Search results for "Genou"

showing 10 items of 610 documents

Desalination effluents and the establishment of the non-indigenous skeleton shrimp Paracaprella pusilla Mayer, 1890 in the south -eastern Mediterrane…

2019

A decade long monitoring programme has revealed a flourishing population of the non-indigenous skeleton shrimp Paracaprella pusilla in the vicinity of outfalls of desalination plants off the Mediterranean coast of Israel. The first specimens were collected in 2010, thus predating all previously published records of this species in the Mediterranean Sea. A decade-long disturbance regime related to the construction and operation of the plants may have had a critical role in driving the population growth. University of Palermo FFR 2018

Amphipoda Crustacea Caprellidae brine-effluent plume chronic disturbance regime environmental monitoringMediterranean climatebrine-effluent plumeEcologyCaprellidaeSettore BIO/05 - ZoologiaIntroduced speciesDesalinationInvasive speciesIndigenousShrimpFisheryGeographyAmphipodachronic disturbance regimeEffluentEcology Evolution Behavior and SystematicsSouth easternenvironmental monitoring
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Toxicity assessment and biodegradation potential of water-soluble sludge containing 2,4,6-trinitrotoluen

2013

The water-soluble phase of trinitrotoluene-containing sludge (SLP) was characterized with regard to trinitrotoluene (TNT) concentration, ecotoxicity, and a model biodegradation experiment as evaluation criteria for further development of appropriate treatment technologies. SLP contained 67.8 mg TNT/l. The results of germination and root-elongation tests indicated that SLP had a species-specific phytotoxic effect. The results of a 21 day degradation experiment demonstrated TNT conversion to 4-amino-2,6-DNT and 2-amino-4,6-DNT, with a simultaneous reduction in the total concentration of nitroaromatics. Addition of inoculum stimulated the TNT degradation process. The presence of the sludge sol…

Aniline CompoundsEnvironmental EngineeringSewagebiodegradation; enzyme activity; indigenous microorganisms; phytotoxicity; solubility; TNTChemistryGerminationBiodegradationEcotoxicologymusculoskeletal systemPlant RootsBiodegradation EnvironmentalMicrobial population biologyGerminationEnvironmental chemistryVattenbehandlingToxicity TestsToxicityWater TreatmentTrinitrotolueneDegradation (geology)Water treatmentEcotoxicityTrinitrotolueneWater Science and Technology
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Risk estimation for air travel-induced malaria transmission in central Europe – A mathematical modelling study

2019

Abstract Background Aim of our study was to identify conditions under which malaria transmission caused by imported infectious mosquitoes or travellers could occur at large central European airports, and if such transmission could be sustained by indigenous mosquitoes. Methods We developed a deterministic and a stochastic compartmental Susceptible-Exposed-Infectious-Recovered-Susceptible (humans)/Susceptible-Exposed-Infectious (mosquitoes) model with two mosquito (imported Anopheles gambiae, indigenous A. plumbeus) and three human (travellers, airport personnel exposed/not exposed to imported A. gambiae) populations. We assessed various scenarios to identify combinations of model parameters…

Anopheles gambiae030231 tropical medicineMosquito VectorsIndigenouslaw.invention03 medical and health sciences0302 clinical medicinelawEnvironmental healthAnophelesparasitic diseasesmedicineAnimalsHumans030212 general & internal medicineEstimationbiologyPublic Health Environmental and Occupational HealthOutbreakmedicine.diseasebiology.organism_classificationMalariaEuropeAir TravelInfectious DiseasesTransmission (mechanics)GeographyInduced malariahuman activitiesDisease transmissionMalariaTravel Medicine and Infectious Disease
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Identification of Biphenyl-Based Hybrid Molecules Able To Decrease the Intracellular Level of Bcl-2 Protein in Bcl-2 Overexpressing Leukemia Cells

2009

With the aim of enhancing the structural complexity and diversity of an existing collection of bi- and terphenyl compounds, we synthesized hybrid molecules comprising of spirocyclic ketones (a complexity-bearing core) and bi/terphenyls (privileged fragments). Compounds 1, 3, 4, and 6 showed well-defined activity on apoptosis and differentiation, making them potential leads for development as new anticancer agents and chemical probes to study signaling networks in neoplastic cells.

Antineoplastic AgentsApoptosisHL-60 CellsChemical synthesisStructure-Activity RelationshipLeukemia Myelogenous Chronic BCR-ABL PositiveTerphenyl CompoundsDrug DiscoverymedicineHumansSpiro CompoundsChemistryBiphenyl CompoundsCell DifferentiationBiological activityKetonesmedicine.diseaseIn vitroLeukemiaProto-Oncogene Proteins c-bcl-2BiochemistryApoptosisCell cultureMolecular MedicineTerphenyl CompoundsK562 CellsIntracellularJournal of Medicinal Chemistry
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Antimicrobial and antiproliferative activity of Peucedanum nebrodense (Guss.) Strohl.

2003

Abstract Acetone extract of Peucedanum nebrodense (Guss.) Strohl., a rare endemic species from the Madonie mountains (Sicily), was tested in vitro for its antimicrobial activity against bacterial reference strains and antiproliferative activity against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and L1210 (murine leukemia) cell lines. The acetone extract showed antiproliferative IC 50 values in the range of 14–0.27 μg/ml.

Antineoplastic AgentsHL-60 CellsBiologyPlant RootsAcetoneMiceAnti-Infective Agentshemic and lymphatic diseasesDrug DiscoverymedicinePeucedanum nebrodenseCoumarins Antimicrobial Antiproliferative activityAnimalsHumansLeukemia L1210PharmacologyTraditional medicinePlant ExtractsBiological activityPlant Components AerialAntimicrobialmedicine.diseaseIn vitroLeukemiaCell cultureK562 CellsPeucedanum nebrodenseCell DivisionChronic myelogenous leukemiaK562 cellsApiaceaeJournal of ethnopharmacology
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Polycyclic aromatic hydrocarbons and trace metal contamination of coastal sediment and biota from Togo

2011

The state of contamination of tropical environments, particularly in Africa, remains a relatively under explored subject. Here, we determined polycyclic aromatic hydrocarbon (PAH) and trace metal concentrations in coastal sediment and biota samples (fish and mussels) from Togo (West Africa). In the sediments, the ∑21 PAH concentrations ranged from4 ng g(-1) to 257 ng g(-1), averaging 92 ng g(-1). Concentration ratios of low molecular weight PAHs (2-3 rings) versus high molecular weight PAHs (≥4 rings) were always lower than 1 (ranging from 0.08 to 0.46) indicating that high molecular weight PAHs were dominant in all sediment samples, and that PAHs originated mainly from anthropogenic combus…

Aquatic OrganismsGeologic SedimentsPolycyclic aromatic hydrocarbonManagement Monitoring Policy and LawAnimalsSeawaterTrace metalPolycyclic Aromatic Hydrocarbonschemistry.chemical_classificationChemistryTerrigenous sedimentFishesPublic Health Environmental and Occupational HealthSedimentBiotaGeneral MedicineBiotaBivalviaPhosphoriteMetalsTogoEnvironmental chemistryBioaccumulationEnrichment factorWater Pollutants ChemicalEnvironmental MonitoringJournal of Environmental Monitoring
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Agronomic Management of Indigenous Mycorrhizas

2008

Many of the advantages conferred to plants by arbuscular mycorrhiza (AM) are associated to the ability of AM plants to explore a greater volume of soil through the extraradical mycelium. Sieverding (1991) estimates that for each centimetre of colonized root there is an increase of 15 cm3 on the volume of soil explored, this value can increase to 200 cm3 depending on the circumstances. Due to the enhancement of the volume of soil explored and the ability of the extraradical mycelium to absorb and translocate nutrients to the plant, one of the most obvious and important advantages resulting from mycorrhization is the uptake of nutrients. Among of which the ones that have immobilized forms in …

Arbuscular mycorrhizaAgronomic managementbiologyAgronomyAgroforestryArbuscilar MycorrhizaPlant soilbiology.organism_classificationCover cropIndigenous
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The indigenous settlement of Monte Iato (western Sicily): an ethnoarchaeometric approach for outlining local Archaic ceramic productions

2021

AbstractAn ethnoarchaeometric approach has been followed to identify the textural and compositional characteristics of the ceramic pastes produced in ancient Iaitas/Ietas, an indigenous site located in western Sicily on Monte Iato, a few tens of kilometres from Palermo. This approach was primarily motivated by the lack of discovered Archaic kilns or production sites/workshops and the inability to identify reference groups. Raw clays were sampled in the territory of San Cipirello and San Giuseppe Iato (today’s municipalities both sited on the northern slopes of Monte Iato), together with representative historic tiles and bricks locally produced until fairly recently. Grain-size analysis and …

Archeology10108 Institute of ArchaeologySettlement (structural)KilnChaîne opératoireExcavationArchaeologyIndigenousGeographyChemical markerArchaeologyvisual_artAnthropologyvisual_art.visual_art_medium3314 AnthropologyArchaic age (seventh–fifth century BCE) Ceramic production Clay sources Ethnoarchaeometry Monte Iato Sicily3302 ArcheologyPotteryCeramic1204 Archeology (arts and humanities)Settore GEO/09 -Georis. Miner.e Appl.Mineral.-Petrogr. per l'Ambi.ed i B.Cult.900 History
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Compositional reference for the documented Archaic production of indigenous matt-painted pottery at Entella (Western Sicily)

2015

This contribution is focused on a specific class of indigenous Archaic pottery (sixth and fifth century BC) with matt-painted geometric decoration that was recovered in large quantities in the excavations at Entella, an indigenous site located in western Sicily. The site of Entella was strategically considerable in this part of Sicily, controlling the north-south routes running along the river Belice. Kiln structures were attested at Entella that, until today, it is the only Archaic site in the area with an unmistakable evidence of production of fine pottery. The present research is aimed at yielding a complete petrographic and chemical characterization of the table ware produced at Entella…

ArcheologyHistoryPetrography020101 civil engineeringMatt-painted table ware02 engineering and technologyAncient history010502 geochemistry & geophysics01 natural sciencesArchaeometryIndigenous0201 civil engineeringArchaeological sciencePetrographyCeramic productionTable (landform)EntellaSicilySettore GEO/09 -Georis. Miner.e Appl.Mineral.-Petrogr. per l'Ambi.ed i B.Cult.0105 earth and related environmental sciencesArchaic ageExcavationArchaeologyChemistryAnthropologyPotteryArchaeological and Anthropological Sciences
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Anaplastic Thyroid Carcinoma: A ceRNA Analysis Pointed to a Crosstalk between SOX2, TP53, and microRNA Biogenesis.

2014

It has been suggested that cancer stem cells (CSC) may play a central role in oncogenesis, especially in undifferentiated tumours. Anaplastic thyroid carcinoma (ATC) has characteristics suggestive of a tumour enriched in CSC. Previous studies suggested that the stem cell factorSOX2has a preeminent hierarchical role in determining the characteristics of stem cells in SW1736 ATC cell line. In detail, silencing SOX2 in SW1736 is able to suppress the expression of the stem markers analysed, strongly sensitizing the line to treatment with chemotherapeutic agents. Therefore, in order to further investigate the role of SOX2 in ATC, a competing endogenous RNA (ceRNA) analysis was conducted in order…

Article SubjectEndocrinology Diabetes and MetabolismSOX2Stem cell factorAnaplastic Thyroid carcinomaBiologyBioinformaticsmedicine.disease_causelcsh:Diseases of the endocrine glands. Clinical endocrinologySettore MED/13 - EndocrinologiaEndocrinologySOX2Cancer stem cellmicroRNAmedicineGene silencinglcsh:RC648-665microRNAEndocrine and Autonomic SystemsCompeting endogenous RNAceRNACancer researchStem cellCarcinogenesisResearch ArticleInternational journal of endocrinology
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