Search results for "GARP"

showing 5 items of 5 documents

Large-scale distribution analysis of Antarctic echinoids using ecological niche modelling.

2012

Understanding the factors that determine the distribution of taxa at various spatial scales is a crucial challenge in the context of global climate change. This holds particularly true for polar marine biota that are composed of both highly adapted and vulnerable faunas. We analysed the distribution of 2 Antarctic echinoid species, Sterechinus antarcticus and S. neumayeri, at the scale of the entire Southern Ocean using 2 niche modelling procedures. The performance of distribution models was tested with regard to the known ecology of the species. The respective contributions of environmental parameters are discussed along with the putative roles played by biotic interactions and biogeograph…

0106 biological sciencesContext (language use)Aquatic ScienceHabitat suitability map010603 evolutionary biology01 natural sciences[SDV.EE.ECO]Life Sciences [q-bio]/Ecology environment/EcosystemsGARPSea ice14. Life underwaterSouthern OceanEcology Evolution Behavior and SystematicsPolar frontEcological nichegeography[ SDE.BE ] Environmental Sciences/Biodiversity and Ecologygeography.geographical_feature_categoryBiotic componentEcologybiologyEcology010604 marine biology & hydrobiologyEchinoidea15. Life on landbiology.organism_classificationSterechinus[ SDV.EE.ECO ] Life Sciences [q-bio]/Ecology environment/EcosystemsSterechinusOceanographyArctic13. Climate actionEchinoidea [Sea urchins]Biological dispersal[SDE.BE]Environmental Sciences/Biodiversity and EcologyMaxent
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Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

2020

Platelets have been recently described as an important component of the innate and adaptive immunity through their interaction with immune cells. However, information on the platelet&ndash

0301 basic medicineCancer Researchmedicine.medical_treatmentT cellanimal diseaseschemical and pharmacologic phenomenathrombocytosisBiologylcsh:RC254-282Article03 medical and health sciences0302 clinical medicineImmune systemGARPDownregulation and upregulationmedicinemelanomaPlateletIL-2 receptorFOXP3Immunotherapybiochemical phenomena metabolism and nutritionAcquired immune systemlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensTreg030104 developmental biologymedicine.anatomical_structureOncology030220 oncology & carcinogenesisplateletsCancer researchbacteriaCancers
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Noninvasive ventilation for acute hypoxemic respiratory failure/ARDS: The show must go on

2018

0301 basic medicinemedicine.medical_specialtyARDSAcute hypoxemic respiratory failureEmergency Medicine; Anesthesiology and Pain Medicinebusiness.industryNon-invasive ventilation in hypoxemic respiratory failure/ards | GREGORETTI CORTEGIANI RAINERI GIARRATANO VS. HILL GARPESTAD SCHUMAKER SPOLETINImedicine.disease03 medical and health sciences030104 developmental biologyAnesthesiology and Pain MedicineEmergency MedicineMedicineNoninvasive ventilationbusinessIntensive care medicine
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GARP: A Key Target to Evaluate Tumor Immunosuppressive Microenvironment

2021

Simple Summary Tumors are not only composed of cancer cells but also of various infiltrating cells constituting the tumor microenvironment (TME); all these cells produce growth factors which contribute to tumor progression and invasiveness. Among them, transforming growth factor-β1 (TGF-β1) has been shown to be a potent immunosuppressive cytokine favoring cell proliferation and invasion and to be associated with resistance to anticancer treatments. Glycoprotein-A repetition predominant (GARP) plays a critical role in the activation of TGF-β1 and has been shown to be expressed at the membrane of cancer cells and also of regulatory T cells and platelets in the TME. An increased GARP expressio…

TGF-βTumor microenvironmentimmunosuppressionGeneral Immunology and MicrobiologyQH301-705.5CancerReviewBiologymedicine.diseaseGeneral Biochemistry Genetics and Molecular BiologyBiomarker (cell)Docking (dog)Immune systemGARPCancer researchmedicinecancerbiomarkerBiology (General)General Agricultural and Biological SciencesReceptorFunction (biology)Transforming growth factorBiology
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Noninvasive Ventilation in Hypoxemic Patients: an Ongoing Soccer Game or a Lost One?

2017

[This corrects the article on p. 329 in vol. 45, PMID: 29359070.].

medicine.medical_specialtyEmergency Medicine; Anesthesiology and Pain Medicinebusiness.industryNon-Invasive Ventilation in Hypoxemic Respiratory Failure/ARDS GREGORETTI CORTEGIANI RAINERIGIARRJATANO VS. HILL GARPESTAD SCHUMAKER SPOLETINI03 medical and health sciences0302 clinical medicineAnesthesiology and Pain Medicine030228 respiratory systemEmergency medicinemedicineEmergency MedicineNoninvasive ventilation030212 general & internal medicineErratumbusiness
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