Search results for "Gene-Environment Interaction"

showing 5 items of 65 documents

Heritability of anterior chamber depth and axial length: a population-based twin study among 66 to 79-year old female twins.

2014

ocular refractionAnterior ChamberInheritance PatternsPopulation basedBiologyheritabilityRefraction Ocular03 medical and health sciences0302 clinical medicineTwins DizygoticInheritance PatternsHumansGene–environment interaction030304 developmental biologyAgedGenetics0303 health sciencesGeneral MedicineAxial lengthta3142Twins MonozygoticHeritabilityTwin studyta3125OphthalmologyAxial Length Eye030221 ophthalmology & optometryFemaleGene-Environment InteractionDemographyActa ophthalmologica
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Association between communication deviance of adoptive parents and formal thought disorder of adoptee when the length of parents' speech is standardi…

2012

Communication Deviance (CD) is considered to be a potential environmental factor in gene-environment interaction leading to offspring psychopathology, for example thought disorders and mental disturbances. The aim of this study was to examine the relationship between formal thought disorder of genetic high-risk and low-risk adoptees and Communication Deviance of adoptive parents when the length of their speech is standardized with spoken words (Word Count, WC). The sample included a group of 58 adoptees at high genetic risk for schizophrenia spectrum disorders and a comparison group of 96 low-risk adoptees and their adoptive families. Communication Deviance (CD) of the adoptive parents was …

schizophreniaottovanhemmatskitsofreniacommunication devianceadoptiothought disordersAdoption studygene-environment interaction
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Large-scale genotyping identifies 41 new loci associated with breast cancer risk

2013

Journal article Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ~9% of the familial risk of the disease. We report here a meta-analysis of 9 genome-wide association studies, including 10,052 breast cancer cases and 12,575 controls of European ancestry, from which we selected 29,807 SNPs for further genotyping. These SNPs were genotyped in 45,290 cases and 41,880 controls of European ancestry from 41 studies in the Breast Cancer Association Consortium (BCAC). The SNPs were genotyped as part of a collaborative genotyping experiment involving four consortia (Collaborat…

signaling pathwayGenotypingGenotypeSingle-nucleotide polymorphismGenome-wide association studyBreast NeoplasmsconsortiumBiologyBreast Neoplasms; Case-Control Studies; Cooperative Behavior; Female; Gene-Environment Interaction; Genetic Loci; Genome-Wide Association Study; Genotype; Humans; Meta-Analysis as Topic; Polymorphism Single Nucleotide; Risk Factors; Genetic Predisposition to Disease; GeneticsPolymorphism Single NucleotideArticle03 medical and health sciences0302 clinical medicineBreast cancerSDG 3 - Good Health and Well-beingMeta-Analysis as TopicRisk FactorsGenotypecommon variantsexpressionGeneticsmedicineHumansGenetic Predisposition to DiseasePolymorphismCooperative BehaviorgeneGenotypinghormone-related protein030304 developmental biologyGenetic associationGenetics0303 health sciencesBreast cancer susceptibilityCancerSingle Nucleotidemedicine.diseaseconfer susceptibilitysusceptibility loci3. Good health14q24.1 rad51l1TOX3Genetic Loci030220 oncology & carcinogenesisCase-Control Studiesgenome-wide associationFemaleGene-Environment InteractionGenome-Wide Association Study
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The challenges of GxE research: A rejoinder

2017

ta511genetiikka030505 public healthHealth (social science)ympäristötekijätta1184genetic risk scoresbiomarkersta3142riskitekijätgene-environment interactionsHealth outcomes01 natural sciencesData science010104 statistics & probability03 medical and health sciencesHistory and Philosophy of Sciencemarkkeritidentificationhealth outcomesIdentification (biology)terveyserot0101 mathematics0305 other medical sciencePsychologySocial Science & Medicine
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Factors behind Leisure-Time Physical Activity Behavior Based on Finnish Twin Studies: The Role of Genetic and Environmental Influences and the Role o…

2014

Different approaches are being taken to clarify the role of various factors in the development of physical activity behaviors. Genetic studies are a new area of physical activity research and also the motives for physical activity have been widely studied. The purpose of this paper is to review the findings emerging from the longitudinal genetic studies on leisure-time physical activity and to evaluate the associations between motivational factors and leisure-time physical activity. The focus is to review recent findings of longitudinal Finnish twin studies. The results of the latest longitudinal Finnish twin studies point to the existence of age-specific genetic and environmental influence…

ympäristötekijätLeisure timePhysical fitnessPhysical activityphysical activitylcsh:MedicineReview ArticleMotor ActivityGeneral Biochemistry Genetics and Molecular BiologyDevelopmental psychologyLeisure Activitiesenvironmental influenceIntrinsic motivationHumansYoung adultGene–environment interactionFinlandkaksostutkimusBehaviorMotivationGeneral Immunology and Microbiologyperinnöllisyystiedebusiness.industrylcsh:RGeneral Medicineleisure-timeTwin studykaksosettwin studiesgenetic influenceperimäGene-Environment InteractionbusinessPsychologyPhysical activity behaviorfyysinen aktiivisuusvapaa-aikaBioMed Research International
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