Search results for "GENI"
showing 10 items of 6843 documents
Neuroendocrine Tumors: A Comprehensive Review on Nutritional Approaches.
2022
Simple Summary Neuroendocrine neoplasms and their main subtype neuroendocrine tumors have an increasing incidence worldwide, associated with a high survival and prevalence rate. Both the tumor itself and systemic therapy can have an impact on patients' nutrition. Conversely, preliminary data suggest that malnutrition has a negative impact on the development and prognosis of neuroendocrine tumors, as does obesity. The aim of this review is to condense the latest evidence on the role of the most widely used dietary patterns, the Mediterranean diet, the ketogenic diet and intermittent fasting, in the context of neuroendocrine tumors. Nutritional plans are an integral part of the multidisciplin…
THE ROLE OF NEUROMODULATORS (SUBSTANCE P AND CALCITONINE GENE-RELATED PEPTIDE) IN THE DEVELOPMENT OF NEUROGENIC INFLAMMATION IN THE ORAL MUCOSA
2004
Vatous observations carried out in the course of the years have shown that certain neuropeptides have a possible role to play as inflammation mediators. The substances on which attention has been principally focused are: substance P, calcitonin gene-related peptide, capsaicin an histamine. Knowledge acquired in this field, however, does not yet permit us to sufficiently clarify the role, not to speak of the possible action mechanism, on the basis of which these neuropeptides act, although it is confirmed that these substances have been found first in laboratory animals and later also in human tissues in the course of experimentally induced neurogenic inflammation. The need to know more and …
NEURONS AND ASTROCYTES SHED EXTRACELLULAR VESICLES THAT SEEM TO VEHICLE ANGIOGENIC FACTORS
2007
Macroscytus raunoi, a new burrower bug species from Papua New Guinea (Hemiptera: Heteroptera: Cydnidae: Cydninae)
2016
Abstract Macroscytus raunoi, a new species of the genus Macroscytus Fieber, 1860, is described from the Morobe Province on the northern coast of Papua New Guinea. The new species is similar in its morphological characters to Australian M. arnhemicus J. A. Lis, 1999. Differences in morphology and male genitalia which enable separation of both species are provided.
Targeting the tumor mutanome for personalized vaccination therapy
2012
Next generation sequencing enables identification of immunogenic tumor mutations targetable by individualized vaccines. In the B16F10 melanoma system as pre-clinical proof-of-concept model, we found a total of 563 non-synonymous expressed somatic mutations. Of the mutations we tested, one third were immunogenic. Immunization conferred in vivo tumor control, qualifying mutated epitopes as source for effective vaccines.
Estrés agudo en niños intervenidos quirúrgcamente y sintomatología en sus progenitores
2013
La intervención quirúrgica (IQ) en la infancia representa un estrés potencial para el niño y sus familiares. La ansiedad es una de las reacciones más frecuentes. Respecto al estrés, existe una transmisión de emociones entre los progenitores y el niño IQ (intervenido quirúrgicamente). Es difícil separar los efectos de la hospitalización y sus consecuencias de las experiencias traumáticas de los niños IQ y su familia por lo que el estrés se ha investigado en relación al desarrollo psicosocial del niño, las reacciones psicológicas y físicas, la enfermedad y la hospitalización. Durante la enfermedad, diversos estudios muestran la correlación entre la ansiedad del niño y la de sus padres (Kain, …
Noiseless Quantum Measurement and Squeezing of Microwave Fields Utilizing Mechanical Vibrations
2017
A process which strongly amplifies both quadrature amplitudes of an oscillatory signal necessarily adds noise. Alternatively, if the information in one quadrature is lost in phase-sensitive amplification, it is possible to completely reconstruct the other quadrature. Here we demonstrate such a nearly perfect phase-sensitive measurement using a cavity optomechanical scheme, characterized by an extremely small noise less than 0.2 quanta. We also observe microwave radiation strongly squeezed by 8 dB below vacuum. A source of bright squeezed microwaves opens up applications in manipulations of quantum systems, and noiseless amplification can be used even at modest cryogenic temperatures.
Framework for ubiquitous and voice enabled web applicattions development.
2004
La cantidad de dispositivos con capacidad de conexión a Internet crece rápidamente. En la actualidad se dispone de teléfonos móviles basados en tecnología WAP (Wireless Application Protocol) o I-Mode, Agendas Digitales Personales, Kioskos Internet, teléfonos convencionales basados en acceso a la Web por medio de la voz, dispositivos basados en televisión interactiva, electrodomésticos, entre otros. Desarrollar una versión de una aplicación web para cada uno de los dispositivos con conectividad a la Web resulta inviable. Por otra parte, desarrollar aplicaciones web que puedan ser visualizados en forma apropiada y aprovechando al máximo las capacidades del dispositivo se constituye en una tar…
Non-target and biological diversity risk assessment
2008
This chapter discusses the following procedures for risk assessment in Bt cotton using the non-target risk assessment model developed by scientists of the GMO ERA Project ("International Project on GMO Environmental Risk Assessment Methodologies", which is a continuation of the GMO Guidelines Project, which was launched by scientists of the International Organization for Biological Control Global Working Group on "Transgenic Organisms in Integrated Pest Management and Biological Control"): (1) identify relevant functional groups of biological diversity associated with adverse effects, (2) list and prioritize species or ecological processes, (3) identify potential exposure pathways and adver…
Substrate specificity screening of oat (Avena sativa) seeds aminopeptidase demonstrate unusually broad tolerance in S1 pocket.
2012
Aminopeptidases are proteolytic enzymes that remove one amino acid at a time from N-terminus of peptidic substrates. In plants, inhibitors of aminopeptidases can find potential applications in agriculture as herbicides. In this report we have used a library of fluorogenic derivatives of natural and unnatural amino acids for substrate specificity profiling of oat (Avena sativa) aminopeptidase. Interestingly, we have found that this enzyme recognizes effectively among the natural amino acids basic residues like Arg and Lys, hydrophobic Phe, Leu and Met, but also to some extent acidic residues Asp and Glu. In the case of unnatural amino acids hydrophobic residues (hPhe and hCha) and basic hArg…