Search results for "GWA"

Time-resolving Analysis of Cryotropic Gelation of Water/Poly(Vinyl Alcohol) Solutions via Small Angle Neutron Scattering

2007

The structural transformations occurring in initially homogeneous aqueous solutions of poly(vinyl alcohol) (PVA) through application of freezing (-13 degrees C) and thawing (20 degrees C) cycles is investigated by time resolving small-angle neutron scattering (SANS). These measurements indicate that formation of gels of complex hierarchical structure arises from occurrence of different elementary processes, involving different length and time scales. The fastest process that could be detected by our measurements during the first cryotropic treatment consists of the crystallization of the solvent. However, solvent crystallization is incomplete, and an unfrozen liquid microphase more concentr…

2021

Abstract. The strong reduction of air traffic during the COVID-19 pandemic provides a unique test case for the relationship between air traffic density, contrails, and their radiative forcing of climate change. Here, air traffic and contrail cirrus changes are quantified for a European domain for March to August 2020 and compared to the same period in 2019. Traffic data show a 72 % reduction in flight distance compared with 2019. This paper investigates the induced contrail changes in a model study. The contrail model results depend on various methodological details as discussed in parameter studies. In the reference case, the reduced traffic caused a reduction in contrail length. The reduc…

Definition and predictability of an OLR based West African monsoon onset

2008

The monsoon onset is documented in terms of latitudinal shift of deep convection areas within the ITCZ using an interpolated version of the National Oceanic and Atmospheric Administration (NOAA) Outgoing Longwave Radiation (OLR) at a 5-day time-step over West Africa for the period 1979–2004. Signals in moist convection derived from OLR values lower than 180 W/m2 allow better determination of onset dates (ODs) than the use of other thresholds or of the raw values of OLR. Such ODs are defined without any time filtering or spatial averaging along the meridional plane. They are also significantly correlated with ODs based on other datasets such as the CMAP and Global Precipitation Climatology P…

Genetically elevated gamma-glutamyltransferase and Alzheimer's disease

2018

Observational epidemiological evidence supports a linear and independent association between serum gamma-glutamyltransferase (GGT) concentrations and the risk of Alzheimer's disease (AD). However, the causality of this association has not been previously investigated. We sought to assess the causal nature of this association using a Mendelian randomization (MR) approach. Using inverse-variance weighted MR analysis, we assessed the association between GGT and AD using summary statistics for single nucleotide polymorphism (SNP)-AD associations obtained from the International Genomics of Alzheimer's Project of 17,008 individuals with AD and 37,154 controls. We used 26 SNPs significantly associ…

Słownik gwar śląskich

2016

Słownik gwar Śląskich [Dictionary of Silesian Dialects] contains vocabulary from all of the region’s dialects. The dictionary is based on rich lexical materiał, which has been collected sińce the 1950s. The first volume was published in 2000, sińce then thirteen volumes have appeared (containing vocabulary starting with letters from A to J). The core of the materiał is constituted by 20th-eentury vocabulary; however, there are many components of older origin. The aim of the editorial board is the archiving of the Silesian glossary and the structure of the dictionary is subordinated to this purpose. The article presents the structure of the entries, the rules of semantic description of the l…

Genetics of exceptional longevity: possible role of GM allotypes

2018

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Giuseppe Samonà e la “spina dorsale” di Gibellina Nuova

2020

Nel 1970 Giuseppe Samonà coordina il gruppo di progettazione formato da Vittorio Gregotti, Gianni Pirrone e Alberto Samonà per il Progetto del Centro civico, commerciale e culturale di Gibellina Nuova. Del piano è realizzato il municipio e poi, rielaborato e in altro luogo, il teatro. I monumenti, fondati su un asse pedonale in quota connesso a un suolo artificiale articolato, esprimono l’unità architettura – urbanistica e anticipano, per certi versi, una riflessione successiva del Direttore dello IUAV sulla dialettica fra urbano e rurale.

Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Intera…

2019

Although, for decades, increased serum bilirubin concentrations were considered a threatening sign of underlying liver disease and had been associated with neonatal jaundice, data from recent years show that bilirubin is a powerful antioxidant and suggest that slightly increased serum bilirubin concentrations are protective against oxidative stress-related diseases, such as cardiovascular diseases. Therefore, a better understanding of the gene-diet interactions in determining serum bilirubin concentrations is needed. None of the previous genome-wide association studies (GWAS) on bilirubin concentrations has been stratified by sex. Therefore, considering the increasing interest in incorporat…

Visa genoma asociācija identificē ģenētiskos marķierus, kas saistīti ar hipofīzes adenomas risku un fenotipu

2019

Visa genoma asociācijas pētījumi(GWAS) ir pētījumu metode noteikta klīniskā stāvokļa ģenētiskā cēloņa noskaidrošanai, izmantojot genotipēšanas mikromasīvus un SNP nelīdzsvarotās saistības principu. Hipofīzes adenomas(HA) ir nemetastazējoši audzēji ar dažādu molekulāro izcelsmi. Līdz šim zināmas vairākas somatiskas mutācijas (GNAS, MEN1, USP8, GPR101), kas asociētas ar noteiktu HA klīnisko tipu klātbūtni, kā arī veikti kandidātgēnu pētījumi HA ģenētisko cēloņu noteikšanai. Līdz šim pasaulē veikts tikai viens GWAS pētījums, lai konstatētu ar HA tumoroģenēzi asociētos SNP Ķīnas Han populācijā. Šajā darbā izmantoja 233 HA un 468 kontroles indivīdu genotipus, tika noteikti ar palielinātu hipofīz…

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

2013

Author version made available in accordance with the publisher's policy.