Search results for "Generation"
showing 10 items of 3050 documents
Early structural degeneration of Mitroflow aortic valve: Another issue in addition to the mismatch?
2018
We reported two cases of early structural valve degeneration (SVD) with Mitroflow prosthesis in aortic position in patients above the age of 65 years. Microscopic aspects have been analysed to investigate the intrinsic mechanism of SVD. New techniques to improve the structure and the preservation of this prosthesis are needed in order to reduce potential dangerous early complications.
Identification Of P.Leu167Del Apoe Gene Mutation By Next Generation Sequencing In A Large Hypercholesterolemic Family
2019
Neuronal cell cycle: the neuron itself and its circumstances.
2015
Neurons are usually regarded as postmitotic cells that undergo apoptosis in response to cell cycle reactivation. Nevertheless, recent evidence indicates the existence of a defined developmental program that induces DNA replication in specific populations of neurons, which remain in a tetraploid state for the rest of their adult life. Similarly, de novo neuronal tetraploidization has also been described in the adult brain as an early hallmark of neurodegeneration. The aim of this review is to integrate these recent developments in the context of cell cycle regulation and apoptotic cell death in neurons. We conclude that a variety of mechanisms exists in neuronal cells for G1/S and G2/M check…
Lack of Dystrophin Affects Bronchial Epithelium in mdx Mice
2016
Mild exercise training may positively affect the course of Duchenne Muscular Dystrophy (DMD). Training causes mild bronchial epithelial injury in both humans and mice, but no study assessed the effects of exercise in mdx mice, a well known model of DMD. The airway epithelium was examined in mdx (C57BL/10ScSn-Dmdmdx) mice, and in wild type (WT, C57BL/10ScSc) mice either under sedentary conditions (mdx-SD, WT-SD) or during mild exercise training (mdx-EX, WT-EX). At baseline, and after 30 and 45 days of training (5 d/wk for 6 weeks), epithelial morphology and markers of regeneration, apoptosis, and cellular stress were assessed. The number of goblet cells in bronchial epithelium was much lower…
A Hardware and Secure Pseudorandom Generator for Constrained Devices
2018
Hardware security for an Internet of Things or cyber physical system drives the need for ubiquitous cryptography to different sensing infrastructures in these fields. In particular, generating strong cryptographic keys on such resource-constrained device depends on a lightweight and cryptographically secure random number generator. In this research work, we have introduced a new hardware chaos-based pseudorandom number generator, which is mainly based on the deletion of an Hamilton cycle within the $N$ -cube (or on the vectorial negation), plus one single permutation. We have rigorously proven the chaotic behavior and cryptographically secure property of the whole proposal: the mid-term eff…
Aging Societies and Intergenerational Solidarity
2010
Due to an increased life expectancy—more people over 65 years old and never before seen numbers of older adults above 85—all countries around the world are nowadays facing rapid demographic changes...
Energy management of multi-carrier smart buildings for integrating local renewable energy systems
2016
The proposed paper aims at defining a Building Management System (BMS) able to control energy flows inside a smart building integrated with various energy networks and Renewable Energy Resources (RES). The smart building envisaged in this work interacts with different energy carriers and is equipped with cogeneration and RES systems, as well as storage devices, which enable a certain degree of flexibility in the energy usage. The smart building is modelled as a multi-carrier hub, by defining the graphical and mathematical model of the building system. Moreover, the control criteria of the BMS are explained and the implementation of the BMS itself is depicted, along with some early results. …
The Waterfront Theorem: an integrated and creative planning approach
2016
Waterfronts are sensitive interfaces between land and sea, creative interfaces between urban and environmental components, social interfaces between nodes and networks. They not only coincide with the areas of infrastructure that are gathering on the coast, not only with the shoreline or the environmental components of the coastal territories. They are hired by the project as complex interaction of crossing flows, stratified identity of urban communities: fundamental element of the environmental system, synthesis of landscape, space and community, a place of solidification of the identity of the social, cultural and economic community (Carta, 2009). The management of urban interface of wate…
Augmented Cities in the Neoanthropocene
2021
Contemporary cities could be considered vibrant organisms of places and communities, of data and information, of sensors and actuators, and of actions and reactions generated by people and environment both. Cities must be more responsive to our behavioral changes, enabling devices for enhancing our contemporary life. We would be able to build a more efficient urban environment, able to sense, to understand and to act every day and for everyone. In the post-city age and beyond the smart city, Augmented City is a new paradigm that perceives the demands of more networked, knowledge-based, and creative society that answers to the global change by a new circular metabolism. The Augmented City is…
Digital Mosaic Frameworks - an overview
2007
Art often provides valuable hints for technological innovations especially in the field of Image Processing and Computer Graphics. In this paper we survey in a unified framework several methods to transform raster input images into good quality mosaics. For each of the major different approaches in literature the paper reports a short description and a discussion of the most relevant issues. To complete the survey comparisons among the different techniques both in terms of visual quality and computational complexity are provided.