Search results for "GUIDANCE"
showing 10 items of 157 documents
Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
2021
Background The European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (FHSC) global registry provides a platform for the global surveillance of familial hypercholesterolaemia through harmonisation and pooling of multinational data. In this study, we aimed to characterise the adult population with heterozygous familial hypercholesterolaemia and described how it is detected and managed globally. Methods Using FHSC global registry data, we did a cross-sectional assessment of adults (aged 18 years or older) with a clinical or genetic diagnosis of probable or definite heterozygous familial hypercholesterolaemia at the time they were entered into the registries. Dat…
Regulatory and academic studies to derive reference values for human health: The case of bisphenol S
2022
We would like to thank the HBM4EU team including Petra Apel (UBA), Matthieu Meslin and Christophe Rousselle (Anses) for their scientific contribution, as well as the ANSES Working Group on endocrine disruption, and its scientific Anses coordinators François Pouzaud and Sandrine Charles.; International audience; The close structural analogy of bisphenol (BP) S with BPA, a recognized endocrine-disrupting chemical and a substance of very high concern in the European Union, highlights the need to assess the extent of similarities between the two compounds and carefully scrutinize BPS potential toxicity for human health. This analysis aimed to investigate human health toxicity data regarding BPS…
Transcranial magnetic resonance-guided focused ultrasound surgery at 1.5T: a technical note.
2019
Magnetic resonance-guided focused ultrasound is one of the emerging non-invasive technologies offering both image guidance and thermal monitoring. In recent years transcranial application of this technology is starting to impact heavily the neuroscience field. We present here the imaging protocol and the technological methods successfully used with a transcranial magnetic resonance-guided focused ultrasound system certified for clinical treatments of functional neurological disorders, integrated for the first time with a 1.5T magnetic resonance scanner. Compared to the body radiofrequency coil (the one commonly used with transcranial magnetic resonance-guided focused ultrasound system integ…
Diverse histories, common ground and a shared future:the education of career guidance and counselling professionals in the Nordic countries
2019
The development of education programmes in career guidance and counseling (CGC) has followed different paths among the various Nordic countries. Ten CGC programmes in Denmark, Finland, Greenland, Iceland, Norway and Sweden were evaluated against the NICE curricular model. The results show that all NICE core competences are represented in the curricula. However, there is greater focus in some programmes on developing competences for individual career guidance, than on developing competences for working at organisational and societal levels. Implications for the cooperation and professionalisation of CGC within the Nordic countries are discussed as well as limitations of the NICE model. Keywo…
Current Guidance during the orientation in career counseling
2010
Abstract Counseling is a complex process encompassing a large wide range of interventions that requires specialized training. Success counseling is provided by the active involvement and responsibility of both parties (counselor and counseled people) in making a genuine alliance based on mutual respect and trust. The concept of career guidance is covered the widest range of activities, take information and evaluation, counseling and education to career and becomes the “umbrella concept” for activities in this area.
Una scuola che orienta nella formazione del progetto di vita
2019
The vocational training project is studied, within the wider life project, towards the end of adolescence. It is identified in the absence of planning, the main cause of the high number of young people who do not study, do not work and are not trained. To encourage a vocational training project by the students, teachers, in carrying out educational activities, should always bear in mind the educational and cultural profile of the young people at the end of high school.
La scrittura espressiva: fondamenti teorici, applicazioni e nuove prospettive di ricerca
2014
Raccontare le esperienze traumatiche e stressanti della propria vita, cercando di chiarirne i significati personali, serve non solo ad oggettivare i propri vissuti ed a conoscersi meglio, ma può anche migliorare le condizioni di salute psico-fisica, l’efficienza personale e modificare in senso positivo il modo di pensare, gli atteggiamenti, i comportamenti e le relazioni interpersonali. James Pennebaker ha inaugurato un filone di studi sperimentali volti a chiarire gli effetti della scrittura espressiva e i meccanismi psicofisiologici che si innescano quando traumi ed esperienze stressanti sono verbalizzati. Il pensiero narrativo è la prospettiva che dà fondamento teorico a tale metodo di r…
Bloqueo interescalénico guiado por ecografía en un paciente con alteraciones anatómicas de la región supraclavicular secundarias a radioterapia y cir…
2011
Regional blocks can be difficult in surgical patients with certain superficial anatomical abnormalities. Such blocks may be possible, however, under ultrasound guidance. We report a case in which a man with a fractured right humerus required an ultrasound-guided interscalene brachial plexus block. Secondary to radiotherapy, the patient had right cervical and facial abnormalities that had altered the location of external anatomical landmarks. We describe the approach used to insert the catheter and the exploration of the region by ultrasound. Nerve stimulation was not used to avoid painful contractions. Analgesia was excellent during surgery and over the following 24 hours.
Dscam1 Is Required for Normal Dendrite Growth and Branching But Not for Dendritic Spacing in Drosophila Motoneurons
2014
Down syndrome cell adhesion molecule, Dscam, serves diverse neurodevelopmental functions, including axon guidance and synaptic adhesion, as well as self-recognition and self-avoidance, depending on the neuron type, brain region, or species under investigation. InDrosophila, the extensive molecular diversity that results from alternative splicing of Dscam1 into >38,000 isoforms provides neurons with a unique molecular code for self-recognition in the nervous system. Each neuron produces only a small subset of Dscam1 isoforms, and distinct Dscam1 isoforms mediate homophilic interactions, which in turn, result in repulsion and even spacing of self-processes, while allowing contact with neig…
Neuronal polarization is impaired in mice lacking RhoE expression
2012
J. Neurochem. (2012) 121, 903–914. Abstract Proper development of neuronal networks relies on the polarization of the neurons, thus the establishment of two compartments, axons and dendrites, whose formation depends on cytoskeletal rearrangements. Rnd proteins are regulators of actin organization and they are important players in several aspects of brain development as neurite formation, axon guidance and neuron migration. We have recently demonstrated that mice lacking RhoE/Rnd3 expression die shortly after birth and have neuromotor impairment and neuromuscular alterations, indicating an abnormal development of the nervous system. In this study, we have further investigated the specific ro…