Search results for "Gate"

Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue.

2006

Conjugated linoleic acids (CLAs) are conjugated dienoic isomers of linoleic acid. Many people supplement their diets with CLAs to attempt weight loss, and the trans-10,cis-12 isomer (t10,c12-CLA) of CLA reduces adiposity in animal models and humans. However, CLA treatment in mice causes insulin resistance that has been attributed to the lipoatrophic state, which is associated with hyperinsulinemia and hepatic steatosis. Here, we investigated the effect of t10,c12-CLA on adipose tissue inflammation, another factor promoting insulin resistance. We confirmed that t10,c12-CLA daily gavage performed in mice reduces white adipose tissue (WAT) mass and adiponectin and leptin serum levels and provo…

Maximum Likelihood Estimation and non-linear least squares fitting with Levenberg-Marquardt Algorithm implementation in FPGA devices for high resolut…

2012

This work compares two possible solutions to achieve a higher resolution in a hodoscope based on Plastic Scintillating Fibers (PSF) by obtaining the point of maximum incidence of the radioactive beam. The two fitting algorithms proposed have been tested and implemented in Field Programmable Gate Array (FPGA) devices. On one hand, a probabilistic model based on the Maximum Likelihood Estimation (MLE) and on the other hand, non-linear least-squares fit with the Levenberg-Marquardt Algorithm (LMA).

Investigating on the environmental sustainability of organic animal products? The case of organic eggs

2020

Abstract The organic farming of laying hens is experiencing a growing trend in Italy, following an increase in consumer demand for organic eggs. The present study aimed to investigate the environmental performance of organic egg production for the first time in the Italian context. To this end, the Life Cycle Assessment (LCA) of organic egg production in a farm rearing laying hens located in Northern Italy was performed. The analysis was carried out in a cradle to farm gate perspective, with 1 kg of eggs selected as functional unit. Primary data relating to animal performances and resources consumed was collected on site, and subsequently integrated with secondary data, including estimates …

A Nonlinear Primal-Dual Method for Total Variation-Based Image Restoration

1999

We present a new method for solving total variation (TV) minimization problems in image restoration. The main idea is to remove some of the singularity caused by the nondifferentiability of the quantity $|\nabla u|$ in the definition of the TV-norm before we apply a linearization technique such as Newton's method. This is accomplished by introducing an additional variable for the flux quantity appearing in the gradient of the objective function, which can be interpreted as the normal vector to the level sets of the image u. Our method can be viewed as a primal-dual method as proposed by Conn and Overton [ A Primal-Dual Interior Point Method for Minimizing a Sum of Euclidean Norms, preprint,…

Mitochondrial respiration on rumenic and linoleic acids

2001

Rumenic acid ( cis -9, trans -11-C 18:2 ) represents approx. 80% of conjugated linoleic acid (CLA) in dairy products. CLA has been shown to exert beneficial effects on health, but little work has been devoted to the ability to oxidize CLA isomers and the role of these isomers in the modulation of β-oxidation flux. In the present study, respiration on rumenic acid was compared with that on linoleic acid ( cis -9, cis -12-C 18:2 ) with the use of rat liver mitochondria. In state-3, respiration was decreased by half with rumenic acid in comparison with linoleic acid. In the uncoupled state, respiration on CLA remained 30% lower. The lower ability to oxidize CLA was investigated through charact…

The amide of galacturonic acid with lysine as an immunodominant component of the lipopolysaccharide core region from Proteus penneri 42 strain

2014

Most Proteus lipopolysaccharides (LPSs) contain uronic acids or their amides with different amino acids, which together with other negatively charged components account for the acidic character of such LPS molecules. Previous studies have shown the significance of an amide of galacturonic acid with lysine [D-GalA(L-Lys)] for serological specificity of O-antigens from few P. mirabilis strains. In this work, the immunodominant role of GalALys was indicated for the P. penneri 42 LPS core region. The studies also showed the serological identity of core oligosaccharides from P. penneri 42 (O71), P. mirabilis 51/57 (O28) and R14/S1959 strains. from P. penneri 42 (O71), P. mirabilis 51/57 (O28) an…

Differentiability of Lipschitz maps

2010

Trimda un identitāte Agates Nesaules romānos

2020

Šis pētnieciskais darbs aplūko identitātes un trimdas jēdzienus Agates Nesaules romānos 'Sieviete dzintarā' un 'Zudušie saulgrieži'. Pētnieciskā darba mērķis ir aplūkot veidus, kādos Agate Nesaule pauž identitātes un trimdas jēdzienus attiecībā uz Amerikas latviešu biedrību vēsturi un piedzīvoto pēc 1944. gada. Pētījums tika veikts, izmantojot literārās analīzes metodi trimdas literatūras studiju kontekstā. Agates Nesaules romāni atspoguļo savstarpējo saikni starp trimdu, atmiņu un identitāti, parādot, ka pārvietošanās trauma ir trimdinieku neatņemama sastāvdaļa. Romānos atklātie trimdas piedzīvojumi rāda pēckara latviešu trimdinieku integra…

Novel two-step synthesis of gold nanoparticles capped with bile acid conjugates

2008

Bile acids and their conjugates are physiologically important molecules. Syntheses and structure elucidation combined with investigation of properties and applications of bile acids and their derivatives are of academic interest. The concept of using bile acids and their conjugates in nanoscience is a novel idea, which opens up fascinating prospects. In this article, an easy and simple route for obtaining N-lithocholyl-L-(cysteine ethyl ester) (3), capable of effectively capping and stabilizing metal nanoparticles, is described. The whole synthetic route needs only two steps giving a moderate to good yield. The gold NPs are characterized by elemental analysis, UV spectroscopy, and TEM. Addi…

Association Between Fibrosis Stage and Outcomes of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta -Analysis

2020

Background & Aims:\ud Biopsy-confirmed liver fibrosis is a prognostic factor for patients with nonalcoholic fatty liver disease (NAFLD). We performed a systematic review to quantify the prognostic value of fibrosis stage in patients with NAFLD and the subgroup of patients with nonalcoholic steatohepatitis (NASH) and to assess the evidence that change in fibrosis stage is a surrogate endpoint.\ud \ud Methods:\ud We searched the MEDLINE, Embase, Cochrane Library, and trial registry databases through August 2018 for prospective or retrospective cohort studies of liver-related clinical events and outcomes in adults with NAFLD or NASH. We collected data on mortality (all cause and liver rela…