Search results for "Functions"
showing 10 items of 1066 documents
Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma
2014
Diffuse large B cell lymphoma (DLBCL) is the most common lymphoma subtype and is clinically aggressive. To identify genetic susceptibility loci for DLBCL, we conducted a meta-analysis of 3 new genome-wide association studies (GWAS) and 1 previous scan, totaling 3,857 cases and 7,666 controls of European ancestry, with additional genotyping of 9 promising SNPs in 1,359 cases and 4,557 controls. In our multi-stage analysis, five independent SNPs in four loci achieved genome-wide significance marked by rs116446171 at 6p25.3 (EXOC2; P = 2.33 × 10 '21), rs2523607 at 6p21.33 (HLA-B; P = 2.40 × 10 '10), rs79480871 at 2p23.3 (NCOA1; P = 4.23 × 10 '8) and two independent SNPs, rs13255292 and rs47336…
Species cohesion despite extreme inbreeding in a social spider.
2011
Colonial social spiders experience extreme inbreeding and highly restricted gene flow between colonies; processes that question the genetic cohesion of geographically separated populations and which could imply multiple origins from predecessors with limited gene flow. We analysed species cohesion and the potential for long-distance dispersal in the social spider Stegodyphus dumicola by studying colony structure in eastern South Africa and the cohesion between this population and Namibian populations previously published. Data from both areas were (re)analysed for historic demographic parameters. Eastern South African S. dumicola were closely related to an east Namibian lineage, showing coh…
Molecular phylogeny of the Notostraca
2012
Abstract We used a combined analysis of one nuclear (28S rDNA) and three mitochondrial markers (COI, 12S rDNA, 16S rDNA) to infer the molecular phylogeny of the Notostraca, represented by samples from the six continents that are inhabited by this group of branchiopod crustaceans. Our results confirm the monophyly of both extant notostracan genera Triops and Lepidurus with good support in model based and maximum parsimony analyses. We used branchiopod fossils as a calibration to infer divergence times among notostracan lineages and accounted for rate heterogeneity among lineages by applying relaxed-clock models. Our divergence date estimates indicate an initial diversification into the gener…
Alexander Chak’s Correspondence – historical and artistic value of the Latvian cultural heritage
2013
Evaluating and grouping the literature historical relics, including the correspondences by letters between famous people, for a ground (base) we could take categories which demonstrate the qualities which have elements from the material world in an anent with a human. The cultural historian Fridrich Waidacher by researching the interconnection and selective values between material and spiritual world classified the evidences of material world in several chapters which are not strictly caged in permanent schemes (patterns). The division was made by taking F. Waidacher conception as a base and researching the correspondence by letters of Latvian poets and cultural workers: The potential value…
The Influence of Local Culture on Students' Educational Outcomes
2013
All adolescents are closely connected with their living environment, which influences their lives and learning in many ways. For example, individuals’ mental functions develop in interaction within different social, historical, cultural, and institutional contexts. In these environments, we can find different cultural features that have an impact on students’ educational outcomes.
Logic Functions with Stimuli-Responsive Single Nanopores
2014
[EN] We present the concept of logic functions based on a single stimuli-responsive nanopore and analyze its potential for electrochemical transducers and actuators. The responsive molecules at the surface of the polymeric nanopore immersed in an electrolyte solution are sensitive to thermal, chemical, electrical, and optical stimuli, which are the input signals required to externally tune the conductance of the nanopore (the logical output). A single nanostructure can be operated as a resistor or as a diode with a broad range of rectifying properties, allowing for logical information-processing schemes that are useful pH and temperature sensors, electro-optical detectors, and electrochemic…
Multipore membranes with nanofluidic diodes allowing multifunctional rectification and logical responses
2016
[EN] We have arranged two multipore membranes with conical nanopores in a three-compartment electrochemical cell. The membranes act as tunable nanofluidic diodes whose functionality is entirely based on the pH-reversed ion current rectification and does not require specific surface functionalizations. This electrochemical arrangement can display different electrical behaviors (quasi-linear ohmic response and inward/outward rectifications) as a function of the electrolyte concentration in the external solutions and the applied voltage at the pore tips. The multifunctional response permits to implement different logical responses including NOR and INHIBIT functions.
Funcionamiento ejecutivo y rendimiento matemático: un estudio longitudinal
2016
El objetivo del presente estudio longitudinal consistió en examinar el poder predictivo de las funciones ejecutivas de inhibición y memoria de trabajo (MT) evaluadas en Educación Infantil (T1) sobre los aspectos formales e informales del rendimiento matemático en 2º de Educación Primaria (T2). La muestra inicial estuvo conformada por 209 preescolares de 5 a 6 años, de los que un 86.12 % de los sujetos volvieron a ser evaluados en el T2 (7-8 años). En el T1, se administraron seis tareas neuropsicológicas relacionadas con las funciones ejecutivas de inhibición y MT verbal y visoespacial. En el T2, se aplicó la batería TEMA-3 (Gingsburg y Baroody, 2003) para evaluar diferentes aspectos relacio…
A Multidimensional View of Children’s School Readiness
2016
The present longitudinal study explores, on the one hand, the nature and strengths of the relation between cognitive and behavioral self-regulation, and, on the other hand, the impact of early social, cognitive, and self-regulatory skills on later school achievement and social school adjustment. Findings indicate that working memory is the most important predictor of academic achievement in the longitudinal perspective; individual differences in social school adjustment, in contrast, were mainly explained by earlier behavioral self-regulatory skills. Executive functions, however, may additionally help us to understand the developmental mechanisms responsible for the successes and failures o…
Three-gluon Green functions: low-momentum instanton dominance and zero-crossing
2016
International audience; We will report on a some efforts recently made in order to gain a better understanding of some IR properties of the 3-point gluon Green function by following both lattice and continuum QCD approaches.