Search results for "GOALS"

showing 10 items of 643 documents

Towards nonlocal density functionals by explicit modelling of the exchange-correlation hole in inhomogeneous systems

2013

We put forward new approach for the development of a non-local density functional by a direct modeling of the shape of exchange-correlation (xc) hole in inhomogeneous systems. The functional is aimed at giving an accurate xc-energy and an accurate corresponding xc-potential even in difficult near-degeneracy situations such as molecular bond breaking. In particular we demand that: (1) the xc hole properly contains -1 electron, (2) the xc-potential has the asymptotic -1/r behavior outside finite systems and (3) the xc-potential has the correct step structure related to the derivative discontinuities of the xc-energy functional. None of the currently existing functionals satisfies all these re…

FOS: Physical sciences02 engineering and technologyElectronClassification of discontinuities01 natural sciencesDFTCondensed Matter - Strongly Correlated ElectronsAtomic orbitalQuantum mechanicsPhysics - Chemical Physics0103 physical sciencesPhysics - Atomic and Molecular ClustersSDG 7 - Affordable and Clean Energy010306 general physicsEnergy functionalChemical Physics (physics.chem-ph)PhysicsQuantum Physics/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyStrongly Correlated Electrons (cond-mat.str-el)ta114theoretical nanoscienceFunction (mathematics)021001 nanoscience & nanotechnologyAtomic and Molecular Physics and OpticsCondensed Matter - Other Condensed MatterDensity functional theorySum rule in quantum mechanicsLocal-density approximationAtomic and Molecular Clusters (physics.atm-clus)Quantum Physics (quant-ph)0210 nano-technologyOther Condensed Matter (cond-mat.other)Physical Review A
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Observation of Photon Polarization in theb→sγTransition

2014

This Letter presents a study of the flavor-changing neutral current radiative $B^{\pm} \to K^{\pm}\pi^{\mp}\pi^{\pm}\gamma$ decays performed using data collected in proton-proton collisions with the LHCb detector at $7$ and $8\,$TeV center-of-mass energies. In this sample, corresponding to an integrated luminosity of $3\,\text{fb}^{-1}$, nearly $14\,000$ signal events are reconstructed and selected, containing all possible intermediate resonances with a $K^{\pm}\pi^{\mp}\pi^{\pm}$ final state in the $[1.1, 1.9]\,$GeV/$c^{2}$ mass range. The distribution of the angle of the photon direction with respect to the plane defined by the final-state hadrons in their rest frame is studied in interva…

Final statePhotonmedia_common.quotation_subject14.40.NdHadronGeneral Physics and AstronomyLHCb - Abteilung Hofmann12.15.MmAsymmetryHigh energy physics Polarization Tellurium compounds; Center-of-mass energies Direct observations Final state Flavor-changing neutral current Integrated luminosity Photon polarization Proton proton collisions; PhotonsNeutral currentNuclear physicsTellurium compoundsCenter-of-mass energiesPhysics and Astronomy (all)Flavor-changing neutral currentPolarizationPhoton polarizationLeptonic semileptonic and radiative decays of bottom mesonRadiative transferIntermediate stateSDG 7 - Affordable and Clean EnergyHigh energy physicsQCmedia_commonPhysicsIntegrated luminosityPhotons/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyProton proton collisionsNeutral currentDirect observationsParticle physicsRest framePhoton polarizationLHCb13.20.HeBottom mesons (|B|>0)High Energy Physics::ExperimentLHCFísica de partículesExperimentsPhysical Review Letters
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Continuous experimentation on artificial intelligence software : a research agenda

2020

Moving from experiments to industrial level AI software development requires a shift from understanding AI/ ML model attributes as a standalone experiment to know-how integrating and operating AI models in a large-scale software system. It is a growing demand for adopting state-of-the-art software engineering paradigms into AI development, so that the development efforts can be aligned with business strategies in a lean and fast-paced manner. We describe AI development as an “unknown unknown” problem where both business needs and AI models evolve over time. We describe a holistic view of an iterative, continuous approach to develop industrial AI software basing on business goals, requiremen…

Focus (computing)Future studiesComputer sciencebusiness.industrysoftwareContinuous experimentationohjelmistotuotantoSoftware development020207 software engineeringArtificial intelligence software02 engineering and technologytekoälytutkimustoimintaartificial intelligenceGeneralLiterature_MISCELLANEOUSEngineering managementBusiness goalsSoftwareComputingMethodologies_PATTERNRECOGNITION020204 information systems0202 electrical engineering electronic engineering information engineeringSoftware systembusinessohjelmistokehitys
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Mind the gap—deficits in our knowledge of aspects impacting the bioavailability of phytochemicals and their metabolites—a position paper focusing on …

2015

This is an open access article under the terms of the Creative Commons Attribution-Non-Commercial-NoDerivs Licence.-- et al.

Food processingColonFood HandlingMetabolitePhytochemicalsBiological AvailabilityReviewsReviewPharmacologyBiologymedicine.disease_causeGastrointestinal epitheliumchemistry.chemical_compoundSDG 3 - Good Health and Well-beingBiotransformationsIntestine SmallmedicineHumansTissue DistributionCarotenoidBiotransformationchemistry.chemical_classificationMicrobiotaPolyphenolsCarotenoidsGastrointestinal MicrobiomeBioavailabilityTransportersIntestinal AbsorptionSolubilityPhytochemicalBiochemistrychemistryPolyphenol/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingEffluxOxidative stressMixed dietFood ScienceBiotechnologyMolecular Nutrition & Food Research
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Prediction of Distant Educational Goals by Goals in Other Domains and Perceived Contextual Opportunities

2015

<p class="western" style="margin-bottom: 0cm; line-height: 150%;" lang="en-US"><span style="color: #000000;"><span style="font-family: Times New Roman,serif;">Lifelong learning is linked to successful economic participation</span></span><span style="color: #0000ff;"><span style="font-family: Times New Roman,serif;">. </span></span><em><span style="font-family: Times New Roman,serif;"><span style="font-style: normal;">At the same time, individual activities are framed by contextual opportunities for education and occupation.</span></span></em><span style="color: #000000;"><span style="font-fami…

Further educationLiving placeLifelong learningcontextual opportunities; education; emerging adults; personal goalsContext (language use)PsychologyLife domainAssociation (psychology)Social psychologySOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference
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Effect of sodium borohydride and hydrogen peroxide pretreatments on soda pulping of sugar maple (Acer saccharum)

2021

For recovering value-added wood-based organic material prior to delignification, sodium borohydride (NaBH4) and hydrogen peroxide (H2O2) pretreatments under alkaline conditions were performed before soda pulping of sugar maple (Acer saccharum) chips with sodium hydroxide (NaOH). In this investigation, it was determined whether the pulp yield could be increased by partly stabilizing the hemicelluloses by these pretreatments, and simultaneously obtains lower pulp kappa numbers. The results indicated that when aiming to the same kappa numbers (i.e., kappa numbers 14.3-20.5), roughly 3% higher pulp yield could be achieved if the chips were pretreated with alkaline 0.5% NaBH4 solutions, compared…

General Chemical EngineeringAcer saccharumengineering.material/dk/atira/pure/sustainabledevelopmentgoals/responsible_consumption_and_productionchemistry.chemical_compoundSodium borohydridestomatognathic systemGeneral Materials ScienceSugarHydrogen peroxide/dk/atira/pure/sustainabledevelopmentgoals/industry_innovation_and_infrastructureInnovationSodium borohydrideMapleChemistrySoda cookingGeneral ChemistryPulp and paper industryHydrogen peroxidestomatognathic diseasesSugar mapleSoda pulpingengineeringand InfrastructureSDG 9 - Industry Innovation and InfrastructureSDG 12 - Responsible Consumption and ProductionSDG 9 - IndustryPretreatmentJournal of Wood Chemistry and Technology
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GUI Implementation of VCDtools, A Program to Analyze Computed Vibrational Circular Dichroism Spectra

2020

As computing power increases, vibrational circular dichroism (VCD) calculations on molecules of larger sizes and complexities become possible. At the same time, the spectra resulting from these computations become increasingly more cumbersome to analyze. Here, we describe the GUI implementation into the Amsterdam Density Functional (ADF) software package of VCDtools, a toolbox that provides a user-friendly means to analyze VCD spectra. Key features are the use of the generalized coupled oscillator analysis methods, as well as an easy visualization of the atomic electric and magnetic transition dipole moments which together provide detailed insight in the origin of the VCD intensity. Using s…

General Chemical EngineeringComputationLibrary and Information Sciences01 natural sciencesSpectral lineArticle0103 physical sciencesSDG 7 - Affordable and Clean EnergyAnalysis methodFELIX Condensed Matter PhysicsPhysics/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy010304 chemical physicsCircular DichroismStereoisomerismGeneral ChemistryKey featuresSoftware package0104 chemical sciencesComputer Science ApplicationsVisualizationComputational physics010404 medicinal & biomolecular chemistryDipoleVibrational circular dichroismSoftwareJournal of Chemical Information and Modeling
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First experimental study of photon polarization in radiative B0s decays.

2017

The polarization of photons produced in radiative $B^{0}_{s}$ decays is studied for the first time. The data are recorded by the LHCb experiment in $pp$ collisions corresponding to an integrated luminosity of 3fb$^{-1}$ at center-of-mass energies of $7$ and $8$TeV. A time-dependent analysis of the $B^{0}_{s} \to \phi \gamma$ decay rate is conducted to determine the parameter ${\mathcal{A}}^\Delta$, which is related to the ratio of right- over left-handed photon polarization amplitudes in $b \to s \gamma$ transitions. A value of ${\mathcal{A}}^\Delta=-0.98^{\,+0.46\,+0.23}_{\,-0.52\,-0.20}$ is measured. This result is consistent with the Standard Model prediction within two standard deviatio…

General PhysicsPhotonModels beyond the standard modeldistributions asymmetries toolPhysics MultidisciplinaryGeneral Physics and AstronomyFOS: Physical sciences01 natural sciencesHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareNONuclear physicsPhysics and Astronomy (all)High Energy Physics - Experiment (hep-ex)ASYMMETRIES0103 physical sciencesPhoton polarizationLeptonic semileptonic and radiative decays of bottom mesonDISTRIBUTIONS; ASYMMETRIES; TOOLRadiative transfer[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]DISTRIBUTIONSTOOLSDG 7 - Affordable and Clean Energy010306 general physicsPhysicsScience & Technology02 Physical Sciences/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energyhep-ex010308 nuclear & particles physicsPhysicsParticle physicsPolarization (waves)HEPB physics photon polarization.3. Good healthLHCbAmplitudePhysical SciencesBottom mesons (|B|>0)High Energy Physics::ExperimentLHCFísica de partículesExperimentsPolarization in interactions and scatteringParticle Physics - Experiment
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Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

2018

Background: DNA methylation at the GFI1-locus has been repeatedly associated with exposure to smoking from the foetal period onwards. We explored whether DNA methylation may be a mechanism that links exposure to maternal prenatal smoking with offspring's adult cardio-metabolic health.Methods: We meta-analysed the association between DNA methylation at GFI1-locus with maternal prenatal smoking, adult own smoking, and cardio-metabolic phenotypes in 22 population-based studies from Europe, Australia, and USA (n= 18,212). DNA methylation at the GFI1-locus was measured in whole-blood. Multivariable regression models were fitted to examine its association with exposure to prenatal and own adult s…

Genetics and Molecular Biology (all)MaleNetherlands Twin Register (NTR)0301 basic medicineResearch paperGFI1 protein humanGFI1-locusraskausResearch & Experimental Medicinecardio-metabolic phenotypesBiochemistryEpigenesis GeneticGLOBAL Meth QTL Consortium0302 clinical medicinePregnancySmoke030212 general & internal medicinematernal prenatal smokingDNA METHYLATIONmedia_commonRISK2. Zero hungereducation.field_of_studySmokingta3142General MedicineMiddle Agedgenetics [Transcription Factors]3. Good healthDNA-Binding ProteinsPhenotypeMedicine Research & ExperimentalCARDIOVASCULAR-DISEASEepigenetiikkaPopulation SurveillancePrenatal Exposure Delayed EffectsDNA methylation/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleDisease SusceptibilityBIOS ConsortiumMedical GeneticsLife Sciences & BiomedicineAdultmedicine.medical_specialtyOffspringBirth weightPopulationMothersgenetics [DNA-Binding Proteins]ta3111MethylationGeneral Biochemistry Genetics and Molecular BiologyDIET03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingtupakointiGeneral & Internal MedicineInternal medicine/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_medicinemedia_common.cataloged_instanceHumansddc:610adverse effects [Maternal Exposure]EXPOSUREEpigeneticsEuropean unioneducationMedicinsk genetikEPIGENOME-WIDE ASSOCIATIONPregnancyBiochemistry Genetics and Molecular Biology (all)Science & Technologybusiness.industryadverse effects [Smoking]DNA Methylationta3121medicine.diseaseBIRTH-WEIGHT030104 developmental biologyEndocrinologyGenetic Locisydän- ja verisuonitauditCpG IslandsCIGARETTE-SMOKINGCESSATIONEnergy Metabolismmetabolism [Myocardium]businessBody mass indexBiomarkersTranscription FactorsEBioMedicine
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No association between two polymorphisms of the serotonin transporter gene and combined type attention deficit hyperactivity disorder.

2008

Contains fulltext : 71091.pdf (Publisher’s version ) (Closed access) Several independent studies have reported association between serotonin transporter gene (SLC6A4) polymorphisms and attention deficit hyperactivity disorder (ADHD). Five studies found evidence for association between the long-allele of a 44-bp insertion/deletion polymorphism (5-HTTLPR) and ADHD. Another two studies corroborated this finding while a further six studies did not find such an association. For a second polymorphism within the gene, a variable number tandem repeat (VNTR) within intron 2, one study demonstrated that the 12/12 genotype was significantly less frequent in ADHD cases compared to controls, while a sec…

Genetics and epigenetic pathways of disease [NCMLS 6]MedizinNeuroinformatics [DCN 3]0302 clinical medicinePolymorphism (computer science)GenotypePerception and Action [DCN 1]Childhealth care economics and organizationsSerotonin transporterGenetics (clinical)GeneticsSerotonin Plasma Membrane Transport Proteins0303 health sciencesDepression030305 genetics & heredityTransmission disequilibrium testhumanitiesVariable number tandem repeatPsychiatry and Mental healthChild Preschool/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFunctional Neurogenomics [DCN 2]medicine.medical_specialtyAdolescenteducationBiologybehavioral disciplines and activitiesMental health [NCEBP 9]Genomic disorders and inherited multi-system disorders [IGMD 3]03 medical and health sciencesCellular and Molecular NeuroscienceSDG 3 - Good Health and Well-beingCognitive neurosciences [UMCN 3.2]Internal medicinemental disordersmedicineAttention deficit hyperactivity disorderHumansGenetic Predisposition to Diseaseddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAssociation (psychology)Gene030304 developmental biologyFamily HealthPolymorphism Geneticbusiness.industryMood Disordersmedicine.diseaseMoodEndocrinologyMood disordersGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with Hyperactivitybiology.proteinbusiness030217 neurology & neurosurgery
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