Search results for "GRADE"

showing 10 items of 695 documents

Trans-popliteal hybrid retrograde technique for revascularization of chronic total occlusions of the superficial femoral artery.

2020

Objectives We present the technical description and preliminary results of a hybrid approach for the treatment of chronic total occlusions of superficial femoral artery in the setting of critical limb-threatening ischemia (CLTI). Methods A retrospective analysis of selected case series was performed. A trans-popliteal hybrid technique was carried out in seven limbs (six patients). Open exposure of above-the-knee popliteal artery was performed over its maximum calcification zone. After retrograde recanalization and graft-stenting of the entire superficial femoral artery, endarterectomy of the popliteal artery was performed for debulking and widening of the distal landing zone of the endopros…

Malemedicine.medical_specialtyTime Factorsmedicine.medical_treatmentCritical IllnessConstriction PathologicEndarterectomy030204 cardiovascular system & hematologyRevascularization030218 nuclear medicine & medical imaging03 medical and health sciencesBlood Vessel Prosthesis ImplantationPeripheral Arterial Disease0302 clinical medicineIschemiamedicineHumansRadiology Nuclear Medicine and imagingPopliteal ArteryVascular PatencyAgedRetrospective Studiesbusiness.industrySuperficial femoral arteryEndovascular ProceduresGeneral MedicineCritical limb ischemiaMiddle Agedmedicine.diseaseHybrid approachBlood Vessel ProsthesisFemoral ArteryTreatment OutcomeChronic DiseaseRetrograde approachSurgeryFemaleStentsRadiologymedicine.symptomCardiology and Cardiovascular MedicinebusinessCalcificationVascular
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European experience with the retrograde approach for the recanalization of coronary artery chronic total occlusions. A report on behalf of the EuroCT…

2008

Aims Recanalisation rates of coronary chronic total occlusions (CTO) remain sub-optimal. The retrograde technique was recently introduced to improve success rates. Methods and results From February 2005 until December 2007, 175 patients were treated with this technique in seven European centres by highly experienced operators: in 84 (48%) as primary strategy, in 41 (23.5%) immediately after antegrade failure and in 50 (28.5%) as a repeat procedure after previous antegrade failure. Baseline characteristics revealed a mean age 61.4 +/- 10.8 years with 29.5% and 39% of patients having diabetes and a prior history of MI, respectively. The mean occlusion duration was 50.8 months (determined in 3…

Malemedicine.medical_specialtymedicine.medical_treatmentCollateral CirculationCoronary AngiographyBalloonCoronary circulationCoronary CirculationAngioplastyOcclusionmedicineHumansMyocardial infarctionAngioplasty Balloon CoronarySeptal collaterals.Agedbusiness.industryMiddle Agedmedicine.diseaseCollateral circulationSurgeryEuropeChronic total occlusionTreatment Outcomemedicine.anatomical_structureCoronary OcclusionCoronary occlusionChronic DiseaseRetrogradeFemaleCardiology and Cardiovascular MedicinebusinessArtery
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Prospective, randomized, single-center trial comparing 3 different 10F plastic stents in malignant mid and distal bile duct strictures.

2003

Abstract Background: The aim of this study was to determine whether patency rates differ with respect to the material, design, and surface texture of 3 different plastic stents. Methods: A total of 120 patients (median age 70.5 years; interquartile range 62-78 years) with malignant mid or distal bile duct strictures, seen between March 1996 and May 1999, were prospectively randomized to receive a 10F polyurethane stent, a Teflon Tannenbaum stent, or a hydrophilic hydromer-coated polyurethane stent. The primary study outcome measure was the interval between stent insertion and the first episode of clogging (or the presence of jaundice at death without stent exchange). All 3 types of stent we…

Malemedicine.medical_specialtymedicine.medical_treatmentPolyurethanesCholestasis IntrahepaticConstriction PathologicSingle CenterProsthesis DesignRisk Assessmentlaw.inventionRandomized controlled trialCoated Materials BiocompatiblelawInterquartile rangemedicineHumansRadiology Nuclear Medicine and imagingcardiovascular diseasesProspective StudiesAgedFirst episodeCholangiopancreatography Endoscopic Retrogrademedicine.diagnostic_testEquipment Safetybusiness.industryGastroenterologyStentMiddle Agedequipment and suppliesmedicine.diseaseSurvival AnalysisEndoscopySurgeryProsthesis FailureStenosissurgical procedures operativeTreatment OutcomeBile Duct NeoplasmsBiliary tractFemaleStentsRadiologybusinessFollow-Up StudiesGastrointestinal endoscopy
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The impact of re-transurethral resection on clinical outcomes in a large multicentre cohort of patients with T1 high-grade/Grade 3 bladder cancer tre…

2015

Objectives To determine if a re-transurethral resection (TUR), in the presence or absence of muscle at the first TUR in patients with T1-high grade (HG)/Grade 3 (G3) bladder cancer, makes a difference in recurrence, progression, cancer specific (CSS) and overall survival (OS). Patients and methods In a large retrospective multicentre cohort of 2451 patients with T1-HG/G3 initially treated with bacille Calmette–Gu erin, 935 (38%) had a re-TUR. According to the presence or absence of muscle in the specimen of the primary TUR, patients were divided in four groups: group 1 (no muscle, no re-TUR), group 2 (no muscle, re-TUR), group 3 (muscle, no re-TUR) and group 4 (muscle, re-TUR). Clinical out…

Malemedicine.medical_treatment030232 urology & nephrologySettore MED/24 - Urologia0302 clinical medicineImmunologicRetrospective Studiehigh gradere-TURHazard ratioMiddle Agedmedicine.anatomical_structureAdministration IntravesicalTreatment Outcome030220 oncology & carcinogenesisUrological cancers Radboud Institute for Health Sciences [Radboudumc 15]CohortUrinary Bladder NeoplasmBCG VaccineUrologic Surgical Proceduresbladder cancerFemaleHumanReoperationmedicine.medical_specialtyrecurrenceUrologyUrologyT1G3CystectomyArticleCystectomy03 medical and health sciencesbladder cancer; high grade; progression; re-TUR; recurrence; T1G3; UrologyAdjuvants ImmunologicUrethramedicineHumansAdjuvantsT1G3; bladder cancer; high grade; progression; re-TUR; recurrenceRetrospective StudiesAgedNeoplasm StagingBladder cancerbusiness.industryCancerRetrospective cohort studymedicine.diseaseSurgerybladder cancer; high grade; progression; re-TUR; recurrence; T1G3; Adjuvants Immunologic; Aged; BCG Vaccine; Cystectomy; Female; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Reoperation; Retrospective Studies; Treatment Outcome; Urethra; Urinary Bladder Neoplasms; UrologyUrethraUrinary Bladder NeoplasmsprogressionNeoplasm GradingbusinessBCG vaccine
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The efficacy of BCG TICE and BCG Connaught in a cohort of 2,099 patients with T1G3 non–muscle-invasive bladder cancer

2016

BACKGROUND Potential differences in efficacy of different bacillus Calmette-Guerin (BCG) strains are of importance for daily practice, especially in the era of BCG shortage. OBJECTIVE To retrospectively compare the outcome with BCG Connaught and BCG TICE in a large study cohort of pT1 high-grade non-muscle-invasive bladder cancer patients. DESIGN, SETTING, AND PARTICIPANTS Individual patient data were collected for 2,451 patients with primary T1G3 tumors from 23 centers who were treated with BCG for the first time between 1990 and 2011. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS Using Cox multivariable regression and adjusting for the most important prognostic factors in this nonrandomiz…

Malemedicine.medical_treatmentIntravesical drug administration030232 urology & nephrologyKaplan-Meier EstimateBCG ConnaughtSettore MED/24 - Urologia0302 clinical medicineMaintenance therapyMedicine610 Medicine & healthhigh gradeAged 80 and overHazard ratioMiddle AgedAdministration IntravesicalTreatment OutcomeOncology030220 oncology & carcinogenesisCohortbladder cancerFemaleImmunotherapyNon muscle invasivemedicine.medical_specialtyrecurrenceUrologyBCG Connaught; BCG Tice; BCG vaccine; bladder cancer; high grade; Immunotherapy; Intravesical drug administration; progression; recurrence; T1G3; Oncology; UrologyT1G3ArticleMaintenance ChemotherapyBCG Connaught03 medical and health sciencesAdjuvants ImmunologicInternal medicineUrological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15]HumansNeoplasm InvasivenessBCG vaccineAgedNeoplasm StagingProportional Hazards ModelsRetrospective StudiesCarcinoma Transitional CellBladder cancerbusiness.industryImmunotherapy ActiveBCG TiceImmunotherapymedicine.diseaseSurgeryUrinary Bladder NeoplasmsDrug EvaluationprogressionNeoplasm GradingbusinessBCG vaccineFollow-Up StudiesBCG Connaught; BCG Tice; BCG vaccine; Immunotherapy; Intravesical drug administration; T1G3; bladder cancer; high grade; progression; recurrenceUrologic Oncology: Seminars and Original Investigations
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Preparation of three-layered porous PLA/PEG scaffold: relationship between morphology, mechanical behavior and cell permeability.

2015

Interface tissue engineering (ITE) is used to repair or regenerate interface living tissue such as for instance bone and cartilage. This kind of tissues present natural different properties from a biological and mechanical point of view. With the aim to imitating the natural gradient occurring in the bone-cartilage tissue, several technologies and methods have been proposed over recent years in order to develop polymeric functionally graded scaffolds (FGS). In this study three-layered scaffolds with a pore size gradient were developed by melt mixing polylactic acid (PLA) and two water-soluble porogen agents: sodium chloride (NaCl) and polyethylene glycol (PEG). Pore dimensions were controll…

Materials scienceBone RegenerationCell SurvivalPolymersParticulate leachingPolyestersBiomedical EngineeringBiocompatible Materials02 engineering and technologyPolyethylene glycol010402 general chemistry01 natural sciencesPermeabilityCell LinePolyethylene GlycolsBiomaterialschemistry.chemical_compoundMicePolylactic acidTissue engineeringMelt mixingPEG ratioAnimalsLactic AcidComposite materialBone regenerationPorosityCell ProliferationMechanical Phenomenachemistry.chemical_classificationTissue ScaffoldsInterface tissue engineeringPore size gradientAdhesivenessWaterFunctionally graded scaffoldPolymerPermeation021001 nanoscience & nanotechnologyBiomaterial0104 chemical sciencesSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialichemistrySolubilityMechanics of Materials0210 nano-technologyPorosityJournal of the mechanical behavior of biomedical materials
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Mechanical behavior of polylactic acid/polycaprolactone porous layered functional composites

2016

Abstract Biopolymeric porous devices exhibiting graded properties can play a crucial role in several fields, such as tissue engineering or controlled drugs release. In this context, the gradient of a specific property can be achieved by developing porous laminates composed by different types of materials. This work presents for the first time a multi-phasic porous laminate based on polycaprolactone (PCL) and polylactic acid (PLA) prepared by combining melt mixing, compression molding and particle leaching. All the materials were characterized from a morphological and a mechanical point of view. The results put into evidence the possibility to tune and to predict the mechanical properties by…

Materials scienceCompression moldingCompression moldingFunctionally graded materialCeramics and Composite02 engineering and technology010402 general chemistry01 natural sciencesControlled drugsIndustrial and Manufacturing Engineeringchemistry.chemical_compoundLayered structurePolylactic acidTissue engineeringAdhesion; Compression molding; Functionally graded materials; Layered structures; Mechanical properties; Ceramics and Composites; Mechanics of Materials; Industrial and Manufacturing Engineering; Mechanical EngineeringMechanics of MaterialComposite materialPorosityMelt mixingMechanical Engineering021001 nanoscience & nanotechnology0104 chemical scienceschemistryMechanics of MaterialsPolycaprolactoneCeramics and CompositesAdhesionLeaching (metallurgy)0210 nano-technologyMechanical propertie
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The first operating thermolytic reverse electrodialysis heat engine

2020

Abstract Thermolytic reverse electrodialysis heat engine (t-RED HE) has been recently proposed as a technology for converting low-temperature waste heat into electricity. The construction and operation of the first world lab-scale prototype unit are reported. The system consists of: (i) a reverse electrodialysis unit where, the concentration gradient between two solutions of thermolytic salts is converted into electricity and (ii) a thermally-driven regeneration unit where low-temperature heat is used to restore the initial conditions of the two feed streams. Regeneration is based on a degradation process of salts into gaseous ammonia and carbon dioxide, which can be removed almost entirely…

Materials scienceFiltration and Separation02 engineering and technology010402 general chemistry01 natural sciencesBiochemistryStripping (fiber)Low-grade heatchemistry.chemical_compoundWaste heatReversed electrodialysisOsmotic powerSalinity gradient powerGeneral Materials SciencePhysical and Theoretical ChemistryHeat engineWaste managementAmmonium bicarbonate solution021001 nanoscience & nanotechnologyWaste heat recovery Loe grade heat.0104 chemical sciencesMembranechemistryCarbon dioxideOsmotic power0210 nano-technologyConcentration gradient
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In-fiber time-resolved acousto-optics

2014

Time-resolved in-fiber acousto-optics permit the measurement of sub-ppm perturbations of the modal dispersion curves along sections of fiber exceeding 1 m long, with a spatial resolution in the order of few cm.

Materials scienceMulti-mode optical fiberbusiness.industryPhysics::OpticsPolarization-maintaining optical fiberGraded-index fiberOpticsOptoelectronicsDispersion-shifted fiberModal dispersionFiberbusinessRefractive indexPhotonic-crystal fiberLatin America Optics and Photonics Conference
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Suppression of pulse pedestal using nonlinear optical loop mirrors in grating-compensated dispersion-managed fiber transmission systems

2006

Pulse pedestal suppression by nonlinear optical loop mirrors is utilized to reduce the intersymbol interference caused by the group delay ripples of a real grating profile in dispersion-managed communication systems compensated by chirped fiber gratings.

Materials scienceMulti-mode optical fiberbusiness.industrySingle-mode optical fiberPhysics::OpticsPolarization-maintaining optical fiberGraded-index fiberFiber-optic communicationOpticsFiber Bragg gratingOptoelectronicsDispersion-shifted fiberPhysics::Atomic PhysicsbusinessPlastic optical fiberComputer Science::Information Theory2005 Pacific Rim Conference on Lasers & Electro-Optics
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