Search results for "G-DA"
showing 10 items of 11 documents
Lubricin is expressed in chondrocytes derived from osteoarthritic cartilage encapsulated in poly (ethylene glycol) diacrylate scaffold
2011
Osteoarthritis (OA) is characterized by degenerative changes within joints that involved quantitative and/or qualitative alterations of cartilage and synovial fluid lubricin, a mucinous glycoprotein secreted by synovial fibroblasts and chondrocytes. Modern therapeutic methods, including tissue-engineering techniques, have been used to treat mechanical damage of the articular cartilage but to date there is no specific and effective treatment. This study aimed at investigating lubricin immunohistochemical expression in cartilage explant from normal and OA patients and in cartilage constructions formed by Poly (ethylene glycol) (PEG) based hydrogels (PEG-DA) encapsulated OA chondrocytes. The e…
Aprendiendo Vibraciones Mec´anicas con Wolfram Mathematica
2015
[EN] Mechanical vibrations as subject can be found within many Engineering and Science Degrees. To achieve that the students understand the mathematics and its physical interpretation is the objective we should get as docents. In this paper we describe how to create a simple graphical model of a single degree of freedom vibrating system allowing us to visualize concepts like above concepts damping, resonance or forced vibrations. For that, we use the popular symbolic software Wolfram Mathematica with which, without an excessive programming complexity, we can obtain a very satisfactory visual model capable to move itself, controlled by parameters. In addition, the model incorporates the curv…
Varieties of agencies during working life changes
2020
The aim of this study is to shed light on the varieties of workers´ agencies in working life change situations, which is an under-researched topic in the literature of workplace learning and in working life studies. The research questions are what kinds of agencies there are to be found when workers encounter changes and how the different kinds of agencies are connected together. The understanding of agency is grounded on the subject-centered socio-cultural approach, whereas the methodological approach is based on applying life-course perspective on research material consisting of 48 working life narratives written by Finnish adults. The narratives are analyzed by abductive content analysis…
Semantic HMC for Big Data Analysis
2014
International audience; Analyzing Big Data can help corporations to im-prove their efficiency. In this work we present a new vision to derive Value from Big Data using a Semantic Hierarchical Multi-label Classification called Semantic HMC based in a non-supervised Ontology learning process. We also proposea Semantic HMC process, using scalable Machine-Learning techniques and Rule-based reasoning.
The affect of contact force sensations on user performance in virtual assembly tasks
2007
International audience; Abstract The development of a realistic virtual assemblyenvironment is challenging because of the complexity of the physical processes and the limitation of available VRtechnology. Many research activities in this domain pri-marily focused on particular aspects of the assembly task such as the feasibility of assembly operations in terms of interference between the manipulated parts. The virtualassembly environment reported in this research is focusedon mechanical part assembly. The approach presented ad-dresses the problem of part-to-part contacts during themating phase of assembly tasks. The system describedcalculates contact force sensations by making their inten-s…
Metabolic flux understanding of Pichia pastoris grown on heterogenous culture media
2014
[EN] Within the emergent field of Systems Biology, mathematical models obtained from physical chemical laws (the so-called first principles-based models) of microbial systems are employed to discern the principles that govern cellular behaviour and achieve a predictive understanding of cellular functions. The reliance on this biochemical knowledge has the drawback that some of the assumptions (specific kinetics of the reaction system, unknown dynamics and values of the model parameters) may not be valid for all the metabolic possible states of the network. In this uncertainty context, the combined use of fundamental knowledge and data measured in the fermentation that describe the behaviour…
Does the brain know who is at the origin of what in an imitative interaction?
2012
International audience; Brain correlates of the sense of agency have recently received increased attention. However, the explorations remain largely restricted to the study of brains in isolation. The prototypical paradigm used so far consists of manipulating visual perception of own action while asking the subject to draw a distinction between self- versus externally caused action. However, the recent definition of agency as a multifactorial phenomenon combining bottom-up and top-down processes suggests the exploration of more complex situations. Notably there is a need of accounting for the dynamics of agency in a two-body context where we often experience the double faceted question of w…
MediaDASH Tool: Plataforma Web para la Codificación, Difusión y Recepción de Videos DASH
2017
[ES] Hoy en día el tráfico de video de internetsignifica alrededor del 65-70% del tráfico total. Se prevéque en 2019 aumente hasta el 80%. Debido a esto se hacenecesario optimizar y mejorar las tecnologías relacionadascon la transmisión de video para garantizar una calidad deexperiencia adecuada. Es por ello que se están desarrollando nuevos protocolos de transmisión de videoadaptativos basados en DASH. Debido a que su uso estáaumentando en los últimos años para realizar streamingsobre HTTP. En este artículo presentamos la herramientaMediaDASH Tool, la cual es una aplicación web quepermite de manera muy intuitiva poder comprimir ypreparar videos para su difusión con DASH. Así como suposteri…
A Reconsideration of the Role of Forward-Market Arbitrage in Keynes’s and Hicks’s Theories of the Term Structure of Interest Rates
2014
International audience; This paper develops the relationship between Hicks’s and Keynes’s writings on the theory of the term structure of interest rates, and shows in detail how Hicks built on and extended Keynes’s account. According to this theory, the level of the long-term interest rate is determined by expectations of future short-term rates. Keynes’s thinking contained several notions – such as the preferred habitat of lenders, the theory of forward markets, and risk-premiums – which Hicks used to give a more complete theory of the term structure of interest rates. Besides implementing these notions in his own theory, Hicks introduced the concepts of the preferred habitat of borrowers,…
Limits to Arbitrage and Interest Rates: a Debate Between Keynes, Hawtrey and Hicks
2018
International audience; This paper deals with a debate between Hawtrey, Hicks and Keynes concerning the capacity of the central bank to influence the short-term and the long-term rates of interest. Both Hawtrey and Keynes considered the central bank’s ability to influence short-term rates of interest. However, they do not put the same emphasis on the study of the long-term rates of interest. According to Keynes, long-term rates are influenced by future expected short-term rates (1930, 1936), whereas for Hawtrey (1932, 1937, 1938), long-term rates are more dependent on the business cycle. Short-term rates do not have much effect on long-term rates according to Hawtrey. In 1939, Hicks enters …