Search results for "Function"
showing 10 items of 14432 documents
Contribution to the research of microbial and RedOx bio-indicators for the early characterisation of wood diseases in grapevines
2022
Grapevine trunk diseases, linked to pathogenic fungi whose mechanism of action is still poorly characterised, are responsible for grapevine decline in vineyards throughout the world, causing significant losses in productivity and yield in the wine sector. Given the current lack of effective solutions to stop the establishment of the disease and the development of symptoms, which are irreversible but often late in relation to the pathogenic infection, early diagnosis of these diseases is essential. Considering the grapevine holobiont, i.e. the grapevine and the microbiota interacting with, we hypothesise that early bio-indicators of diseases would make it possible to identify a disturbance i…
Different Medicago truncatula genotypes, expressing different phenotypes, modulate microbial functional genes in the rhizosphere
2022
Plants host in their rhizosphere a remarkable diversity of microorganisms that in return promote plant growth and health. Thus, the plant microbiota emerges as a novel component that expand the capacity of plants to adapt to the environment, and thus pave the way for future breeding approaches.It is widely known that different plant species harbor different microbiota, but very few studies showed an impact of the plant genotypes on the microbiota. These contrasting results may depend on the choice of the tested genotypes.We formulate the hypothesis that only those plant genotypes showing high genetic diversity and expressing different phenotypes harbor different rhizosphere microbiota and a…
Identification of functional markers of mycorrhiza efficiency in vineyard
2021
Arbuscular mycorrhizal fungi form a mutualistic symbiotic association with more than 80% ofland plants, including vines. Advantages of this mutualistic symbiosis are countless. Rootcolonisation by mycorrhizal fungi is mainly evaluated through staining and microscopicobservation. However those technics do not allow to differentiate different mycorrhizal fungi.In order to overcome those limits other tools, like antibodies, isoenzymes and molecular biologytechnics, can be used. Nevertheless, all of these methods “only” allow detection of the presenceof mycorrhizal fungi, whereas no information is provided on the proper mycorrhizal symbiosisfunctioning, and therefore on the benefits provided to…
Agricultural advances
2013
CT3 ; Département E.A. ; SOFIA; Agricultural advances
Identification and diagnosis of patients with familial chylomicronaemia syndrome (FCS): Expert panel recommendations and proposal of an "FCS score".
2018
Familial chylomicronaemia syndrome (FCS) is a rare, inherited disorder characterised by impaired clearance of triglyceride (TG)-rich lipoproteins from plasma, leading to severe hypertriglyceridaemia (HTG) and a markedly increased risk of acute pancreatitis. It is due to the lack of lipoprotein lipase (LPL) function, resulting from recessive loss of function mutations in the genes coding LPL or its modulators. A large overlap in the phenotype between FCS and multifactorial chylomicronaemia syndrome (MCS) contributes to the inconsistency in how patients are diagnosed and managed worldwide, whereas the incidence of acute hypertriglyceridaemic pancreatitis is more frequent in FCS. A panel of Eu…
Pentamidine rescues contractility and rhythmicity in a Drosophila model of myotonic dystrophy heart dysfunction
2015
Up to 80% of individuals with myotonic dystrophy type 1 (DM1) will develop cardiac abnormalities at some point during the progression of their disease, the most common of which is heart blockage of varying degrees. Such blockage is characterized by conduction defects and supraventricular and ventricular tachycardia, and carries a high risk of sudden cardiac death. Despite its importance, very few animal model studies have focused on the heart dysfunction in DM1. Here, we describe the characterization of the heart phenotype in a Drosophila model expressing pure expanded CUG repeats under the control of the cardiomyocyte-specific driver GMH5-Gal4. Morphologically, expression of 250 CUG repeat…
Protein S-nitrosylation: specificity and identification strategies in plants
2015
SPE Pôle IPM UB; International audience; The role of nitric oxide (NO) as a major regulator of plant physiological functions has become increasingly evident. To further improve our understanding of its role, within the last few years plant biologists have begun to embrace the exciting opportunity of investigating protein S-nitrosylation, a major reversible NO-dependent post-translational modification (PTM) targeting specific Cys residues and widely studied in animals. Thanks to the development of dedicated proteomic approaches, in particular the use of the biotin switch technique (BST) combined with mass spectrometry, hundreds of plant protein candidates for S-nitrosylation have been identi…
Observations of land use transformations during the Neolithic using exploratory spatial data analysis: contributions and limitations
2010
International audience; The settlement pattern analysis in archaeology implies some methodological questions. In this paper, we question some issues about the use of geostatistical methods for the observation of land use transformations during the Neolithic. We have developed two examples in Burgundy (France): the first one on a regional scale and the second one on a micro-regional scale. Using different ESDA approaches (Ripley’K function, Nearest Neighbour Distance, Kernel Density Estimation), we would like to underline what the methodological and archaeological contributions and their limits are. Both experiences point out that the results obtained depend not only on the analytical scale,…
ToToPI (Topographie de Tours Pré-Industriel), a GIS for understanding urban dynamics based on the OH_FET model (Social Use, Space and Time)
2009
http://proceedings.caaconference.org/files/2009/41_Rodier_et_al_CAA2009.pdf; International audience; ToToPI, for Topography of Tours Pre-Industrial, is a GIS for studying of the city of Tours (France) in large time span. The concepts for understanding the urban dynamic is based on considering the town as a set of complex objects, taking a systemic approach. The town system used to study the urban fabric over large time spans is composed of three sub-systems relating to historical objects from the level of the excavation to that of the former urban space: function (social use), space (location, surface area and morphology) and time (dating, duration and chronology). The historical object is …
Showing the Invisible: The Economic Cycle of Stone Tools
2023
This contribution takes place in a broader theme, that of “the invisible economy of recyclable materials”. It aims to illustrate the phenomena of recovery of materials from lithic tools and their consequences. The classification of tools by material, although classic, is not relevant from a technical point of view. The material of a tool, in particular its mechanical properties, is to be taken into consideration in its technical analysis, but it cannot constitute a determining criterion in a classification system. Function should come first, as most functional categories use multiple materials. The most striking example, if one can say so, is that of the striking supports, where one finds, …