Search results for "GRI"

showing 10 items of 10209 documents

RGD-mimic polyamidoamine-montmorillonite composites with tunable stiffness as scaffolds for bone tissue-engineering applications

2017

This paper reports on the development of montmorillonite (MMT)-reinforced hydrogels, based on a peptidomimetic polyamidoamine carrying guanidine pendants (AGMA1), as substrates for the osteo-induction of osteoblast precursor cells. AGMA1 hydrogels of various degrees of crosslinking responded favourably to MMT reinforcement, giving rise to composite hydrogels with shear storage modulus G', when fully swollen in water, up to 200 kPa, i.e. 20 times higher than the virgin hydrogels and of the same order or higher than other hydrogel-based composites proposed for orthopaedic applications. This significant improvement was ascribed to the effective interpenetration between the polymer matrix and t…

AgmatinepolyamidoaminesBiomedical EngineeringMedicine (miscellaneous)montmorilloniteBone and BonesCell LineBiomaterialsMicebone regenerationMaterials Testingmental disordersPolyaminesAnimalsBone regeneration; Composite; Montmorillonite; Osteo-inductive; Polyamidoamines; Biomedical Engineering; Medicine (miscellaneous); Biomaterialscompositeosteo-inductiveQMOsteoblastsTissue EngineeringTissue Scaffoldstechnology industry and agricultureHydrogelsBentoniteRBOligopeptides
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Synthesis of 2-Prenylated Alkoxylated Benzopyrans by Horner–Wadsworth–Emmons Olefination with PPARα/γ Agonist Activity

2021

[Image: see text] We have synthesized series of 2-prenylated benzopyrans as analogues of the natural polycerasoidol, a dual PPARα/γ agonist with anti-inflammatory effects. The prenylated side chain consists of five or nine carbons with an α-alkoxy-α,β-unsaturated ester moiety. Prenylation was introduced via the Grignard reaction, followed by Johnson–Claisen rearrangement, and the α-alkoxy-α,β-unsaturated ester moiety was introduced by the Horner–Wadsworth–Emmons reaction. Synthetic derivatives showed high efficacy to activate both hPPARα and hPPARγ as dual PPARα/γ agonists. These prenylated benzopyrans emerge as lead compounds potentially useful for preventing cardiometabolic diseases.

AgonistSynthetic derivatives[CHIM.ORGA]Chemical Sciences/Organic chemistry010405 organic chemistrymedicine.drug_classStereochemistryOrganic ChemistryHorner–Wadsworth–Emmons reactionGrignard reaction01 natural sciencesBiochemistry0104 chemical sciences3. Good health010404 medicinal & biomolecular chemistrychemistry.chemical_compoundchemistryPrenylationDrug DiscoverySide chainmedicinePPARα/γ activityMoietyPrenylated benzopyransHorner-Wadsworth-Emmons reactionBenzopyransACS Medicinal Chemistry Letters
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Ansichten über die Ursachen und die wahrscheinliche Dauer der Wohlfeilheit aller Landeserzeugnisse, besonders mit Rücksicht auf Liv- und Esthland, ne…

1825

Agrarwirtschaft - BalticsLauksaimniecības ekonomikas vēsture - Baltija:SOCIAL SCIENCES::Business and economics::Economics [Research Subject Categories]Baltischen Wirtschaft - GeschichteEkonomiskais stāvoklis - BaltijaProdukthandel - BalticsBaltics economic historyProduktu tirdzniecība - BaltijaBaltijas ekonomikas vēstureAgricultural economic - Baltics
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Determinants of Italian agri-food exports in non-EU Mediterranean Partner Countries: An empirical investigation through a gravity model approach

2013

The aim of this paper is to lay emphasis on the main factors (economic, historical, structural, etc.) that affect Italian agri-food exports in the non-EU Mediterranean Partner Countries (MPCs). The authors estimate a gravity equation including some of the main variables found in the reference literature useful to highlight the main factors which influence the bilateral exchanges. The results show that the variables traditionally included in the gravity equation present the expected sign. In particular, Italian agri-food exports towards its neighbouring Mediterranean countries are positively affected by income of partner countries, colonial and historical ties, geographical proximity and the…

Agri-food exportItalySettore AGR/01 - Economia Ed Estimo RuraleEuro-mediterranean partnership
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THE ROLE OF SICILY IN THE MARITIME TRAFFIC OF AGRI-FOOD PRODUCTS IN THE MEDITERRANEAN BASIN

2011

This paper shows the results of a survey on trade flows to agri-food products among Sicily and the non-EU countries of the Union for the Mediterranean, through maritime transport. The aim of this paper is to outline the role that Sicily plays in respect of trade in agricultural products through the maritime mode considering its strategic location in the Mediterranean basin. Political reference scenario is that of the Union for the Mediterranean and EU Mediterranean Transport Policy (motorways of the sea). The work contains an analysis of the evolution of maritime trade in agri-food of Sicily, in the main ports of departure and arrival, with non-EU countries of the Union for the Mediterranea…

Agri-food tradeSettore AGR/01 - Economia Ed Estimo RuraleEuro-Mediterranean PolicyMaritime trafficSicilyAgri-food trade; Maritime traffic; Euro-Mediterranean Policy; Sicily
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AgriChain: Blockchain Syntactic and Semantic Validation for Reducing Information Asymmetry In Agri-Food

2022

Information asymmetry affects the actors of all the segments of the agri-food supply chain and can arise many problems in the market along the production chain. Transactions of agri-food products are asymmetric because suppliers and buyers have different levels of knowledge on the provenance, value, quality, and freshness of food. Collusive relations among the agri-food chain actors, especially between controllers companies and controlled ones, can cause market failures as they influence customers’ purchase decisions and severe health accidents when food safety is compromised. This paper proposes using blockchain technology to combat information asymmetry and collusive relations. In additio…

Agri-food economy blockchain smart contract information asymmetry validation
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Quality Markers and Consumer Communication Strategies: Empirical Evidence in the 'Very Fresh' Sector in Italy

2008

Quality is a key factor when consumers choose agri-food products, but at the same time is difficult for them to assess. On the demand side, consumers require protection measures, and on the supply side, efficient communications need to be available to all operators, including those who cannot afford to supply their own. In this context, quality markers such as logos, brands and indications or denominations that distinguish a product from its competitors can be a strategic way of transmitting information, especially for firms which cannot afford resources for communications or their own brand name. This research analyses and assesses the role of brands and territorial markers (PDO, PGI) in e…

Agribusiness Agricultural and Food Policy Food Consumption/Nutrition/Food Safety
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Compte rendu d'ouvrage - Les mondes du vin. Ethnologie des vignerons d'Arbois.

2005

International audience

Agribusiness[SHS.SOCIO]Humanities and Social Sciences/Sociology[SHS.SOCIO] Humanities and Social Sciences/Sociology[SHS.HIST] Humanities and Social Sciences/History[SHS.ECO] Humanities and Social Sciences/Economics and Finance[SHS.HIST]Humanities and Social Sciences/History[SHS.ECO]Humanities and Social Sciences/Economics and FinanceComputingMilieux_MISCELLANEOUS
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Influenza di alcune tecniche agronomiche sulla produzione di seme di sulla (Hedysarum coronarium L.) allevata con metodo biologico in ambiente medite…

2008

Agricoltura biologica
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Effetti della consociazione temporanea con favino sulla produttività e qualità del frumento duro in sistemi biologici.

2009

Agricoltura biologica Triticum durum nutrizione azotataSettore AGR/02 - Agronomia E Coltivazioni Erbacee
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