness.industryResearchTrauma treatmentMandibleTreatment optionsMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludOtorhinolaryngologyMulticenter studyChild PreschoolUNESCO::CIENCIAS MÉDICASFemaleSurgeryOral SurgerybusinessMedicina Oral Patologia Oral y Cirurgia Bucal
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Hydroxylation of collagen type I: evidence that both lysyl and prolyl residues are overhydroxylated in osteogenesis imperfecta

1995

The composition of the collagens secreted into the media of fibroblast cultures of 39 patients with osteogenesis imperfecta (OI) was the same in controls and OI cultures. An abnormal migration pattern of collagens upon SDS-PAGE was evident in one third of the cultures investigated. Lysyl and prolyl hydroxylation of HPLC-purified alpha 1(I) chains was elevated in about 60% of cultures. The degree of hydroxylation was highest in the lethal forms. The extent of lysyl and prolyl hydroxylation showed a strong correlation (r = 0.74, P < 0.001). While high levels of hydroxylation are frequently observed in OI patients, a direct correlation between lysyl or prolyl hydroxylation and fracture rate or…

AdultMaleAdolescentProlineClinical BiochemistryAlpha (ethology)Fibroblast culturesHydroxylationHydroxylysineBiochemistryHydroxylationFractures Bonechemistry.chemical_compoundHydroxyprolinePregnancymedicineHumansChildCells CulturedCollagen typeGrowth retardationLysineInfantGeneral MedicineFibroblastsMiddle AgedOsteogenesis Imperfectamedicine.diseaseMolecular biologyBody HeightHydroxyprolineHydroxylysinePhenotypechemistryBiochemistryOsteogenesis imperfectaChild PreschoolFemaleCollagenEuropean Journal of Clinical Investigation
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The massacre mass grave of Schöneck-Kilianstädten reveals new insights into collective violence in Early Neolithic Central Europe

2015

Conflict and warfare are central but also disputed themes in discussions about the European Neolithic. Although a few recent population studies provide broad overviews, only a very limited number of currently known key sites provide precise insights into moments of extreme and mass violence and their impact on Neolithic societies. The massacre sites of Talheim, Germany, and Asparn/Schletz, Austria, have long been the focal points around which hypotheses concerning a final lethal crisis of the first Central European farmers of the Early Neolithic Linearbandkeramik Culture (LBK) have concentrated. With the recently examined LBK mass grave site of Schöneck-Kilianstädten, Germany, we present ne…

AdultMaleAdolescentTorturePopulationMass violenceViolenceWarfare and Armed ConflictsFractures BoneYoung AdultGermanyHumansCemeteriesChildeducationeducation.field_of_studyMultidisciplinaryGeographyFossilsRadiometric DatingSkullInfantAgricultureBiological SciencesArchaeologyEuropeGeographyArchaeologyAustriaChild PreschoolEthnologyFemaleProceedings of the National Academy of Sciences
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Changing pattern and etiology of maxillofacial fractures during the civil uprising in Western Libya

2018

Background The purpose of the present study was to evaluate changing pattern in characteristics of maxillofacial fractures and concomitant injuries in Western Libya During revolution and to assess the association between mechanism of injury and fracture patterns. Material and Methods A retrospective review of medical records and radiographs of 187 patients treated for maxillofacial fractures from January 2010 to December 2012 was performed, there were 326 fractures in 187 patients. Results The male: female ratio was 6:1. Most fractures occurred in patients aged 11 to 40 years, and few injuries occurred in patients aged > 50 years. Most fractures occurred from motor vehicle accidents, and ot…

AdultMaleAdolescentmedicine.medical_treatmentDentistryCivil DisordersLibyaCondyleFacial BonesMaxillary Fractures03 medical and health sciencesYoung Adult0302 clinical medicineMandibular FracturesmedicineHumans030212 general & internal medicineYoung adultChildGeneral DentistryReduction (orthopedic surgery)AgedRetrospective StudiesAged 80 and overSkull Fracturesbusiness.industryMedical recordResearchMandibleInfantRetrospective cohort study030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]OtorhinolaryngologyMaxillaChild PreschoolUNESCO::CIENCIAS MÉDICASEtiologySurgeryFemaleMaxillofacial InjuriesOral SurgerybusinessMedicina Oral, Patología Oral y Cirugía Bucal
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Fatal cranial injury in an individual from Messina (Sicily) during the times of the Roman Empire.

2013

Forensic and archaeological examinations of human skeletons can provide us with evidence of violence. In this paper, we present the patterns of two cranial lesions found on an adult male (T173) buried in a grave in the necropolis ‘Isolato 96’, Messina, Sicily, dating back to the Roman Empire (1st century BC - 1st century AD). The skull reveals two perimortem traumatic lesions, one produced by a sharp object on the right parietal bone and the other one on the left parietal bone, presumably the result of a fall. The interpretation of fracture patterns found in this cranium are an illustration of how forensic approaches can be applied with great benefit to archaeological specimens. 2013 Elsevi…

AdultMaleAdult malePoison controlSettore BIO/08 - AntropologiaRoman WorldPathology and Forensic MedicineLeft parietal boneParietal BonemedicineHead Injuries PenetratingHumansRight parietal boneHistory AncientSkull Fracturesbusiness.industryForensic anthropologyGeneral MedicineAnthropology Cranial trauma ForensicArchaeologyCranial traumaRoman EmpireSkullmedicine.anatomical_structureItalyForensic AnthropologybusinessLawJournal of forensic and legal medicine
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Treatment of malar and midfacial fractures with osteoconductive forged unsintered hydroxyapatite and poly-L-lactide composite internal fixation devic…

2013

Purpose To evaluate the internal fixation of malar and midfacial fractures, long-term results, and biocompatibility of osteoconductive internal fixation devices composed of a forged composite of unsintered hydroxyapatite and poly-L-lactide (F-u-HA/PLLA). Materials and Methods From January 2006 to June 2010, 29 patients (24 males and 5 females; age 33 ± 15 years) were included in the present prospective study. The fracture type was malar in 24 patients, midfacial in 5, isolated orbital floor blowout in 2, and frontal sinus, cranial base in 2 patients. The fractures were fixed with internal fixation devices; these were plates and screws composed of F-u-HA/PLLA. The 24 patients with malar frac…

AdultMaleBiocompatibilityAdolescentRadiographymedicine.medical_treatmentPolyestersDentistryFractures BoneFracture fixationmedicineInternal fixationHumansProspective StudiesBone growthFrontal sinusZygomabusiness.industryUltrasoundMiddle Agedmedicine.diseaseInternal Fixatorsmedicine.anatomical_structureDurapatiteOtorhinolaryngologyFaceSurgeryFemaleOral SurgeryForeign bodybusinessTomography X-Ray ComputedJournal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
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TNF-α in CRPS and 'normal' trauma--significant differences between tissue and serum.

2011

Posttraumatic TNF-alpha signaling may be one of the factors responsible for pain and hyperalgesia in complex regional pain syndromes (CRPS). In order to further specify the role of TNF-alpha we investigated tissue (skin) and serum concentrations in three different patient groups: patients with osteoarthritis and planned surgery, with acute traumatic upper limb bone fracture waiting for surgery, and with CRPS I. Thirty patients (10 in each group) were recruited. Mean CRPS duration was 36.1 ± 8.1 weeks (range 8- 90 weeks). Skin punch biopsies were taken at the beginning of the surgery in osteoarthritis and fracture patients and from the affected side in CRPS patients. Blood samples were taken…

AdultMaleBone pathologyEnzyme-Linked Immunosorbent AssayPilot ProjectsOsteoarthritisFractures BoneOsteoarthritismedicineHumansAgedSkinAged 80 and overmedicine.diagnostic_testbusiness.industryTumor Necrosis Factor-alphaBone fractureMiddle Agedmedicine.diseaseUp-RegulationAnesthesiology and Pain Medicinemedicine.anatomical_structureComplex regional pain syndromeNeurologyAnesthesiaSkin biopsyHyperalgesiaAcute DiseaseUpper limbWounds and InjuriesTumor necrosis factor alphaFemaleNeurology (clinical)medicine.symptombusinessComplex Regional Pain SyndromesPainReferences
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Outcome of COVID19 in Patients With Osteogenesis Imperfecta: A Retrospective Multicenter Study in Saudi Arabia

2022

BackgroundAlthough genetic diseases are rare, children with such conditions who get infected with COVID-19 tend to have a severe illness requiring hospitalization. Osteogenesis imperfecta (OI) is a rare genetic disorder of collagen resulting in fractures and skeletal deformities. Kyphoscoliosis, restrictive lung disease, and pneumonia worsen the prognosis of patients with OI. The use of bisphosphonate improves bone mineral density (BMD) and reduces fractures in OI. There is no literature describing the impact of COVID-19 in patients with OI.MethodologyA retrospective multi-center study was performed in three hospitals in Jeddah and Riyadh, Saudi Arabia, from March 1st, 2020, until August 31…

AdultMaleCOVID - 19bisphosphonateAdolescentEndocrinology Diabetes and MetabolismSaudi Arabiaosteogenesis imperfectaDiseases of the endocrine glands. Clinical endocrinologyFractures BoneYoung AdultEndocrinologyBone DensityHypothesis and TheoryHumansChildRetrospective StudiesDiphosphonatesSARS-CoV-2COVID-19PrognosisRC648-665HospitalizationfractureoutcomeFemaleFollow-Up StudiesFrontiers in Endocrinology
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