Search results for "GRI"
showing 10 items of 10209 documents
Ocean-scale connectivity and life cycle reconstruction in a deep-sea fish
2014
Author's version of an article in the journal: Canadian Journal of Fisheries and Aquatic Sciences. Also available from the publisher at: http://dx.doi.org/10.1139/cjfas-2013-0343 As human exploration and harvesting moves to the high seas, ecological understanding of the deep sea has become a priority, especially in those commercially exploited species whose life cycle, habitat use, and demographic structure remain poorly understood. Here we combine otolith trace element and stable isotope analyses with microsatellite data to investigate population structure and connectivity in the migratory deep-sea black scabbardfish (Aphanopus carbo), sampled along a latitudinal gradient spanning much of …
A la búsqueda de la armonía cívica perdida: Eros, Afrodita y la reformulación dramática en las tragedias tardías de Sófocles
2013
En las últimas tragedias de Sófocles hay un replanteamiento de sus posiciones, perceptible en la reconfiguración de sus carácteres y en su relación con los dioses. En Antígona y Traquinias, obras tempranas, a través de sus coros vemos las diferentes formas de concreción de Eros-Afrodita. En Edipo en Colono se sirve otra vez de Afrodita, pero en una forma y sentido singulares.
Efficacy and safety of bempedoic acid for the treatment of hypercholesterolemia: A systematic review and meta-analysis
2020
Background Bempedoic acid is a first-in-class lipid-lowering drug recommended by guidelines for the treatment of hypercholesterolemia. Our objective was to estimate its average effect on plasma lipids in humans and its safety profile. Methods and findings We carried out a systematic review and meta-analysis of phase II and III randomized controlled trials on bempedoic acid (PROSPERO: CRD42019129687). PubMed (Medline), Scopus, Google Scholar, and Web of Science databases were searched, with no language restriction, from inception to 5 August 2019. We included 10 RCTs (n = 3,788) comprising 26 arms (active arm [n = 2,460]; control arm [n = 1,328]). Effect sizes for changes in lipids and high-…
Influence of cultivar and concentration of selected phenolic constituents on the in vitro chemiopreventive potential of olive oil extracts.
2011
One of the main olive oil phenolic compounds, hydroxytyrosol (3,4-DHPEA), exerts in vitro chemopreventive activities (antiproliferative and pro-apoptotic) on tumor cells through the accumulation of H2O2 in the culture medium. However, the phenol composition of virgin olive oil is complex, and 3,4-DHPEA is present at low concentrations when compared to other secoiridoids. In this study, the in vitro chemopreventive activities of complex virgin olive oil phenolic extracts (VOO-PE, derived from the four Italian cultivars Nocellara del Belice, Coratina, Ogliarola, and Taggiasca) were compared to each other and related to the amount of the single phenolic constituents. A great chemopreventive po…
The importance of pattern similarity between Müllerian mimics in predator avoidance learning
2004
Müllerian mimicry, where unpalatable prey share common warning patterns, has long fascinated evolutionary biologists. It is commonly assumed that Müllerian mimics benefit by sharing the costs of predator education, thus reducing per capita mortality, although there has been no direct test of this assumption. Here, we specifically measure the selection pressure exerted by avian predators on unpalatable prey with different degrees of visual similarity in their warning patterns. Using wild-caught birds foraging on novel patterned prey in the laboratory, we unexpectedly found that pattern similarity did not increase the speed of avoidance learning, and even dissimilar mimics shared the educatio…
Computation of a few smallest eigenvalues of elliptic operators using fast elliptic solvers
2001
The computation of a few smallest eigenvalues of generalized algebraic eigenvalue problems is studied. The considered problems are obtained by discretizing self-adjoint second-order elliptic partial differential eigenvalue problems in two- or three-dimensional domains. The standard Lanczos algorithm with the complete orthogonalization is used to compute some eigenvalues of the inverted eigenvalue problem. Under suitable assumptions, the number of Lanczos iterations is shown to be independent of the problem size. The arising linear problems are solved using some standard fast elliptic solver. Numerical experiments demonstrate that the inverted problem is much easier to solve with the Lanczos…
La articulación local-global de sistemas territoriales de producción y de innovación
2009
RESUMEN Frente a la controversia al respecto en economía regional, este artículo defiende la complementariedad entre la innovación regional y global en los sistemas de producción y de innovación (SPI), como clave de la articulación (dinámica, secuencial y recursiva) local-global. Para ello se introduce el concepto de nudos tecnológicos localizados (NUTELO). Los NUTELO son los eslabones de la cadena de valor donde convergen la especificidad de los SPI y el ámbito de mayor densidad de sus relaciones externas. Un esbozo de marco evolucionista se apoya en el estudio de la articulación de la citricultura valenciana con la citricultura catalana y argentino-uruguaya. ABSTRACT The local or global c…
Functional Fibronectin Adsorption on Aptamer-Doped Chitosan Modulates Cell Morphology by Integrin-Mediated Pathway.
2019
A decisive step in cell-biomaterial interaction is represented by the adsorption of proteins at the interface, whose fine control may be useful to trigger proper cell response. To this purpose, we can selectively control protein adsorption on biomaterials by means of aptamers. Aptamers selected to recognize fibronectin dramatically enhance chitosan ability to promote cell proliferation and adhesion, but the underlying biological mechanism remains unknown. We supposed that aptamers contributed to ameliorate the adsorption of fibronectin in an advantageous geometrical conformation for cells, thus regulating their morphology by the proper activation of the integrin-mediated pathway. We investi…
Sākumskolas skolēnu pašregulācijas prasmju sekmēšana klases stundās.
2022
Darba autore: Sanita Vītiņa Bakalaura darba temats: Sākumskolas skolēnu pašregulācijas prasmju sekmēšana klases stundās. Mērķis: Teorētiski analizēt un praktiski pārbaudīt kā klases stundās sākumskolas skolēniem sekmējamas pašregulācijas prasmes. Darba pirmajā teorētiskajā daļā tiek pētītas un analizētas dažādu pedagoģijas un psiholoģijas autoru atziņas par pašregulācijas prasmju jēdzienu, kā arī tā saistību ar sociāli emocionālo mācīšanos. Papildus tiek analizēts sākumskolas skolēnu raksturojums darba tēmas ietvaros. Darba otrajā nodaļā tiek analizētas klases stundas un tiek pētīts, kā klases stundu ietvaros ir iespējams sekmēt skolēnu pašregulācijas prasmes, izmantojot apzinātības vingrin…
Toward sustainable environmental quality : Priority research questions for Europe
2018
P.J. Van den Brink et al.