Search results for "Generation"
showing 10 items of 3050 documents
La rigenerazione urbana di Aalborg : un modello di sviluppo sostenibile per il futuro delle città
2022
Uno dei maggiori eventi che ha portato la città di Aalborg, capoluogo dello Jutland settentrionale, alla ribalta internazionale è stato lo svolgimento della prima conferenza europea sulle città sostenibili (European Conference on Sustainable Cities and Towns). Nel 1994 il Consiglio internazionale per le iniziative ambientali locali (ICLEI – Local Governments for Sustainability) ha scelto Aalborg per riflettere in che modo le città, principali responsabili del cambiamento climatico, del consumo delle risorse del pianeta e dell’inquinamento ambientale, potessero cambiare i loro trend di sviluppo per indirizzarli verso una dimensione più sostenibile. Alla conferenza, che si è svolta sotto il p…
The Art of Being Ethical and Responsible : Print Media Debate on Final Disposal of Spent Nuclear Fuel in Finland and Sweden
2022
AbstractAfter decades of preparation, the final disposal of spent nuclear fuel has reached the construction stage in Finland, and the neighboring Sweden is likely to soon follow in the footsteps. These Nordic countries rely on a similar technical concept based on passive safety, advocated as a means of minimizing the burden to future generations. The scholarly literature on the ethics of nuclear waste management has thus far paid little attention to the views of the broader publics on the associated ethical challenges. This article helps to fill the gap through a longitudinal and comparative analysis of ethical discussion of the final disposal of SNF in news articles and letters to the edit…
Sorbitol-penetration enhancer containing vesicles loaded with baicalin for the protection and regeneration of skin injured by oxidative stress and UV…
2018
Abstract Aiming at improving the protective effects of baicalin on the skin, new highly-biocompatible penetration enhancer containing vesicles (PEVs) were developed by modifying the base formulation of transfersomes with sorbitol, thus obtaining sorbitol-PEVs. An extensive evaluation of the physico-chemical features of both transfersomes and sorbitol-PEVs was carried out. Transfersomes were mainly close-packed, multi-compartment vesicles, while sorbitol-PEVs appeared mostly as single, spherical, unilamellar vesicles. All the vesicles were small in size (∼128 nm) and negatively charged (∼−67 mV), without significant differences between the formulations. The in vitro delivery of baicalin to i…
Another defence of enumerated types
1991
I claim that enumerations, while of course not strictly necessary, are an elegant and useful facility in modern programming languages. I try to show that arguments recently given against them are weak at best and bogus a t worst, for general-purpose programming. Some related issues on types in programming languages are touched as well. These make it even more questionable whether Oberon marks progress or regress in language design.
A Rule-Based System for Hardware Configuration and Programming of IoT Devices
2019
Simplifying programming, deployment, and configuration of heterogeneous networked IoT devices requires networking, hardware, representation of knowledge and concepts, design and programming skills. In fact, IoT applications are mostly built by adopting different existing paradigms and technologies on a case-by-case basis. As a result, programming tools hinder adaptability and interoperability of applications with their rigidity. In this paper, we propose a rule-based system that configures and programs IoT devices automatically. The rule base holds formal specifications about hardware platforms, networking protocols, physical world concepts, and applications. Provided with a high-level appl…
Programming languages and dynamic instructional tools: Addressing students’ knowledge base
1992
The chapter presents an instructional computer environment to be used in introductory Pascal programming classes. Traditional programming courses do not foster the kind of knowledge structures that are the trademark of expert programmers. These knowledge structures or programming templates provide programmers with a ready-to-use library of routines from which they draw when writing a new program. Developed as a hypertext tool, TAP (Template Assisted Programming) is an instructional environment to teach programming that emphasizes the development and use of such a library of routines by presenting students with a multiple representation of programming knowledge. In TAP students can (a) switc…
Vulnerability of peripheral catecholaminergic neurons to MPTP is not regulated by alpha-synuclein.
2010
Although generally considered a prototypical movement disorder, Parkinson's disease is commonly associated with a broad-spectrum of non-motor symptoms, including autonomic dysfunctions caused by significant alterations in catecholaminergic neurons of the peripheral sympathetic nervous system. Here we present evidence that alpha-synuclein is highly expressed by sympathetic ganglion neurons throughout embryonic and postnatal life and that it is found in tyrosine hydroxylase-positive sympathetic fibers innervating the heart of adult mice. However, mice deficient in alpha-synuclein do not exhibit any apparent alterations in sympathetic development. Sympathetic neurons isolated from mouse embryo…
Enhancing Collaborative Governance to Build Active Citizenship through Social Inclusion in Historical Neighborhood Regeneration: A Dynamic Performanc…
2021
Active citizenship and collaborative governance can be supported to enhance urban regeneration and social inclusion through Dynamic Performance Governance (DPG). The problem of urban decay and urban decline is identified as the main problem that continues to affect cities and urban areas. The study focuses on the urban regeneration experience of the historic urban neighborhood of Ballaro which is located in the historic city of Palermo. Urban regeneration is essential for transforming urban neighborhoods which are at risk of decline and blight. However, the lack of a social aspect such as social inclusion through active citizenship was identified to affect the sustainability of urban regene…
Errors in Monte Carlo simulations using shift register random number generators
1996
We report large systematic errors in Monte Carlo simulations of the tricritical Blume-Capel model using single spin Metropolis updating. The error, manifest as a $20\%$ asymmetry in the magnetisation distribution, is traced to the interplay between strong triplet correlations in the shift register random number generator and the large tricritical clusters. The effect of these correlations is visible only when the system volume is a multiple of the random number generator lag parameter. No such effects are observed in related models.
The Erythrocytic Hypothesis of Brain Energy Crisis in Sporadic Alzheimer Disease: Possible Consequences and Supporting Evidence
2020
Alzheimer’s disease (AD) is a fatal form of dementia of unknown etiology. Although amyloid plaque accumulation in the brain has been the subject of intensive research in disease pathogenesis and anti-amyloid drug development; the continued failures of the clinical trials suggest that amyloids are not a key cause of AD and new approaches to AD investigation and treatment are needed. We propose a new hypothesis of AD development based on metabolic abnormalities in circulating red blood cells (RBCs) that slow down oxygen release from RBCs into brain tissue which in turn leads to hypoxia-induced brain energy crisis; loss of neurons; and progressive atrophy preceding cognitive dysfunction. This …