Search results for "Generation"
showing 10 items of 3050 documents
Contributions to Branch-and-Price-and-Cut Algorithms for Routing Problems
2019
This article deals with new exact branch-and-price-and-cut algorithms for the solution of routing problems. Specialized methods for the pickup-and-delivery problem (PDP), the truck-and-trailer routing problem (TTRP), the periodic vehicle routing problem (PVRP) and a service network design and hub location problem (SNDHLP) are presented. We develop a new technique for the acceleration of bidirectional labeling algorithms by a dynamic choice of the merge point. Moreover, for variants of the PDP, the bidirectional labeling can be effectively applied for the first time. In the TTRP, we model the extension to a 2 days planning horizon and the consideration of a quantity-dependent transfer time. …
Branch-price-and-cut algorithms for the pickup and delivery problem with time windows and multiple stacks
2016
Abstract This paper proposes models and algorithms for the pickup and delivery vehicle routing problem with time windows and multiple stacks. Each stack is rear-loaded and is operated in a last-in-first-out (LIFO) fashion, meaning that when an item is picked up, it is positioned at the rear of a stack. An item can only be delivered if it is in that position. This problem arises in the transportation of heavy or dangerous material where unnecessary handling should be avoided, such as in the transportation of cars between car dealers and the transportation of livestock from farms to slaughterhouses. To solve this problem, we propose two different branch-price-and-cut algorithms. The first sol…
Stabilized branch-price-and-cut for the commodity-constrained split delivery vehicle routing problem
2019
Abstract In the commodity-constrained split delivery vehicle routing problem (C-SDVRP), customer demands are composed of sets of different commodities. The C-SDVRP asks for a minimum-distance set of routes such that all customer demands are met and vehicle capacities are respected. Moreover, whenever a commodity is delivered by a vehicle to a customer, the entire amount requested by this customer must be provided. Different commodities demanded by one customer, however, can be delivered by different vehicles. Thus, the C-SDVRP is a relaxation of the capacitated vehicle routing problem and a restriction of the split delivery vehicle routing problem. For its exact solution, we propose a branc…
Signaling Reduction in 5G eV2X Communications Based on Vehicle Grouping
2019
Groups of users, sometimes referred to as clusters, have been exploited in several works to enhance wireless communications. Leveraging on previous ideas, the main goal of this paper is to take advantage of vehicle grouping in order to reduce uplink signaling in fifth generation (5G) vehicular communications. Several schemes to reduce uplink signaling are proposed and particularized in two specific 5G uses cases: the reporting of Channel Busy Ratio (CBR), and the reporting of beam measurements in beam management procedures. The achieved signaling reduction is analytically evaluated in an example of urban scenario with high vehicle densities for different group sizes. The signaling load can …
Performance Study of Twisted Darrieus Hydrokinetic Turbine With Novel Blade Design
2021
Abstract Twisted Darrieus water turbine is receiving growing attention for small-scale hydropower generation. Accordingly, the need for raised water energy conversion incentivizes researchers to focus on the blade shape optimization of twisted Darrieus turbine. In view of this, experimental analysis has been performed to appraise the efficiency of a spiral Darrieus water rotor in the present work. To better the performance parameters of the studied water rotor with twisted blades, three novel blade shapes, namely U-shaped blade, V-shaped blade, and W-shaped blade, have been numerically tested using a computational fluid dynamics three-dimensional numerical model. The maximum power coefficie…
Vitamin D and Parkinson's Disease.
2022
Vitamin D is a fat-soluble secosteroid, traditionally considered a key regulator of bone metabolism, calcium and phosphorous homeostasis. Its action is made possible through the binding to the vitamin D receptor (VDR), after which it directly and indirectly modulates the expression of thousands of genes. Vitamin D is important for brain development, mature brain activity and associated with many neurological diseases, including Parkinson’s disease (PD). High frequency of vitamin D deficiency in patients with Parkinson’s disease compared to control population was noted nearly twenty years ago. This finding is of interest given vitamin D’s neuroprotective effect, exerted by the action of neur…
Separated children & forbidden roots : removals of part-indigenous children as part of Australia's assimilation policy in the 1950s-1960s
2013
1950-ja 1960-luvuilla Australiassa oli kaksi merkittävää poliittista käytäntöä, joilla oli merkittävä vaikutus maan alkuperäisväestöön nimittäin assimilaatio sekä osittain valkoista alkuperää olevien aboriginaalilasten pakkohuostaanotot. Tutkielma käsittelee Australian assimilaatio politiikkaa, sen keinoja ja taustoja sekä varsinkin sen yhteyttä aboriginaalilasten pakkohuostaanottoihin. Jo 1800-luvulta lähtien Australiassa oli ollut vallalla käytäntö erottaa aboriginaalilapsia vanhemmistaan ja yhteisöistään koulutukset, parempien elinolojen tai kristillisen lähetystyön velvoittamana. Heistä koulutettiin halpaa, kristillistä työvoimaa valloitetuille alueille. 1920-luvulta alkanut osittain va…
Problématiques de la nutrition en ophtalmologie – application à la dégénérescence maculaire liée à l’âge
2014
Nutrition in ophthalmology – clinical application to age-related macular degeneration «Let food be your medicine.» This contribution from Hippocrates is still timely addressed, especially in the field of ophthalmology. Observational epidemiology reports close associations between food habits and the risk or prevention of several ocular pathologies such as cataract or Age-related Macular Degeneration (AMD). Anti-oxidant vitamins, minerals and lipids are the nutrients that have been the most widely studied. Interventional epidemiology and experimental works partially corroborated these findings. Unexpectedly, the benefit of long chain omega 3 polyunsaturated fatty acids in the prevention of l…
Widening use of dexamethasone implant for the treatment of macular edema
2017
Vincenza Bonfiglio, Michele Reibaldi, Matteo Fallico, Andrea Russo, Alessandra Pizzo, Stefano Fichera, Carlo Rapisarda, Iacopo Macchi, Teresio Avitabile, Antonio Longo Department of Ophthalmology, University of Catania, Catania, Italy Abstract: Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis. The implant is formulated in a biodegradable copolymer to release the active ingredient within the vitreous chamber for up to 6 months after an intravitreal injection, allowing a prolonged interval of effica…
Surface charges at the CaF2/water interface allow very fast intermolecular vibrational-energy transfer
2020
Abstract We investigate the dynamics of water in contact with solid calcium fluoride, where at low pH, localized charges can develop upon fluorite dissolution. We use 2D surface‐specific vibrational spectroscopy to quantify the heterogeneity of the interfacial water (D2O) molecules and provide information about the sub‐picosecond vibrational‐energy‐relaxation dynamics at the buried solid/liquid interface. We find that strongly H‐bonded OD groups, with a vibrational frequency below 2500 cm−1, display very rapid spectral diffusion and vibrational relaxation; for weakly H‐bonded OD groups, above 2500 cm−1, the dynamics slows down substantially. Atomistic simulations based on electronic‐structu…