Search results for "Function"
showing 10 items of 14432 documents
Harmonic balance analysis of pull-in range and oscillatory behavior of third-order type 2 analog PLLs
2020
The most important design parameters of each phase-locked loop (PLL) are the local and global stability properties, and the pull-in range. To extend the pull-in range, engineers often use type 2 PLLs. However, the engineering design relies on approximations which prevent a full exploitation of the benefits of type 2 PLLs. Using an exact mathematical model and relying on a rigorous mathematical thinking this problem is revisited here and the stability and pull-in properties of the third-order type 2 analog PLLs are determined. Both the local and global stability conditions are derived. As a new idea, the harmonic balance method is used to derive the global stability conditions. That approach…
Bis-organosilane applications and synthesis
2017
Tutkielman kirjallisuusosuudessa perehdytään organofunktionaalisiin silaaneihin. Näitä yhdisteitä käytetään kytkentäaineina komposiittien valmistuksessa sekä monessa muussa sovelluksessa, kuten hydrofobisten ja hydrofiilisten pintojen muodostamiseen, kuivausaineina, ulkoisena elektroniluovuttajana polymeroinnissa, sekä kosteuskovettuvien silaanimodifioitujenpolymeeriliimojen (SMP) kovettumisreaktiossa. Silaanien kosteuskovettuminen johtuu pii-atomiin (Si) sitoutuneiden ryhmien hydrolysoitumisesta kosteuden vaikutuksesta, jolloin syntyy silanoli-ryhmiä (Si-OH), jotka voivat edelleen kondensoitua keskenään muodostaen siloksaanisidoksia (Si-O-Si) tai sidoksia pintojen hydroksyyliryhmien kanssa…
An interactive surrogate-based method for computationally expensive multiobjective optimisation
2019
Many disciplines involve computationally expensive multiobjective optimisation problems. Surrogate-based methods are commonly used in the literature to alleviate the computational cost. In this paper, we develop an interactive surrogate-based method called SURROGATE-ASF to solve computationally expensive multiobjective optimisation problems. This method employs preference information of a decision-maker. Numerical results demonstrate that SURROGATE-ASF efficiently provides preferred solutions for a decision-maker. It can handle different types of problems involving for example multimodal objective functions and nonconvex and/or disconnected Pareto frontiers. peerReviewed
Validation of the ISTH/SSC bleeding assessment tool for inherited platelet disorders: A communication from the Platelet Physiology SSC
2020
Background: Careful assessment of bleeding history is the first step in the evaluation of patients with mild/moderate bleeding disorders, and the use of a bleeding assessment tool (BAT) is strongly encouraged. Although a few studies have assessed the utility of the ISTH-BAT in patients with inherited platelet function disorders (IPFD) none of them was sufficiently large to draw conclusions and/or included appropriate control groups. Objectives: The aim of the present study was to test the utility of the ISTH-BAT in a large cohort of patients with a well-defined diagnosis of inherited platelets disorder in comparison with two parallel cohorts, one of patients with type-1 von Willebrand disea…
Funkcja wizerunkowa nazw blogów
2017
Przedmiotem artykułu są nazwy blogów internetowych, które jako komunikat pierwszego kontaktu z odbiorcą pełnią funkcję wizerunkową i promocyjną. Nazwy budują tożsamość i wizerunek marki, nadają jej znaczenie i przesłanie, podkreślają indywidualność i unikatowość.
Is Oxidative Stress the Link Between Cerebral Small Vessel Disease, Sleep Disruption, and Oligodendrocyte Dysfunction in the Onset of Alzheimer’s Dis…
2021
Oxidative stress is an early occurrence in the development of Alzheimer’s disease (AD) and one of its proposed etiologic hypotheses. There is sufficient experimental evidence supporting the theory that impaired antioxidant enzymatic activity and increased formation of reactive oxygen species (ROS) take place in this disease. However, the antioxidant treatments fail to stop its advancement. Its multifactorial condition and the diverse toxicological cascades that can be initiated by ROS could possibly explain this failure. Recently, it has been suggested that cerebral small vessel disease (CSVD) contributes to the onset of AD. Oxidative stress is a central hallmark of CSVD and is depicted as …
Body image during sexual activity in the population of Polish adult women
2020
Introduction. Recently it has been shown that body image during sexual activities is a better predictor of the diversity of sexual experience than body image as a psychological trait. To measure contextual body image (as a state) the Body Exposure During Sexual Activity Questionnaire (BESAQ) was developed. Material and methods. 845 women aged 18-55 years were included in the study. The original model was first translated into Polish and consulted to create the version to be further validated. The original model was tested using confirmatory factor analysis (CFA). The population was divided in two equal groups – group 1 was used for exploratory factor analysis. Discriminant and convergent va…
Sexual behaviors and function during menopausal transition—does menopausal hormonal therapy play a role?
2020
Objectives: The menopausal transition is a biological adaptation to the variety of life changes (body, comorbidities, relationship), but that biology is not an “end all” in the context of sexual function and overall sexual health. The aim of this study is to evaluate determinants altering the risk of female sexual dysfunction (FSD) and other sexual problems and to establish whether menopausal hormonal therapy (MHT) decreases that risk and modifies sexual behaviors. Methods: A cross-sectional observational study was conducted in 210 women between the ages of 45 and 55. Two groups were identified: MHT users (n = 107) and controls—MHT non-users (n = 103). Diagnostic and Statistical Manual of M…
Palladium-catalyzed heteroaryl thioethers synthesis overcoming palladium dithiolate resting states inertness: Practical road to sulfones and NH-sulfo…
2018
International audience; We provide efficient synthetic access to heteroaryl sulfones in two-steps using a simple palladium-1,1'-bis [(diphenyl)phosphanyl]ferrocene catalyst to form in high yields variously functionalized heteroaromatic thioethers. Pyridinyl-containing substrates can be subsequently selectively oxidized into sulfones and NH-sulfoximines by using very mild oxidation conditions with a high functional group tolerance. In the palladium catalyzed C-S coupling of heteroaromatic thiols, reactivity limitation is attached with electron-deficient thiols. We show that this limitation can be resolved by the successful use of 2-bromoheteroarenes in the C-S coupling. We established herein…
Childhood adversity, bonding and family functioning – is there a specific association with borderline personality disorder in adolescents?
2014
Objective: Despite growing evidence on risk-factors of borderline personality disorder (BPD) in adults, there is a paucity of research on such specific characteristics of BPD in youth. Furthermore, studies on adolescence BPD in clinical setting are still rare. This study aimed to investigate adverse childhood experiences, parental bonding and family functioning in a sample of female adolescent inpatients with BPD, and to compare them with a clinical control group with mixed psychiatric diagnoses. Method: A consecutive sample of 91 female adolescents inpatients (ages 12-18 years) was recruited within a psychiatric university hospital. BPD was assessed using the Structured Clinical Interview …