Search results for "GDO"
showing 10 items of 382 documents
Miljøterapeutteam i barneverntjenesten : Evaluering av miljøterapeutteam i barnevernstjenesten i Kristiansand kommune
2013
Systematisk bruk av miljøterapeutiske tilnærminger til barn og familier i barnevernet anvendes i varierende grad. Miljøterapeutteamet er et hjemmebasert tiltak for familier som er i behov at hjelpetiltak etter lov om barneverntjenester § 4-4. Tiltaket er et førstelinjetilbud i Kristiansand barneverntjeneste. Familiene som teamet arbeider med blir henvist fra barneverntjenestens saksbehandlere. Etter ønske fra ledelsen i barneverntjenesten ble teamet opprettet for å arbeide målrettet inn i familier i en avgrenset periode. Hensikten var å gi målrettede og virkningsfulle hjelpetiltak i en presset situasjon hvor mye tid og ressurser gikk til meldingsgjennomganger, undersøkelser, tiltakssaker og…
Næromsorgsør : En evaluering av et hjemmebasert tiltak for jenter i alderen 14-18 år
2007
Denne rapporten er en beskrivende evaluering av Næromsorg Sør`s arbeid med jenter i alderen 14-18 år. Næromsorg Sør er en privat stiftelse som presenterer seg blant annet som et tiltak som retter fokus på jenter og gutter i alderen 13-18 år, der rus-, psykiatri- eller atferdsproblematikk er utprega, og deres familier. Det er et nærmiljø- /næromsorgstiltak, som også kan være et alternativ til institusjonsplassering. Det jobbes med relasjoner og målet er å skape ny mestringstillit både hos jenta/gutten og familien. Tiltaket benyttes av barneverntjenesten som et hjelpetiltak med hjemmel i Lov om barneverntjenester § 4-4, første ledd. Problemene til jentene som utgjør utvalget i denne undersøke…
United in the Commonwealth. The participation of Lithuanian troops in the Zborów battle in 1649
2018
Abstract In 1648, an uprising broke out in Ukraine that belonged to Poland at the time. The war was not successful for the Polish-Lithuanian Commonwealth. The Cossacks and Tartars, who were helping them during the war, surrounded Zbaraż, about whose defense everyone knew in the country. King Jan Kazimierz decided to set out to rescue the besieged fortress. It was decided that not only Polish troops, but also soldiers of Lithuania would set out for Ukraine. Not only state armies, but also private regiments set out to fight. The article discusses the problem of the reasons for the participation of Lithuanians in the war, which was not only due to the provisions of the union, but also to be in…
BBE31 from the Lyme disease agent Borrelia burgdorferi, known to play an important role in successful colonization of the mammalian host, shows the a…
2019
Abstract Lyme disease is a tick-borne infection caused by Borrelia burgdorferi sensu lato complex spirochetes. The spirochete is located in the gut of the tick; as the infected tick starts the blood meal, the spirochete must travel through the hemolymph to the salivary glands, where it can spread to and infect the new host organism. In this study, we determined the crystal structures of the key outer surface protein BBE31 from B. burgdorferi and its orthologous protein BSE31 (BSPA14S_RS05060 gene product) from B. spielmanii. BBE31 is known to be important for the transfer of B. burgdorferi from the gut to the hemolymph in the tick after a tick bite. While BBE31 exerts its function by intera…
How school nurses experience and understand everyday pain among adolescents
2017
Abstract Background Pain problems are a rapidly growing health problem found among both children and adolescent, and about 15–30% have reported chronic pain problems. School nurses in Norway meet adolescents with various ailments, including pain. Yet research on how school nurses perceive the pain experienced by adolescents is limited. The aim of the present study was to explore how school nurses explain and experience the everyday pain of adolescents. Method A qualitative study with an explorative design comprising five focus group interviews. Each group consisted of three to five school nurses. Seventeen female school nurses in five junior high schools in Norway, age range 29–65 years par…
Borrelia burgdorferi ārējās virsmas proteīnu BB0689 un BBA73 funkcionālie pētījumi
2015
Maģistra darbs veidots ar mērķi noskaidrot B. burgdorferi ārējās virsmas proteīnu BB0689 un BBA73 potenciālo lomu patogēna un saimniekorganisma mijiedarbībā, kas varētu paplašināt mūsu zināšanas par Laimboreliozes patoģenēzi. Borēlijas proteīnu un zīdītāju vai artropodu proteīnu iespējamā mijiedarbība ir noteikta, izmantojot Ni-NTA afinitātes hromatogrāfiju, proteīnu kompleksu imūnprecipitāciju (Co-Ip) un attālināto Western blotu. Konstatēto mijiedarbības partneru identifikācijai ir izmantota MALDI-TOF masas spektrometrija. Pētījuma rezultātā ir konstatēta BB0689 iespējamā saistība ar vairākiem zīdītāju proteīniem, savukārt BBA73 gadījumā ir novērota tā mijiedarbība ar Ixodes ērču proteīnie…
Laimas slimības ierosinātāja Borrelia burgdorferi ārējās virsmas proteīna BB0663 iegūšana un struktūras analīze
2019
Darba mērķis bija iegūt Laimas slimības izraisītāja Borrelia burgdorferi (B. burgdorgeri) celma B31 ārējās virsmas proteīna BB0663 struktūru un veikt šīs struktūras analīzi, lai iegūtu plašākas zināšanas par baktērijas patoģenēzes mehānismiem. Darba rezultātā BB0663 proteīns tika uzproducēts Escherichia coli šūnās, attīrīts un kristalizēts. Ar rengenstruktūranalīzes palīdzību tika iegūti šī kristāla difrakcijas dati. Izmantojot iegūtos datus, tika noteikta BB0663 proteīna 3D struktūra. Struktūras analīze parādīja, ka B. burgdorferi BB0663 proteīns ir līdzīgs baktērijas Novosphingobium aromaticivorans (N. aromaticivorans) proteīnam, kuram ir noteikta struktūra, bet nav zināma funkcija. Pētīj…
Unraveling the pleomorphic forms of Borrelia burgdorferi
2014
Borrelia burgdorferi bakteeri on puutiaisten välittämän borrelioosin taudinaiheuttaja. Tämä tavanomaisesti spirokeettana esiintyvä bakteeri kykenee vaihtamaan muotoaan ympäristöolosuhteiden muuttuessa epäsuotuisiksi. Borrelia-bakteerin eri esiintymismuotojen uskotaan olevan borrelioosin pitkittyneen taudinkuvan takana, minkä vuoksi näiden muotojen tutkiminen on tärkeää. Tämän pro gradu –työn tavoitteena oli tutkia B. burgdorferin pleomorfisia muotoja ja löytää muotoja erottavia morfologisia tekijöitä sekä eroja proteiiniekspressiossa ja borrelioosipotilasseerumivasteessa spirokeettojen ja pyöreän esiintymismuodon välillä. Olettamuksena oli, että konfokaalimikroskopialla muotojen väliltä löy…
The association between extremely low-frequency electromagnetic fields and childhood leukaemia in epidemiology: enough is enough?
2010
Background: Previous pooled analyses have reported an association between magnetic fields and childhood leukaemia. We present a pooled analysis based on primary data from studies on residential magnetic fields and childhood leukaemia published after 2000. Methods: Seven studies with a total of 10 865 cases and 12 853 controls were included. The main analysis focused on 24-h magnetic field measurements or calculated fields in residences. Results: In the combined results, risk increased with increase in exposure, but the estimates were imprecise. The odds ratios for exposure categories of 0.1–0.2 μT, 0.2–0.3 μT and ⩾0.3 μT, compared with <0.1 μT, were 1.07 (95% CI 0.81–1.41), 1.16 (0.69–1.93)…
Incidence, Medical Resource Utilisation and Costs of Hyperuricemia and Tumour Lysis Syndrome in Patients with Acute Leukaemia and Non-Hodgkin's Lymph…
2003
Hyperuricemia (HU) and tumour lysis syndrome (TLS) are complications of acute leukaemia and non-Hodgkin lymphoma (NHL) leading to increased morbidity and mortality. The objective of this study was to define incidence and calculate health care cost associated with HU and TLS. 788 acute leukaemia and NHL patients from Belgium, The Netherlands, Spain and UK were screened retrospectively for HU and TLS. Resource use related to HU and TLS was recorded and costs were calculated applying local unit costs. Results showed that HU occurred in 18.9% of patients, and 27.8% of them fulfilled TLS criteria. The cost of HU without TLS was 672 euros (SE 181), the cost of TLS 7,342 euros (SE 1,412). TLS requ…