Search results for "GOLD"
showing 10 items of 1320 documents
Polyphenols Epigallocatechin Gallate and Resveratrol, and Polyphenol-Functionalized Nanoparticles Prevent Enterovirus Infection through Clustering an…
2021
To efficiently lower virus infectivity and combat virus epidemics or pandemics, it is important to discover broadly acting antivirals. Here, we investigated two naturally occurring polyphenols, Epigallocatechin gallate (EGCG) and Resveratrol (RES), and polyphenol-functionalized nanoparticles for their antiviral efficacy. Concentrations in the low micromolar range permanently inhibited the infectivity of high doses of enteroviruses (107 PFU/mL). Sucrose gradient separation of radiolabeled viruses, dynamic light scattering, transmission electron microscopic imaging and an in-house developed real-time fluorescence assay revealed that polyphenols prevented infection mainly through clustering of…
New methodologies in transition metal catalysis. Organofluorine chemistry as the benchmark application.
2017
A lo largo de las últimas décadas, los compuestos organofluorados han encontrado numerosas aplicaciones dentro del campo de las industrias farmacéutica y agroquímica, así como en ciencias de los materiales. Dadas las singulares propiedades del átomo de flúor, éste es capaz de inducir alteraciones significativas en propiedades físico-químicas de las moléculas como lipofilia, distribución de cargas, acidez-basicidad, capacidad de formar enlaces de hidrógeno e incluso, equilibrios conformacionales. Sin embargo, la presencia de flúor en productos naturales es escasa. De hecho, la gran mayoría de las moléculas orgánicas que contienen flúor son sintéticas. De ahí el gran interés por parte de la c…
CCDC 1814033: Experimental Crystal Structure Determination
2018
Related Article: Guocheng Deng, Sami Malola, Juanzhu Yan, Yingzi Han, Peng Yuan, Chaowei Zhao, Xiting Yuan, Shuichao Lin, Zichao Tang, Boon K. Teo, Hannu Häkkinen, Nanfeng Zheng|2018|Angew.Chem.,Int.Ed.|57|3421|doi:10.1002/anie.201800327
CCDC 1814032: Experimental Crystal Structure Determination
2018
Related Article: Guocheng Deng, Sami Malola, Juanzhu Yan, Yingzi Han, Peng Yuan, Chaowei Zhao, Xiting Yuan, Shuichao Lin, Zichao Tang, Boon K. Teo, Hannu Häkkinen, Nanfeng Zheng|2018|Angew.Chem.,Int.Ed.|57|3421|doi:10.1002/anie.201800327
Experimental Constraints on the Deep Magma Feeding System at StromboliVolcano, Italy
2009
International audience; New experiments have been performed on a high-K basalt (PST-9) from Stromboli volcano, Italy, to constrain the physical conditions of golden pumice magmas at their storage level and discuss their petrogenesis. Fluid-present, H2O- and CO2-bearing, near-liquidus experiments were performed at 11508C between 100 and 400MPa and under oxidizing conditions. Glasses were analyzed by Fourier transform IR spectroscopy and their H2O and CO2 concentrations compared with those in glass inclusions.Most glass inclusions cluster near the 200MPa isobar, suggesting entrapment at a depth of ~8 km. Golden pumice magmas have viscosities of 7.9 Pa s and densities of 2.48-2.57 g/cm3. Compo…
Työkalu psyykkisten taitojen harjoitteluohjelmien optimoimiseen
2022
Mechanisms of irreversible aquaporin-10 inhibition by organogold compounds studied by combined biophysical methods and atomistic simulations
2021
Abstract The inhibition of glycerol permeation via human aquaporin-10 (hAQP10) by organometallic gold complexes has been studied by stopped-flow fluorescence spectroscopy, and its mechanism has been described using molecular modelling and atomistic simulations. The most effective hAQP10 inhibitors are cyclometalated Au(III) C^N compounds known to efficiently react with cysteine residues leading to the formation of irreversible C–S bonds. Functional assays also demonstrate the irreversibility of the binding to hAQP10 by the organometallic complexes. The obtained computational results by metadynamics show that the local arylation of Cys209 in hAQP10 by one of the gold inhibitors is mapped int…
Contre la fausse objectivité, le perspectivisme assumé ? le reportage « gonzo » de Goldin, Clark, D’Agata, Tillmans contre la photographie « document…
2019
International audience; Après 1945, un certain nombre de praticiens de la « photographie plasticienne »privilégièrent le reportage « communautaire » : une plongée, sur le long terme, au sein d’ungroupe d’individus, souvent connus, voire intimes, du photographe, qui loin de se placercomme un témoin neutre, activait le mécanisme de l’observation participante chère àl’ethnographie. Larry Clark en fournit un exemple avec la série Tulsa (1971), la premièred’une longue lignée. Nan Goldin amplifia d’autant l’inclusion de l’autrice par la pratique del’autoportrait en situation dans The Ballad of Sexual Dependency (1981-1996). Plus tard desartistes comme Antoine d’Agata ou Wolfgang Tillmans poursuiv…
Representations of the Life-giving Spring feast in Romanian iconography
2021
This article explores the development of the theme of the Life-giving Spring in Byzantine iconography. The path towards its establishment was initiated at the moment when a representation rule, an original convention was set. Thereafter, because of its diffusion in time and space, the theme became enriched by particular mentalities and sensibilities of the epochs and the communities that adopted it as a form of devotion for the Virgin Theotokos. As a result, the representations we have known so far are extremely varied. Contribution: The final purpose of this approach, as well as its contribution, is to highlight the diverse unity of the iconographic tradition and illustrate both the evolut…
CCDC 2019551: Experimental Crystal Structure Determination
2020
Related Article: Araceli Aquino, Francisco J. Caparrós, Gabriel Aullón, Jas S. Ward, Kari Rissanen, Yongsik Jung, Hyeonho Choi, João Carlos Lima, Laura Rodríguez|2020|Chem.-Eur.J.|27|1810|doi:10.1002/chem.202004051