Search results for "Gels"
showing 10 items of 671 documents
The Effect of the Side Chain on Gelation Properties of Bile Acid Alkyl Amides
2021
Abstract Six bile acid alkyl amide derivatives were studied with respect to their gelation properties. The derivatives were composed of three different bile acids with hexyl or cyclohexyl side chains. The gelation behaviour of all six compounds were studied for 36 solvents with varying polarities. Gelation was observed mainly in aromatic solvents, which is characteristic for bile‐acid‐based low molecular weight gelators. Out of 108 bile acid‐solvent combinations, a total of 44 gel systems were formed, 28 of which from lithocholic acid derivatives, only two from deoxycholic acid derivatives, and 14 from cholic acid derivatives. The majority of the gel systems were formed from bile acids with…
Probing the self-assembly and anti-glioblastoma efficacy of a cinnamoyl-capped dipeptide hydrogelator
2022
Herein, we introduce the first diphenylalanine dipeptide hydrogelator capped with the cinnamoyl functional group (Cin-L-F-L-F). We evaluate the effects of the cinnamoyl moiety on molecular self-assembly events and resultant physical properties of the hydrogel formed. In addition, we report our preliminary results of this dipeptide's cytotoxicity against glioblastoma (GBM) cancer cells. peerReviewed
Oligonucleotides-decorated-poly(N-vinyl pyrrolidone) nanogels for gene delivery
2013
Pulsed electron-beam irradiation of a semi-dilute poly(N-vinyl pyrrolidone) (PVP) aqueous solution in the presence of acrylic acid has led to a carboxyl functionalized nanogel system. Nanoparticles hydrodynamic size and surface charge density, in water and as a function of pH, were investigated by dynamic light scattering and laser doppler velocimetry, respectively. Nanogels (NGs) were proved not to be cytotoxic at the cellular level. Indeed, they rapidly bypass the cellular membrane to accumulate in specific cell portions of the cytoplasm, in the perinuclear area. The availability of pendant carboxyl groups on the crosslinked PVP NGs core prompted us to attempt their decoration with a sing…
Supramolecular Hydro- and Ionogels: A Study of Their Properties and Antibacterial Activity.
2017
Diimidazolium-based organic salts, bearing peptides or amino acids as anions have been synthesised and tested for their gelling ability in biocompatible solvents. These low molecular weight salts were successfully used as gelators in phosphate buffered saline (PBS) solution and ionic liquids. Then, the properties of the obtained soft materials were analysed in terms of melting temperature and gel strength as accounted for by rheological investigations. The gel-phase formation was studied by using UV/Vis and resonance light scattering measurements, whereas the morphology of the soft materials was analysed by using polarised optical microscopy and scanning electron microscopy. To get informat…
Entrepreneurs (novices vs. experts) and investors: Interaction and rationality dynamics (effectual vs. causal)
2019
The paper studies the mechanisms that govern the interactions between the entrepreneur (novice or expert) and the specific investors of emerging firms (business angels (BAs) and venture-capital firms (VCs)). Combining both literatures on entrepreneurship and entrepreneurial finance, our aim is to understand if the rationalities of these three actors help them or not to interact, and, to study how they influence each other during the firm's growth. In order to do so, we undertake two processual case studies. Our results show that effectual rationality underlines the interaction between the entrepreneur and the BAs at the creation of the firm, whilst causal rationality is helpful in the searc…
"Ungdomar blir too tired när de är too much i nätet" : engelskans påverkan på finska gymnasieelevers uppsatser i B-svenska
2014
Tämän tutkimuksen tarkoituksena oli selvittää, millä tavalla ja kuinka paljon englannin kielen vaikutus näkyy ruotsinkielisissä teksteissä, jotka oppilaat kirjoittivat lukio-opintojensa aikana. Tutkimuksen tavoitteena oli myös tutkia sitä, vähentyykö englannin kielen vaikutus sillä aikavälillä, jonka aikana tekstit on kirjoitettu. Tutkimukseen osallistui neljä oppilasta, joista kolme oli naispuolisia oppilaita ja yksi oli miespuolinen. Oppilaat kirjoittivat kolme tekstiä viidestä eri teemasta. Ensimmäinen teksti kaikista teemoista kirjoitettiin syksyllä 2010, toinen syksyllä 2011 ja kolmas keväällä 2012. Oppilaat osallistuivat Jyväskylän yliopiston Topling-tutkimushankkeeseen, jonka tavoitt…
Muntlig och skriftlig feedback på gymnasienivå : en fallstudie
2016
Opettajan antamalla palautteella on keskeinen rooli opetuksessa, sillä sen avulla oppilas saa tietää, miten hän etenee omassa oppimisprosessissansa. Lisäksi palautteella on vaikutus oppilaan motivaatioon ja itsetuntoon. Tämän tutkimuksen tavoitteena oli selvittää, miten lukiolaiset haluavat saada suullista ja kirjallista palautetta ruotsin ja englannin opetuksessa. Tarkastelin myös, miten opettajat antavat palautetta oppilaillensa ja onko kielten välissä havaittavissa mitään eroja. Tutkimusaineistoni muodostui 45 lukiolaisesta ja kahdesta opettajasta. Observoin kolme tuntia ruotsin opetusta ja kolme tuntia englannin opetusta, minkä jälkeen sekä lukiolaiset että opettajat vastasivat kyselyyn…