Search results for "GRI"

showing 10 items of 10209 documents

Biomechanische Überlegungen über Stoßkräfte und Fußstabilität beim Laufen

1993

The interaction between "man-shoe and surface" is presented as a model to discuss the complexity of human locomotion. Only if the physiological system "man" interacts positively with the physical requirements of shoe and surface quality running will become effective and economical. Especially during the early ground contact phase the hardness of the shoe construction determines the height of the vertical impact load. These adaptations have consequences in the emg amplitudes during the stretch activation phase of the contact. Comparing various jogging shoes with altered construction properties it can be shown that the "hardness" of the shoe material is well adapted by the variation in the em…

musculoskeletal diseasesFoot (prosody)Computer sciencebusiness.industrytechnology industry and agricultureEMG amplitudeStructural engineeringFlexor musclesStability (probability)Biomechanical Phenomenabody regionsGround contactotorhinolaryngologic diseasesOrthopedics and Sports MedicineRange of motionbusinessHuman locomotionSportverletzung · Sportschaden
researchProduct

Targeting of the transcription factor STAT4 by antisense phosphorothioate oligonucleotides suppresses collagen-induced arthritis

2007

Abstract The transcription factor STAT4 mediates signals of various proinflammatory cytokines, such as IL-12, IL-15, and IL-23, that initiate and stabilize Th1 cytokine production. Although Th1 cytokine production has been suggested to play a major pathogenic role in rheumatoid arthritis, the role of STAT4 in this disease is poorly understood. In this study, we demonstrate a key functional role of STAT4 in murine collagen-induced arthritis (CIA). In initial studies we found that STAT4 expression is strongly induced in CD4+ T cells and to a lesser extent in CD11b+ APCs during CIA. To analyze the role of STAT4 for arthritis manifestation, we next investigated the outcome of interfering with S…

musculoskeletal diseasesImmunologyAntigen-Presenting CellsCodon InitiatorArthritisBiologyProinflammatory cytokineArthritis RheumatoidPathogenesisMiceimmune system diseasesmedicineAnimalsImmunology and Allergyskin and connective tissue diseasesSTAT4Cells CulturedMice KnockoutMice Inbred BALB CCD11b Antigenhemic and immune systemsOligonucleotides AntisenseSTAT4 Transcription FactorTh1 CellsThionucleotidesmedicine.diseaseArthritis ExperimentalIntegrin alpha MRheumatoid arthritisImmunologybiology.proteinExperimental pathologyTumor necrosis factor alpha
researchProduct

Residual Stress Effects on Fatigue Crack Growth in Ti-6Al-4V Friction Stir Welds

2008

Recent studies have illustrated a predominant role of the residual stress on the fatigue crack growth in friction stir welded joints. In this study, the role of the residual stress on the propagation of fatigue cracks orthogonal to the weld direction in a friction stir welded Ti-6Al-4V joint was investigated. A numerical prediction of the fatigue crack growth rate in the presence of the residual stresses was carried out using AFGROW software; reasonable correspondence between the predictions and the experimental results were observed when the effects of residual stress were included in the simulation.

musculoskeletal diseasesMaterials scienceMechanical EngineeringMetallurgytechnology industry and agricultureAFGROWFracture mechanicsrespiratory systemParis' lawCrack closureMechanics of MaterialsResidual stressFriction stir weldingGeneral Materials ScienceFriction weldingComposite materialStress concentration
researchProduct

Traction test of temporary dental cements

2017

Background Classic self-curing temporary cements obstruct the translucence of provisional restorations. New dual-cure esthetic temporary cements need investigation and comparison with classic cements to ensure that they are equally retentive and provide adequate translucence. The objective is to analyze by means of traction testing in a in vitro study the retention of five temporary cements. Material and methods Ten molars were prepared and ten provisional resin restorations were fabricated using CAD-CAM technology (n=10). Five temporary cements were selected: self-curing temporary cements, Dycal (D), Temp Bond (TB), Temp Bond Non Eugenol (TBNE); dual-curing esthetic cements Temp Bond Clear…

musculoskeletal diseasesMolarMaterials sciencemedicine.medical_treatmentResin restorationsDentistry02 engineering and technology03 medical and health sciences0302 clinical medicineDental cementmedicineIn vitro studyGeneral DentistryProsthetic Dentistrybusiness.industryResearchtechnology industry and agriculture030206 dentistryTraction (orthopedics):CIENCIAS MÉDICAS [UNESCO]equipment and supplies021001 nanoscience & nanotechnologysurgical procedures operativeUNESCO::CIENCIAS MÉDICAS0210 nano-technologybusinessJournal of Clinical and Experimental Dentistry
researchProduct

Bioactividad del polimetilmetacrilato (cemento óseo) modificado

1988

The polymethylmetacrylate bone cement reaction in clinical practice is conditioned in part by its biological activity and ageing An in vivo and in vitro experimental study was conducted to elucidate the possible implications of some bone cements mineral additives on bioactivity behaviour. ' Some substances (as quartz and wollastonite) can develop bioactivity phenomena when added to PMMA cement and may enhance its biological compatibility.

musculoskeletal diseasesUNESCO::CIENCIAS MÉDICAStechnology industry and agriculture:CIENCIAS MÉDICAS [UNESCO]equipment and supplies
researchProduct

Ritz Solution for Transient Analysis of Variable-Stiffness Shell Structures

2020

The dynamic response of thin-walled structures is driven by mass and stiffness distribution. As such, variable-stiffness (VS) composites offer opportunities to tune structural dynamic responses. To this extent, efficient analysis tools become increasingly important for structural analysis and design purposes. In this work, an efficient and versatile Ritz method for free vibrations and linear transient analysis of VS doubly curved shell structures is presented. VS shell structures are modeled as an assembly of shell-like domains. The shell kinematics is based on the first-order shear deformation theory, and no further assumption is made on the shallowness or on the thinness of the structure.…

musculoskeletal diseasesanimal structuresMaterials scienceDistribution (number theory)Shell (structure)Aerospace Engineeringmacromolecular substances02 engineering and technologyVariable angle tow composites Composite shells Ritz method01 natural sciencesSpherical shellData preparation010305 fluids & plasmasComputer Science::RoboticsPhysics::Fluid Dynamics0203 mechanical engineering0103 physical sciencesmedicineComposite material020301 aerospace & aeronauticsVariable stiffnesstechnology industry and agricultureStiffnessequipment and suppliesTransient analysisFinite element methodmedicine.symptomAIAA Journal
researchProduct

Stiffness and Reinforcement Effect of electrical Resistance Strain Gauges

2007

:  The increasing use of low-modulus materials, on which the reinforcement effect of the electrical resistance strain gauge is not negligible, has re-opened the research interest into this issue. This study deals with the evaluation of stiffness, and of the strain gauge Young's modulus involved in the estimation of both the global and the local reinforcement effect; the relationship between the strain gauge stiffness and the local reinforcement effect is also analysed. In particular, the experimental technique used to determine the stiffness of some commercial strain gauges is described. The results show that the strain gauge stiffness alone does not permit an accurate evaluation of the loc…

musculoskeletal diseasesanimal structuresMaterials sciencebusiness.industryMechanical Engineeringtechnology industry and agricultureModulusStiffnessStructural engineeringequipment and suppliesmusculoskeletal systemexperimental mechanicreinforcement effectSettore ING-IND/14 - Progettazione Meccanica E Costruzione Di MacchineElectrical resistance and conductancestrain gaugesMechanics of MaterialsmedicineSettore ING-IND/12 - Misure Meccaniche E Termichemedicine.symptomComposite materialReinforcementbusinessStrain gaugestiffne
researchProduct

Improving the cementation of the tibial component in knee arthroplasty : a study of four techniques in the cadaver.

2021

Aims The main objective of this study is to analyze the penetration of bone cement in four different full cementation techniques of the tibial tray. Methods In order to determine the best tibial tray cementation technique, we applied cement to 40 cryopreserved donor tibiae by four different techniques: 1) double-layer cementation of the tibial component and tibial bone with bone restrictor; 2) metallic cementation of the tibial component without bone restrictor; 3) bone cementation of the tibia with bone restrictor; and 4) superficial bone cementation of the tibia and metallic keel cementation of the tibial component without bone restrictor. We performed CT exams of all 40 subjects, and mea…

musculoskeletal diseasesbone plugsTotal Knee Arthroplastymedicine.medical_treatmentepiphysistibial boneMetaphysisDiseases of the musculoskeletal systemknee arthroplasty03 medical and health sciences0302 clinical medicineCadaverMedicineOrthopedics and Sports MedicineKnee030212 general & internal medicineTibial boneFemoral componentOral Tranexamic AcidTotal Blood LossmetaphysisOrthodontics030222 orthopedicsbone cementtourniquetsbusiness.industryTibial traytibial tray’stechnology industry and agricultureCementation techniquesBone cementCementation (geology)musculoskeletal systemequipment and suppliesArthroplastyt-testmedicine.anatomical_structuresurgical procedures operativetibial componentsRC925-935Randomized Controlled TrialSurgerybusinessBonejoint research
researchProduct

Novel Digital Technique to Quantify the Area and Volume of Cement Remaining and Enamel Removed after Fixed Multibracket Appliance Therapy Debonding: …

2020

The aim of this study was to construct a novel, repeatable, reproducible, and accurate measurement protocol for the area and volume of the remaining cement after removal of fixed multibracket appliances, the area and volume of remaining cement after cement removal, the area and volume of enamel removed after cement removal, and the volume of cement used to adhere fixed multibracket appliances. A total of 30 brackets were cemented and removed with over 30 extracted teeth embedded into three experimental models of epoxy resin. The models were scanned before and after bracket placement, bracket debonding, and polishing the remaining cement. The brackets were submitted to micro-computed tomogra…

musculoskeletal diseaseslcsh:MedicineCementos dentales.Orthodontics.Article03 medical and health sciences0302 clinical medicineDientes - Anomalías y malformaciones - Tratamiento.Teeth - Abnormalities - Treatment.Dental cement0502 economics and businessOrtodoncia.In vitro studyMedicineMateriales dentales.Dental therapeutics - Equipment and supplies.CementTerapéutica dental - Aparatos y material.ReproducibilityDental enamel.Enamel paintDental cements.business.industryenamel removedlcsh:R05 social sciencesBrackettechnology industry and agriculturegeomorphometryalignment030206 dentistryGeneral MedicineRepeatabilityequipment and suppliesEsmalte dental.surgical procedures operativecement remainingvisual_artdigital impressionvisual_art.visual_art_medium050211 marketingDental materials.businessorthodonticsBiomedical engineeringVolume (compression)Journal of Clinical Medicine
researchProduct

CMC is more than a measure of corticospinal tract integrity in acute stroke patients

2021

In healthy subjects, motor cortex activity and electromyographic (EMG) signals from contracting contralateral muscle show coherence in the beta (15-30 Hz) range. Corticomuscular coherence (CMC) is considered a sign of functional coupling between muscle and brain. Based on prior studies, CMC is altered in stroke, but functional significance of this finding has remained unclear. Here, we examined CMC in acute stroke patients and correlated the results with clinical outcome measures and corticospinal tract (CST) integrity estimated with diffusion tensor imaging (DTI). During isometric contraction of the extensor carpi radialis muscle, EMG and magnetoencephalographic oscillatory signals were re…

musculoskeletal diseasesmagnetoencephalographyafferent inputaivoinfarktiMEGtechnology industry and agriculturemacromolecular substancesmusculoskeletal systemstrokecorticospinal tract integritybody regionshermo-lihastoimintaaivokuorimotor cortexcorticomuscular coherencemotoriikka
researchProduct