Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

6533b82ffe1ef96bd12951ad

RESEARCH PRODUCT

Platelet-Derived GARP Induces Peripheral Regulatory T Cells—Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis

Niklas Zimmer Sophia Zimmer Stephan Grabbe Franziska K. Krebs Carmen Loquai Kerstin Jurk Elena J. Kumm Heidrun Mitzel-rink Andrea Tuettenberg

subject

0301 basic medicine Cancer Research medicine.medical_treatment T cell animal diseases chemical and pharmacologic phenomena thrombocytosis Biology lcsh:RC254-282 Article 03 medical and health sciences 0302 clinical medicine Immune system GARP Downregulation and upregulation medicine melanoma Platelet IL-2 receptor FOXP3 Immunotherapy biochemical phenomena metabolism and nutrition Acquired immune system lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Treg 030104 developmental biology medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis platelets Cancer research bacteria

description

Platelets have been recently described as an important component of the innate and adaptive immunity through their interaction with immune cells. However, information on the platelet&ndash

year	journal	country	edition	language
2020-12-05	Cancers

10.3390/cancers12123653 https://www.mdpi.com/2072-6694/12/12/3653

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